Ethoxyamine hydrochloride
- CAS No.
- 3332-29-4
- Chemical Name:
- Ethoxyamine hydrochloride
- Synonyms
- O-ETHYLHYDROXYLAMINE HYDROCHLORIDE;EHH;Ethoxylamine Hcl;EthoxyaMine, HCl;EthoxylamineHcl99%;Ethoxyamine hydrochl;2-ETHYLHYDROXYAMINEHCL;O-EthylhydroxylamineHCl;Ethoxyammonium chloride;Ethoxamine hydrochloride
- CBNumber:
- CB0126027
- Molecular Formula:
- C2H8ClNO
- Molecular Weight:
- 97.54
- MDL Number:
- MFCD00012956
- MOL File:
- 3332-29-4.mol
| Product description | Number | Pack Size | Price |
| O-Ethylhydroxylamine hydrochloride 97% | 274992 | 1g | $52.6 |
| O-Ethylhydroxylamine hydrochloride 97% | 274992 | 5g | $176 |
| O-Ethylhydroxylamine Hydrochloride | E0880 | 5G | $26 |
| O-Ethylhydroxylamine Hydrochloride | E0880 | 25G | $77 |
| O-Ethylhydroxylamine hydrochloride for GC derivatization | 43504 | 10g | $449 |
| More product size | |||
| Melting point | 130-133 °C(lit.) |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| Water Solubility | Soluble in water |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| form | Powder, Crystals or Flakes |
| color | Dark gray |
| PH | pH(50g/l, 25℃) : 2.3～2.7 |
| BRN | 3606639 |
| Stability | Hygroscopic |
| InChI | InChI=1S/C2H7NO.ClH/c1-2-4-3;/h2-3H2,1H3;1H |
| InChIKey | NUXCOKIYARRTDC-UHFFFAOYSA-N |
| SMILES | C(C)ON.Cl |
| CAS DataBase Reference | 3332-29-4(CAS DataBase Reference) |
| EPA Substance Registry System | Hydroxylamine, O-ethyl-, hydrochloride (3332-29-4) |
| UNSPSC Code | 41116105 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-34-20/21/22 | |||||||||
| Safety Statements | 26-36-45-36/37/39 | |||||||||
| RIDADR | 3261 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29280000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Ethoxyamine hydrochloride price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 274992 | O-Ethylhydroxylamine hydrochloride 97% | 3332-29-4 | 1g | $52.6 | 2025-07-31 | Buy |
| Sigma-Aldrich | 274992 | O-Ethylhydroxylamine hydrochloride 97% | 3332-29-4 | 5g | $176 | 2025-07-31 | Buy |
| TCI Chemical | E0880 | O-Ethylhydroxylamine Hydrochloride | 3332-29-4 | 5G | $26 | 2025-07-31 | Buy |
| TCI Chemical | E0880 | O-Ethylhydroxylamine Hydrochloride | 3332-29-4 | 25G | $77 | 2025-07-31 | Buy |
| Sigma-Aldrich | 43504 | O-Ethylhydroxylamine hydrochloride for GC derivatization | 3332-29-4 | 10g | $449 | 2025-07-31 | Buy |
Ethoxyamine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
white adhering crystals or crystalline powder
Uses
O-Ethylhydroxylamine hydrochloride was used in the determination of α-hydroxycarbonyl compounds.
reaction suitability
reagent type: derivatization reagent
reaction type: Alkylations
Synthesis
1914-21-2
3332-29-4
1. 500 mg of hydroxyphthalimide (Aldrich) was dissolved in 5 mL of dimethylformamide (DMF) under argon protection. Subsequently, 0.27 mL of ethyl iodide (Aldrich) and 0.5 mL of 1,8-diazabicyclo[5.4.0]undec-7-ene (Aldrich) were added sequentially and slowly added dropwise. 2. The reaction mixture was stirred at 60 °C for 2 h and then cooled to room temperature. The reaction was terminated by addition of 2N hydrochloric acid solution. 3. The reaction solution was diluted with 20 mL of ethyl acetate and subsequently dried over magnesium sulfate and filtered. The filtrate was concentrated under reduced pressure and the residue was purified by silica gel column chromatography using ethyl acetate/hexane (1:5) as eluent to give 518 mg of the target compound (yield: 88%). 4. The above compound was dissolved in 5 mL of dichloromethane, and 0.11 mL of methylhydrazine (TCI) was slowly added at 0 °C. The reaction solution was stirred at room temperature for 2 hours and then cooled to 0°C again. 5. The resulting solid was collected by filtration and 1 mL of 4M dioxane hydrochloride solution (Aldrich) was added to the filtrate, which was filtered and dried to give 263 mg solid (yield: 100%). 6. 10 mg of the resulting solid was dissolved with 44 mg of SAC-0906 in 1 mL of pyridine (Aldrich) under argon protection and stirred at 80 °C for 4 hours. 7. After the reaction solution was cooled to room temperature, it was acidified by adding 2N hydrochloric acid solution and extracted with 20 mL of ether. The organic phase was dried with magnesium sulfate, filtered and concentrated under reduced pressure. 8. The residue was purified by silica gel column chromatography using ethyl acetate/hexane (1:5) as eluent to afford ethoxyamine hydrochloride SAC-1013 (46 mg, yield: 96%). 1H-NMR (300 MHz, CDCl3) δ 5.91-5.76 (m, 2H), 5.34-5.32 (m, 1H), 5.28-5.25 (m, 1H), 5.14 (m, 1H), 4.24-4.10 (m, 3H), 4.04 (q, J = 20.9 Hz, 2H), 3.64-3.48 (m, 1H ), 2.42-0.60 (m, 38H).
References
[1] Patent: US2014/378399, 2014, A1. Location in patent: Paragraph 0097
[2] Farmaco, Edizione Scientifica, 1987, vol. 42, # 10, p. 697 - 708
[3] European Journal of Medicinal Chemistry, 2014, vol. 75, p. 184 - 194
Ethoxyamine hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3998 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 | bj1@bj-chem.com | China | 299 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21595 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29830 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Henan Xiangtong Chemical Co., Ltd. | 86-371-61312303 | info@hnxtchem.com | CHINA | 292 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
View Lastest Price from Ethoxyamine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-06 | Ethoxyamine hydrochloride
3332-29-4
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-06-27 | Ethoxyamine hydrochloride
3332-29-4
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-06-20 | Ethoxyamine hydrochloride
3332-29-4
|
US $20.00-1.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Ethoxyamine hydrochloride
3332-29-4
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Ethoxyamine hydrochloride
3332-29-4
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Ethoxyamine hydrochloride
3332-29-4
- US $20.00-1.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
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