ChemicalBook >> CAS DataBase List >>4-(3-fluoro-benzyloxy)-benzaldehyde

4-(3-fluoro-benzyloxy)-benzaldehyde

4-(3-fluoro-benzyloxy)-benzaldehyde structure

CAS No.: 66742-57-2

Chemical Name:: 4-(3-fluoro-benzyloxy)-benzaldehyde

Synonyms: Safinamide Intermediate 1;4-(3-Fluorbenzyloxy)benzaldehyd;Safinamide mesylate Intermediate;Safinamide mesylate Intermediate 1;4-(3-Fluorobenzyloxy)benzaldehyde >4-[(3-fluorophenyl)methoxy]-Benzaldehyde;Benzaldehyde, 4-[(3 -fluorophenyl)Methoxy]-;4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE Intermediate 1;4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE ISO 9001：2015 REACH;4-(3-Fluoro-benzyloxy)benzaldehyde, 4-(3-Fluoro- benzyloxy)benzaldehyde

CBNumber:: CB01010457

Molecular Formula:: C14H11FO2

Molecular Weight:: 230.23

MDL Number:: MFCD02605317

MOL File:: 66742-57-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:14

Product description	Number	Pack Size	Price
4-(3-Fluorobenzyloxy)benzaldehyde >98.0%(GC)	F0943	1g	$89
4-(3-Fluorobenzyloxy)benzaldehyde >98.0%(GC)	F0943	5g	$314
4-(3-Fluorobenzyloxy)benzaldehyde	F588700	1g	$55
4-(3-Fluoro-benzyloxy)-benzaldehyde	018793	500mg	$15
4-(3-Fluoro-benzyloxy)-benzaldehyde	018793	1g	$24
More product size

Request For Quotation

4-(3-fluoro-benzyloxy)-benzaldehyde Properties

Melting point	46.0 to 50.0 °C
Boiling point	265°C/3mmHg(lit.)
Density	1.211±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Methanol
form	Solid:crystalline
color	White to Almost white
InChI	InChI=1S/C14H11FO2/c15-13-3-1-2-12(8-13)10-17-14-6-4-11(9-16)5-7-14/h1-9H,10H2
InChIKey	DNKSIIHRKWTIRH-UHFFFAOYSA-N
SMILES	C(=O)C1=CC=C(OCC2=CC=CC(F)=C2)C=C1
CAS DataBase Reference	66742-57-2
FDA UNII	F835Z6XML4

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
HS Code	2913.00.4000
HazardClass	IRRITANT

4-(3-fluoro-benzyloxy)-benzaldehyde price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	F0943	4-(3-Fluorobenzyloxy)benzaldehyde >98.0%(GC)	66742-57-2	1g	$89	2026-04-30	Buy
TCI Chemical	F0943	4-(3-Fluorobenzyloxy)benzaldehyde >98.0%(GC)	66742-57-2	5g	$314	2026-04-30	Buy
TRC	F588700	4-(3-Fluorobenzyloxy)benzaldehyde	66742-57-2	1g	$55	2021-12-16	Buy
Matrix Scientific	018793	4-(3-Fluoro-benzyloxy)-benzaldehyde	66742-57-2	500mg	$15	2021-12-16	Buy
Matrix Scientific	018793	4-(3-Fluoro-benzyloxy)-benzaldehyde	66742-57-2	1g	$24	2021-12-16	Buy

Product number	Packaging	Price	Buy
F0943	1g	$89	Buy
F0943	5g	$314	Buy
F588700	1g	$55	Buy
018793	500mg	$15	Buy
018793	1g	$24	Buy

4-(3-fluoro-benzyloxy)-benzaldehyde Chemical Properties,Uses,Production

Chemical Properties

4-(3-fluorobenzyloxy)benzaldehyde is white to off-white solid at room temperature and pressure, it is a benzaldehyde derivative, and it is easy to be oxidized by air to produce the corresponding benzoic acid compounds when stored for a long time at room temperature, therefore, it is generally required to be stored under low temperature (2 to 8 degrees).

Uses

4-(3-Fluorobenzyloxy)benzaldehyde is useful for organic reactions and synthesis.

Synthesis

4-(3-fluoro-benzyloxy)-benzaldehyde is synthesized by the reaction of 4-Hydroxybenzaldehyde with 3-fluorobenzyl bromide. 4-Hydroxybenzaldehyde, 3-fluorobenzyl bromide, potassium carbonate, and acetone were sequentially added to a single-neck round bottom flask. Reaction at 60 ° C for 5 h. Cool to room temperature, filter, and collect the filtrate.Purification by direct column chromatography. 4-(3-fluoro-benzyloxy)-benzaldehyde was obtained as a white solid (1.78 g, 94.4%).

