波生坦羟甲基O-去甲基杂质
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- CAS号:
- 253688-62-9
- 英文名:
- HYDROXY DESMETHYL BOSENTAN
- 英文别名:
- Ro 64-1056;Bosentan Impurity 20;HYDROXY DESMETHYL BOSENTAN;Bosentan Hydroxy methyl O-Desmethyl-Imp;O-Desmethyl Bosentan Hydroxymethyl Analog;Bosentan HydroxyMethyl O-DesMethyl IMpurity;4-(2-Hydroxy-1,1-diMethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyriMidin]-4-yl]benzenesulfonaMide;4-(1-hydroxy-2-methylpropan-2-yl)-N-(6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide;Benzenesulfonamide, 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]-;N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
- 中文名:
- 波生坦羟甲基O-去甲基杂质
- 中文别名:
- 羟去甲波生坦;波生坦杂质15;羟基去甲基波生坦;羟甲基波生坦杂质1;化合物 T11584;羟基O-去甲基波森坦;波生坦羟甲基邻-去甲杂质;波生坦羟甲基O-去甲基杂质;玻色根羟甲基O-脱甲基杂质;波生坦羟基甲基O-去甲基杂质
- CBNumber:
- CB8649131
- 分子式:
- C26H27N5O7S
- 分子量:
- 553.58688
- MOL File:
- 253688-62-9.mol
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波生坦羟甲基O-去甲基杂质化学性质
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熔点:
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>200°C (dec.)
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沸点:
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782.0±70.0 °C(Predicted)
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密度:
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1.426±0.06 g/cm3(Predicted)
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储存条件:
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-20°C Freezer
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溶解度:
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Methanol
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酸度系数(pKa):
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3.81±0.10(Predicted)
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形态:
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Solid
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颜色:
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Light Yellow to Yellow
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InChIKey:
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JXXCMZWROOURSZ-UHFFFAOYSA-N
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SMILES:
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C1(S(NC2C(OC3=CC=CC=C3O)=C(OCCO)N=C(C3=NC=CC=N3)N=2)(=O)=O)=CC=C(C(C)(C)CO)C=C1
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波生坦羟甲基O-去甲基杂质性质、用途与生产工艺
波生坦羟甲基O-去甲基杂质 是一种 Bosentan 代谢物。在肝脏中由细胞色素 P450 酶 CYP2C9 和 CYP3A4 催化产生的。Bosentan 是一种有效的 endothelin-1 (ET) 拮抗剂，在人的 SMC 细胞中，作用于 ETA 和 ETB 受体，Ki 值分别为 4.7 nM 和 95 nM。Bosentan 可用于研究肺动脉高压。
波生坦羟甲基O-去甲基杂质
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/05/22 | HY-135390 | Hydroxy desmethyl Bosentan | | 500 μg | 2112元 |
| 2025/05/22 | HY-135390 | 波生坦羟甲基O-去甲基杂质
Hydroxy desmethyl Bosentan | | 1 mg | 3800元 |
253688-62-9, 波生坦羟甲基O-去甲基杂质 相关搜索:
- Various Metabolites and Impurities
- Metabolites & Impurities
- Heterocycles
- Pharmaceuticals
- Metabolites
- Intermediates & Fine Chemicals
- 抑制剂
- C26H27N5O7S
- 羟甲基波生坦杂质1
- 化合物 HYDROXY DESMETHYL BOSENTAN
- 羟去甲波生坦
- 羟基去甲基波生坦
- 化合物 T11584
- 波生坦杂质15
- 玻色根羟甲基O-脱甲基杂质
- 羟基O-去甲基波森坦
- 波生坦羟甲基邻-去甲杂质
- 波生坦羟基甲基O-去甲基杂质
- 波生坦羟甲基O-去甲基杂质
- 253688-62-9
- 4-(1-hydroxy-2-methylpropan-2-yl)-N-(6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
- Bosentan Impurity 20
- Hydroxy Desmethyl BosentanQ: What is
Hydroxy Desmethyl Bosentan Q: What is the CAS Number of
Hydroxy Desmethyl Bosentan Q: What is the storage condition of
Hydroxy Desmethyl Bosentan Q: What are the applications of
Hydroxy Desmethyl Bosentan
- Benzenesulfonamide, 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]-
- Ro 64-1056
- Bosentan Hydroxy methyl O-Desmethyl-Imp
- N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
- Bosentan HydroxyMethyl O-DesMethyl IMpurity
- 4-(2-Hydroxy-1,1-diMethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyriMidin]-4-yl]benzenesulfonaMide
- HYDROXY DESMETHYL BOSENTAN
- O-Desmethyl Bosentan Hydroxymethyl Analog