ChemicalBook >> CAS DataBase List >>VICRIVIROC MALEATE
VICRIVIROC MALEATE
- CAS No.
- 599179-03-0
- Chemical Name:
- VICRIVIROC MALEATE
- Synonyms
- SCH-D;CS-1868;Unii-ep3qg127N9;SCH-D (maleate);SCH-417690; SCH-D;VICRIVIROC MALEATE;SCH-417690 (maleate);vicriviroc Maleate salt;VICRIVIROC MALEATE: SCH-D;Vicriviroc Malate(maleate)
- CBNumber:
- CB01011681
- Molecular Formula:
- C32H42F3N5O6
- Molecular Weight:
- 649.7009896
- MDL Number:
- MFCD09833218
- MOL File:
- 599179-03-0.mol
Last updated:2025-01-27 09:38:02
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO : 50 mg/mL (76.96 mM; Need ultrasonic)H2O : 25 mg/mL (38.48 mM; Need ultrasonic and warming) |
| form | Powder |
| color | White to off-white |
| FDA UNII | EP3QG127N9 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H302-H373 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P260-P314-P501-P264-P270-P301+P312-P330-P501 |
VICRIVIROC MALEATE price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2768 | Vicriviroc Maleate ≥98% (HPLC) | 599179-03-0 | 1MG | $94.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2768 | Vicriviroc Maleate ≥98% (HPLC) | 599179-03-0 | 5MG | $381 | 2024-03-01 | Buy |
| Cayman Chemical | 28453 | Vicriviroc (maleate) | 599179-03-0 | 1mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 28453 | Vicriviroc (maleate) | 599179-03-0 | 10mg | $421 | 2024-03-01 | Buy |
| Cayman Chemical | 28453 | Vicriviroc (maleate) | 599179-03-0 | 5mg | $274 | 2024-03-01 | Buy |
VICRIVIROC MALEATE Chemical Properties,Uses,Production
Description
Vicriviroc is a chemokine (C-C motif) receptor 5 (CCR5) antagonist (Ki = 2.5 nM). It selectively inhibits CCR5 over M1 and M2 muscarinic acetylcholine receptors (Kis = >10,000 nM for both) and human-ether-a-go-go (hERG) potassium channels (IC50 = 5.8 μM). Vicriviroc decreases chemotaxis induced by chemokine (C-C motif) ligand 3 (CCL3) in Ba/F3 cells expressing recombinant human CCR5 with an IC50 value of 0.91 nM. It inhibits the replication of 30 R5-tropic HIV-1 clinical isolates in peripheral blood mononuclear cells (PBMCs; EC50s = 0.04-1.4 nM) and reduces viral entry of seven drug-resistant strains of HIV-1 in U87 cells expressing CD4 and CCR5 (EC50s = 8.7-32.9 nM).
Uses
Antiviral, CCR5 antagonist, treatment of autoimmune conditions.
VICRIVIROC MALEATE Preparation Products And Raw materials
Raw materials
Preparation Products
VICRIVIROC MALEATE Suppliers
Global( 65)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9304 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Han Sheng New Material Technology Co.，Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2097 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
View Lastest Price from VICRIVIROC MALEATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Vicriviroc maleate
599179-03-0
|
US $59.00-223.00 / mg | 98.16% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-07-13 | Vicriviroc maleate
599179-03-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | Vicriviroc maleate
599179-03-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Vicriviroc maleate
599179-03-0
- US $59.00-223.00 / mg
- 98.16%
- TargetMol Chemicals Inc.
-
- Vicriviroc maleate
599179-03-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Vicriviroc maleate
599179-03-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
599179-03-0(VICRIVIROC MALEATE)Related Search:
SCH-417690; SCH-D
CS-1868
Vicriviroc Malate(maleate)
Vicriviroc Maleate(SCH 417690)
(4,6-diMethylpyriMidin-5-yl)(4-((S)-4-((R)-2-Methoxy-1-(4-(trifluoroMethyl)phenyl)ethyl)-3-Methylpiperazin-1-yl)-4-Methylpiperidin-1-yl)Methanone fuMarate
vicriviroc Maleate salt
1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate VicrivirocMalate
Vicriviroc maleate
1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate
SCH-D
VICRIVIROC MALEATE
VICRIVIROC MALEATE: SCH-D
Unii-ep3qg127N9
1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate
(4,6-dimethylpyrimidin-5-yl)(4-((S)-4-((R)-2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)methanone maleate
SCH-417690 (maleate)
SCH-D (maleate)
Vicriviroc maleate (SCH-417690 maleate）
Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-, (2Z)-2-butenedioate (1:1) (9CI, ACI)
SCH-D,CCR,Inhibitor,HIV,CC chemokine receptor,SCH417690,inhibit,Vicriviroc maleate,SCH-417690,Vicriviroc,Human immunodeficiency virus,SCH 417690
Vicriviroc maleate, 10 mM in DMSO
599179-03-0
C28H38F3N5O2C4H4O4
C4H4O4C28H38F3N5O2
C32H42F3N5O6