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2-(4-PIPERIDYL)-2-PROPANOL

CAS No.
22990-34-7
Chemical Name:
2-(4-PIPERIDYL)-2-PROPANOL
Synonyms
SKL229;Omaveloxolone Impurity 8;2-(4-PIPERIDYL)-2-PROPANOL;2-(4-Piperidinyl)-2-propanol;2-(4-Piperidyl)-2-propanol>2-(Piperidin-4-yl)propan-2-ol;2-(4-PIPERIDYL)ISOPROPYL ALCOHOL;a,a-DiMethyl-4-piperidineMethanol;4-Piperidinemethanol, α,α-dimethyl-;4-(1-Hydroxy-1-methylethyl)piperidine
CBNumber:
CB0127372
Molecular Formula:
C8H17NO
Molecular Weight:
143.23
MDL Number:
MFCD06797159
MOL File:
22990-34-7.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:45

2-(4-PIPERIDYL)-2-PROPANOL Properties

Melting point 136°C
Boiling point 140-142 °C(Press: 25 Torr)
Density 0.956±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
pka 15.08±0.29(Predicted)
Appearance Off-white to yellow Solid
InChI InChI=1S/C8H17NO/c1-8(2,10)7-3-5-9-6-4-7/h7,9-10H,3-6H2,1-2H3
InChIKey IIXYTWTZMGUQPT-UHFFFAOYSA-N
SMILES C(C1CCNCC1)(O)(C)C
CAS DataBase Reference 22990-34-7

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  2933399990
NFPA 704
0
1 0

2-(4-PIPERIDYL)-2-PROPANOL price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical P1470 2-(4-Piperidyl)-2-propanol >98.0%(GC)(T) 22990-34-7 1g $40 2025-07-31 Buy
TCI Chemical P1470 2-(4-Piperidyl)-2-propanol >98.0%(GC)(T) 22990-34-7 5g $114 2025-07-31 Buy
TCI Chemical P1470 2-(4-Piperidyl)-2-propanol >98.0%(GC)(T) 22990-34-7 25g $402 2025-07-31 Buy
TRC P991883 2-(Piperidin-4-yl)propan-2-ol 22990-34-7 100mg $60 2021-12-16 Buy
SynQuest Laboratories 4H56-1-756 2-(Piperidin-4-yl)propan-2-ol 97.0% 22990-34-7 250mg $75 2021-12-16 Buy
Product number Packaging Price Buy
P1470 1g $40 Buy
P1470 5g $114 Buy
P1470 25g $402 Buy
P991883 100mg $60 Buy
4H56-1-756 250mg $75 Buy

2-(4-PIPERIDYL)-2-PROPANOL Chemical Properties,Uses,Production

Physical Form

Solid

Uses

2-(Piperidin-4-yl)propan-2-ol is a useful research chemical.

Synthesis

1-Piperidinecarboxylic acid, 4-(1-hydroxy-1-methylethyl)-, phenylmethyl ester

160809-39-2

2-(4-PIPERIDYL)-2-PROPANOL

22990-34-7

Benzyl 4-(1-hydroxy-1-methylethyl)piperidine-1-carboxylate (1.786 g, 6.44 mmol) was used as starting material and dissolved in methanol (100 ml) under nitrogen protection. A 10% palladium-carbon catalyst (50% wet, 1.37 g) was added, followed by replacement of the gas in the reaction system with hydrogen at atmospheric pressure. The reaction mixture was stirred at room temperature for overnight reaction. Upon completion of the reaction, the hydrogen in the reaction system was replaced with nitrogen, then the catalyst was removed by filtration and washed with methanol. The filtrate and washings were combined and the solvent was removed by distillation. Finally, the residue was dried under reduced pressure to afford the target product 2-(4-piperidinyl)-2-propanol (922 mg, 6.44 mmol, quantitative yield) as light gray crystals. The product was characterized by 1H-NMR (CDCl3), δ (ppm): 1.18 (6H, s), 1.26-1.42 (3H, m), 1.74-1.80 (2H, m), 2.57-2.64 (2H, m), 3.14-3.22 (2H, m), 3.48 (1H, s).

References

[1] Patent: EP1522540, 2005, A1. Location in patent: Page/Page column 64
[2] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 14, p. 1935 - 1940

160809-39-2
22990-34-7
Synthesis of 2-(4-PIPERIDYL)-2-PROPANOL from 1-Piperidinecarboxylic acid, 4-(1-hydroxy-1-methylethyl)-, phenylmethyl ester
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View Lastest Price from 2-(4-PIPERIDYL)-2-PROPANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(4-PIPERIDYL)-2-PROPANOL pictures 2025-04-04 2-(4-PIPERIDYL)-2-PROPANOL
22990-34-7
US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
2-(4-Piperidyl)-2-propanol pictures 2022-01-27 2-(4-Piperidyl)-2-propanol
22990-34-7
US $0.00 / KG 1KG 97.4% 100 tons Honest Joy Holdings Limited
2-(4-Piperidyl)-2-propanol pictures 2021-07-02 2-(4-Piperidyl)-2-propanol
22990-34-7
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
4-PIPERIDINEMETHANOL, ALPHA,ALPHA-DIMETHYL- 2-(4-PIPERIDYL)-2-PROPANOL 2-(4-PIPERIDYL)ISOPROPYL ALCOHOL 2-(Piperidin-4-yl)propan-2-ol 2-(4-Piperidyl)isopropyl Alcohol 2-(Piperidin-4-yl)propan-2-ol 2-piperidin-4-ylpropan-2-ol(SALTDATA: FREE) a,a-DiMethyl-4-piperidineMethanol 2-(4-Piperidinyl)-2-propanol 2-(4-Piperidyl)-2-propanol> 4-Piperidinemethanol, α,α-dimethyl- SKL229 4-(1-Hydroxy-1-methylethyl)piperidine Omaveloxolone Impurity 8 22990-34-7