References

[1] Patent: WO2009/74478, 2009, A1. Location in patent: Page/Page column 80-81
[2] Patent: WO2009/74478, 2009, A1. Location in patent: Page/Page column 81
[3] Patent: WO2007/147491, 2007, A1. Location in patent: Page/Page column 44-45
[4] Patent: WO2009/74478, 2009, A1. Location in patent: Page/Page column 57-58
[5] Patent: CN106220525, 2016, A. Location in patent: Paragraph 0013; 0014; 0019

4-(3-fluoro-benzyloxy)-benzaldehyde synthesis

Synthesis of 4-(3-fluoro-benzyloxy)-benzaldehyde from (3-FLUOROPHENYL)METHYL METHANESULFONATE and 4-Hydroxybenzaldehyde

4-(3-fluoro-benzyloxy)-benzaldehyde Preparation Products And Raw materials

Raw materials

(3-FLUOROPHENYL)METHYL METHANESULFONATE 4-Hydroxybenzaldehyde 3-Fluorobenzyl chloride 4-Hydroxybenzoic acid 3-Fluorobenzyl bromide

Ethanol Potassium carbonate

1of2

Preparation Products

4-(3-fluoro-benzyloxy)-benzaldehyde Suppliers

Global( 186)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	923	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1319	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Wuhan Chemwish Technology Co., Ltd	58
Shanghai Yingrui Biopharma Co.,Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 4-(3-fluoro-benzyloxy)-benzaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-15	4-(3-fluoro-benzyloxy)-benzaldehyde 66742-57-2	US $0.00-0.00 / kg	1kg	＞98% by HPLC	200kg/month	Zison Pharmaceutical (Shandong) Co., Ltd.
2025-04-04	4-(3-fluoro-benzyloxy)-benzaldehyde 66742-57-2	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2022-02-25	4-(3-fluoro-benzyloxy)-benzaldehyde 66742-57-2	US $0.00 / KG	1KG	98%	100kg	Jinan Ande Pharmaceutical Co.,Ltd.

4-(3-fluoro-benzyloxy)-benzaldehyde
66742-57-2
US $0.00-0.00 / kg
＞98% by HPLC
Zison Pharmaceutical (Shandong) Co., Ltd.

4-(3-fluoro-benzyloxy)-benzaldehyde
66742-57-2
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

4-(3-fluoro-benzyloxy)-benzaldehyde
66742-57-2
US $0.00 / KG
98%
Jinan Ande Pharmaceutical Co.,Ltd.

4-(3-fluoro-benzyloxy)-benzaldehyde Spectrum

4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE(66742-57-2)¹HNMR

66742-57-2(4-(3-fluoro-benzyloxy)-benzaldehyde)Related Search:

3-BROMO-4-[(3-FLUOROBENZYL)OXY]-5-METHOXYBENZALDEHYDE 4-[(3-FLUOROBENZYL)OXY]-3-METHOXYBENZALDEHYDE 4'-(3-FLUOROBENZYLOXY)ACETOPHENONE 4-(3-fluoro-benzyloxy)-benzaldehyde 4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID

4-[(3-FLUOROBENZYL)OXY]BENZENECARBOHYDRAZIDE 3-ETHOXY-4-[(3-FLUOROBENZYL)OXY]BENZALDEHYDE METHYL 4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLATE AURORA 17105 RARECHEM AL BI 1117

AURORA 17115 AURORA 17106 AURORA 17544 AURORA 17119 RARECHEM AL BE 1117

4-[(3,5-DIFLUOROBENZYL)OXY]BENZALDEHYDE SPECS AG-690/15444714 RARECHEM AL BF 1117

1of4

Benzaldehyde, 4-[(3 -fluorophenyl)Methoxy]- 4-[(3-fluorophenyl)methoxy]-Benzaldehyde Safinamide mesylate Intermediate Safinamide mesylate Intermediate 1 4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE Intermediate 1 4-(3-Fluorobenzyloxy)benzaldehyde > Safinamide Intermediate 1 4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE ISO 9001：2015 REACH 4-(3-Fluoro-benzyloxy)benzaldehyde, 4-(3-Fluoro- benzyloxy)benzaldehyde 4-(3-Fluorbenzyloxy)benzaldehyd 66742-57-2 Intermediate