ChemicalBook >> CAS DataBase List >>1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)-

1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)-

CAS No.
2767003-71-2
Chemical Name:
1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)-
Synonyms
METTL3-IN-3;1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)-
CBNumber:
CB012779583
Molecular Formula:
C26H28BrFN6O2
Molecular Weight:
555.44
MDL Number:
MOL File:
2767003-71-2.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:22

1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)- Properties

Boiling point 695.2±55.0 °C(Predicted)
Density 1.86±0.1 g/cm3(Predicted)
pka 13.35±0.70(Predicted)

1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)- Chemical Properties,Uses,Production

Uses

METTL3-IN-3 (compound 11) is a polyheterocyclic compound, acts as METTL3 inhibitor[1].

References

[1] Blackaby WP, et al. Preparation of polyheterocyclic compounds as METTL3 inhibitors: World Intellectual Property Organization, WO2021111124[P]. 2021-06-10.
[2] Zeng C, et al. Roles of METTL3 in cancer: mechanisms and therapeutic targeting. J Hematol Oncol. 2020 Aug 27;13(1):117. DOI:10.1186/s13045-020-00951-w

1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)- Preparation Products And Raw materials

Raw materials

Preparation Products

1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)- Suppliers

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TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
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2767003-71-2(1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)-)Related Search:

1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)- METTL3-IN-3 2767003-71-2