Benzolamide
- CAS No.
- 3368-13-6
- Chemical Name:
- Benzolamide
- Synonyms
- W-1803;W 1803;Benzolamide;Benzolamide, 10 mM in DMSO;2-benzenesulfonamido-1,3,4-thiadiazole-5-sulfonamide;5-(Phenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide;5-(phenylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide;1,3,4-Thiadiazole-2-sulfonamide, 5-[(phenylsulfonyl)amino]-;Benzolamide,Inhibitor,Carbonate dehydratase,seizures,CAS3,glaucoma,inhibit,Carbonic Anhydrase
- CBNumber:
- CB01178102
- Molecular Formula:
- C8H8N4O4S3
- Molecular Weight:
- 320.37
- MDL Number:
- MFCD01750412
- MOL File:
- 3368-13-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Benzolamide 99.59% | CS-0066040 | 5mg | $65 |
| Benzolamide 99.59% | CS-0066040 | 10mg | $108 |
| Benzolamide 99.59% | CS-0066040 | 25mg | $217 |
| Benzolamide 99.59% | CS-0066040 | 50mg | $325 |
| Benzolamide 99.59% | CS-0066040 | 5mg | $65 |
| More product size | |||
| Melting point | 239.5°C (rough estimate) |
|---|---|
| Boiling point | 585.9±33.0 °C(Predicted) |
| Density | 1.6772 (rough estimate) |
| refractive index | 1.5690 (estimate) |
| storage temp. | 4°C, protect from light |
| solubility | DMSO : 250 mg/mL (780.35 mM; Need ultrasonic) |
| form | Solid |
| pka | 4.42±0.40(Predicted) |
| color | White to light yellow |
| Water Solubility | 384.4mg/L(25 ºC) |
| FDA UNII | FC5AAH89R5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Benzolamide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0066040 | Benzolamide 99.59% | 3368-13-6 | 5mg | $65 | 2026-06-04 | Buy |
| ChemScene | CS-0066040 | Benzolamide 99.59% | 3368-13-6 | 10mg | $108 | 2026-06-04 | Buy |
| ChemScene | CS-0066040 | Benzolamide 99.59% | 3368-13-6 | 25mg | $217 | 2026-06-04 | Buy |
| ChemScene | CS-0066040 | Benzolamide 99.59% | 3368-13-6 | 50mg | $325 | 2026-06-04 | Buy |
| ChemScene | CS-0066040 | Benzolamide 99.59% | 3368-13-6 | 5mg | $65 | 2026-06-04 | Buy |
Benzolamide Chemical Properties,Uses,Production
Uses
Benzolamide (CL11366) is a potent carbonic anhydrase (CA) inhibitor, with Kis of 15 nM, 9 nM, 94 nM and 78 nM for hCA I, hCA II, EcoCAγ and VchCAγ, respectively. Benzolamide also inhibits CAS3, with a Ki of 54 nM. Benzolamide can be used for the research of glaucoma and seizures[1][2][3].
in vivo
Benzolamide (90 μmol/kg; i.p.) decreases brain pH and suppresses electrographic post-asphyxia seizures in rats[3].
| Animal Model: | Male and female Wistar Han rats (11-day-old)[3] |
| Dosage: | 90 μmol/kg |
| Administration: | A single i.p. |
| Result: | Induced a fast brain acidosis of a comparable magnitude. Suppressed electrographic seizures after asphyxia by slowing down the recovery of brain pH. |
IC 50
CA Ⅱ
References
[1] Prete SD, et, al. Escherichia coli γ-carbonic anhydrase: characterisation and effects of simple aromatic/heterocyclic sulphonamide inhibitors. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1545-1554. DOI:10.1080/14756366.2020.1800670
[2] Vullo D, et, al. Sulfonamide Inhibition Studies of the β-Class Carbonic Anhydrase CAS3 from the Filamentous Ascomycete Sordaria macrospora. Molecules. 2020 Feb 25;25(5):1036. DOI:10.3390/molecules25051036
[3] Pospelov AS, et, al. Carbonic anhydrase inhibitors suppress seizures in a rat model of birth asphyxia. Epilepsia. 2021 Jun 27. DOI:10.1111/epi.16963
Benzolamide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 17714375163 | cfzhang@aikonchem.com | China | 19906 | 55 |
| Sichuan Yuehe Bio-Pharmaceutical Co.,Ltd | 028-82729560 18030702676 | sales@yuehepharm.com | China | 197 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89686 | 60 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49312 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
View Lastest Price from Benzolamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Benzolamide
3368-13-6
|
$47.00-163.00 | 99.31% | 10g | TargetMol Chemicals Inc. |
-
- Benzolamide
3368-13-6
- $47.00-163.00
- 99.31%
- TargetMol Chemicals Inc.
