ChemicalBook >> CAS DataBase List >>1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)-

1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)-

1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)- structure

CAS No.: 252278-73-2

Chemical Name:: 1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)-

Synonyms: 674;BN 81674;BN-81,674;1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)-

CBNumber:: CB010790612

Molecular Formula:: C30H38N4

Molecular Weight:: 454.65

MDL Number:

MOL File:: 252278-73-2.mol

Last updated:2025-04-18 09:51:22

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1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)- Properties

Melting point	170-172 °C
Boiling point	690.9±55.0 °C(Predicted)
Density	1.086±0.06 g/cm3(Predicted)
pka	13.46±0.10(Predicted)
FDA UNII	AW987R473Z

1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)- Chemical Properties,Uses,Production

Uses

BN-81674 is a somatostatin analogue and a selective antagonist of the non-peptide human somatostatin sst3 receptor (Ki=0.92 nM). In addition, BN-81674 reversed the inhibition of cyclic AMP accumulation induced by 1 nM somatostatin through the sst3 receptor with an IC50 value of 0.84 nM. BN-81674 can be used in cancer research[1].

IC 50

SSTR3: 0.92 nM (Ki)

References

[1] Poitout L, et al. Identification of potent non-peptide somatostatin antagonists with sst3 selectivity[J]. Journal of medicinal chemistry, 2001, 44(18): 2990-3000. DOI:10.1021/jm0108449

1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)- Suppliers

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TargetMol Chemicals Inc.	58
Wuhan Han Sheng New Material Technology Co.，Ltd	58
Shanghai Tachizaki Biomedical Research Center	58

1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1,1-dipentyl-3-(5-phenyl-1H-imidazol-2-yl)-, (3R)- 674 BN 81674 BN-81,674 252278-73-2