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ChemicalBook >> CAS DataBase List >>431884-01-4

431884-01-4

431884-01-4 Structure
431884-01-4 structure
CAS No.
431884-01-4
Chemical Name:
431884-01-4
Synonyms
N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine;Antimalarial agent 13;Antimalarial agent 13, 10 mM in DMSO;2,4-Quinazolinediamine, N2-(3-chlorophenyl)-N4-(2-furanylmethyl)-;Antimalarial agent13,P. falciparum,Inhibitor,Antimalarial agent 13,inhibit,HepG2,Parasite,Antimalarial agent-13
CBNumber:
CB011398400
Molecular Formula:
C19H15ClN4O
Molecular Weight:
350.8
MDL Number:
MOL File:
431884-01-4.mol
Last updated:2025-04-18 09:51:24
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431884-01-4 Properties

Boiling point 554.6±60.0 °C(Predicted)
Density 1.397±0.06 g/cm3(Predicted)
pka 7.53±0.30(Predicted)

431884-01-4 Chemical Properties,Uses,Production

Uses

Antimalarial agent 13 (Compound 1) is a potent antimalarial agent. Antimalarial agent 13 shows inhibition with EC50 values of 124 nM and 2.5 μM against P. falciparum parasite and HepG2, respectively[1].

References

[1] Gilson PR, et al. Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity. J Med Chem. 2017 Feb 9;60(3):1171-1188. DOI:10.1021/acs.jmedchem.6b01673

431884-01-4 Preparation Products And Raw materials

Raw materials

Preparation Products

431884-01-4 Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32268 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38663 58
Wuhan Han Sheng New Material Technology Co.，Ltd 		+8617798174412 admin01@hsnm.com.cn China 2097 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4720 55
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 3018 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24863 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2672 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd 025-58851090 17714375163 2881759498@qq.com China 13012 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
Wuhan Han Sheng New Material Technology Co.，Ltd 		58
Guangzhou Isun Pharmaceutical Co., Ltd 55
Nantong Hi-Future Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Tachizaki Biomedical Research Center 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd 58

View Lastest Price from 431884-01-4 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Antimalarial agent 13 pictures 2024-11-19 Antimalarial agent 13
431884-01-4
 US $117.00-388.00 / mg 99.15% 10g TargetMol Chemicals Inc.
N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine Antimalarial agent 13 Antimalarial agent13,P. falciparum,Inhibitor,Antimalarial agent 13,inhibit,HepG2,Parasite,Antimalarial agent-13 2,4-Quinazolinediamine, N2-(3-chlorophenyl)-N4-(2-furanylmethyl)- Antimalarial agent 13, 10 mM in DMSO 431884-01-4