APILIMOD MESYLATE
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- CAS号:
- 870087-36-8
- 英文名:
- ApiliMod (Mesylate)
- 英文别名:
- LAM-002A;Apilimodmesilate;STA5326 mesylate;AIT-101 mesylate;STA-5326 mesylate;STA 5326 mesylate;Apilimod dimesylate;ApiliMod (Mesylate);Apilimodmesylate, >98%;Dimethanesulfonic acid
- 中文名:
- APILIMOD MESYLATE
- 中文别名:
- 双甲磺酸;阿匹莫德甲磺酸盐;阿吡莫德甲磺酸盐;阿匹莫德二甲磺酸酯;阿吡莫德二甲磺酸盐;APILIMOD甲磺酸盐;阿吡莫德甲磺酸盐, >98%;抑制剂Apilimod mesylate;抑制剂Apilimod mesylate;阿吡莫德甲磺酸盐,10 MM DMSO 溶液
- CBNumber:
- CB72685921
- 分子式:
- C24H30N6O5S
- 分子量:
- 514.6
- MOL File:
- 870087-36-8.mol
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APILIMOD MESYLATE化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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形态:
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Powder
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颜色:
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White to off-white
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APILIMOD MESYLATE性质、用途与生产工艺
Apilimod mesylate (STA-5326 mesylate) 是一种有效的细胞因子 interleukin-12 (IL-12) 和 interleukin-23 (IL-23) 的口服抑制剂，具有治疗某些自身免疫和炎性疾病的潜力。Apilimod mesylate (STA-5326 mesylate) 可抑制IL-12，在IFN-γ/SAC刺激的人PBMC细胞、人单核细胞和小鼠PBMC细胞中，对应的IC50值分别为1 nM、1 nM和2 nM。Apilimod mesylate (STA-5326 mesylate) 也是一种具有细胞通透性的小分子化合物，抑制PIKfyve，IC50为14 nM。
| Target | Value |
IL-12
(in IFN-γ/SAC-stimulated human PBMCs)
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1 nM
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IL-12
(in human monocytes)
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1 nM
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IL-12
(in mouse PBMCs)
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2 nM
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PIKfyve
(Cell-free assay)
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14 nM
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APILIMOD MESYLATE
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/09/19 | S0785 | APILIMOD MESYLATE
Apilimod mesylate | 870087-36-8 | 5mg | 1204.61元 |
| 2025/09/19 | S0785 | Apilimod mesylate | 870087-36-8 | 10mM (1mL in DMSO) | 1367.73元 |
870087-36-8, APILIMOD MESYLATE 相关搜索:
- 抑制剂
- 药靶配体
- C25H34N6O8S2
- C23H26N6O22CH4O3S
- 双甲磺酸
- N-[(E)-(3-甲基苯基)亚甲基氨基]-6-吗啉-4-基-2-(2-吡啶-2-基乙氧基)嘧啶-4-胺
- 抑制剂Apilimod mesylate
- 抑制剂Apilimod mesylate
- Apilimod mesylate (阿匹莫德)
- 阿吡莫德甲磺酸盐,10 MM DMSO 溶液
- 阿匹莫德二甲磺酸酯
- 阿吡莫德二甲磺酸盐
- 4-(6-(2-(3-甲基亚苄基)肼基)-2-(2-(吡啶-2-基)乙氧基)嘧啶-4-基)吗啉二甲基磺酸盐
- APILIMOD甲磺酸盐
- 阿匹莫德甲磺酸盐
- 阿吡莫德甲磺酸盐, >98%
- 阿吡莫德甲磺酸盐
- 870087-36-8
- (e)-4-(6-(2-(3-methylbenzylidene)hydrazineyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate
- Dimethanesulfonic acid
- LAM-002A
- AIT-101 mesylate
- Apilimod mesylate, 10 mM in DMSO
- Benzaldehyde, 3-methyl-,[6-(4-morpholinyl)-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]hydrazone,dimethanesulfonate
- Apilimod (STA-5326) mesylate
- Apilimod,inhibit,Interleukin Related,STA-5326,Fab1,STA5326,STA 5326,Apilimod mesylate,Inhibitor,PIKfyve
- 4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate
- (E)-4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate
- Apilimodmesilate
- Apilimod dimesylate
- (E)-4-(6-(2-(3-methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine methanesulfonate
- ApiliMod (Mesylate)
- Apilimodmesylate, >98%
- STA-5326 mesylate
- STA5326 mesylate
- STA 5326 MESYLATE; STA5326 MESYLATE; STA-5326 MESYLATE
- STA 5326 mesylate