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(R)-N-BOC-Propargylglycine

(R)-N-BOC-Propargylglycine structure

CAS No.: 63039-46-3

Chemical Name:: (R)-N-BOC-Propargylglycine

Synonyms: BOC-D-PROPARGYLGLYCINE;(R)-N-(TERT-BUTOXYCARBONYL)-PROPARGYLGLYCINE;Boc-D-propraglycine;RARECHEM BK PT 0259;Boc-D-Propargyl-Gly-OH;Boc-D-Gly(propargyl)-OH;N-Boc-D-Propargylglycine;Boc-(R)-2-Propargylglycine;(R)-N-BOC-PROPARGYLGLYCINE;Boc-D-Propargylglycine ,98%

CBNumber:: CB0138392

Molecular Formula:: C10H15NO4

Molecular Weight:: 213.23

MDL Number:: MFCD01320886

MOL File:: 63039-46-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:18:05

Product description	Number	Pack Size	Price
Boc-D-Propargylglycine Asreported	264335	250mg	$492
Boc-D-Propargylglycine Asreported	264335	500mg	$708
Boc-D-Propargylglycine Asreported	264335	1g	$1007
Boc-D-Propargylglycine Asreported	264335	2g	$1449
Boc-D-Propargylglycine Asreported	264335	5g	$2114
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(R)-N-BOC-Propargylglycine Properties

Melting point	86-88°
Boiling point	353.22°C (rough estimate)
Density	1.2177 (rough estimate)
refractive index	1.4368 (estimate)
storage temp.	2-8°C
pka	3.53±0.10(Predicted)
form	Crystalline Powder
color	Off-white to light beige
optical activity	-32.6364°(C=1.1311 g/100ml CHCL3)
InChI	InChI=1S/C10H15NO4/c1-5-6-7(8(12)13)11-9(14)15-10(2,3)4/h1,7H,6H2,2-4H3,(H,11,14)(H,12,13)/t7-/m1/s1
InChIKey	AMKHAJIFPHJYMH-SSDOTTSWSA-N
SMILES	C(O)(=O)[C@H](NC(OC(C)(C)C)=O)CC#C
CAS DataBase Reference	63039-46-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332

Precautionary statements

P260-P280-P301+P312-P302+P352-P304+P340-P361+P364

Hazard Codes

Safety Statements

24/25

HS Code

29224985

NFPA 704

	1
2		0

(R)-N-BOC-Propargylglycine price More Price(81)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	264335	Boc-D-Propargylglycine Asreported	63039-46-3	250mg	$492	2026-06-03	Buy
Usbiological	264335	Boc-D-Propargylglycine Asreported	63039-46-3	500mg	$708	2026-06-03	Buy
Usbiological	264335	Boc-D-Propargylglycine Asreported	63039-46-3	1g	$1007	2026-06-03	Buy
Usbiological	264335	Boc-D-Propargylglycine Asreported	63039-46-3	2g	$1449	2026-06-03	Buy
Usbiological	264335	Boc-D-Propargylglycine Asreported	63039-46-3	5g	$2114	2026-06-03	Buy

Product number	Packaging	Price	Buy
264335	250mg	$492	Buy
264335	500mg	$708	Buy
264335	1g	$1007	Buy
264335	2g	$1449	Buy
264335	5g	$2114	Buy

(R)-N-BOC-Propargylglycine Chemical Properties,Uses,Production

Chemical Properties

off-white to light beige crystalline powder

Uses

(R)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid is a Glycine (HY-Y0966) derivative[1]. (R)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Synthesis

24424-99-5

23235-01-0

61172-66-5

Step 5: Preparation of (R)-2-((tert-butoxycarbonyl)amino)pent-4-ynoic acid L-alkynylglycine (10 g) [prepared according to Schwyzer et al, Helv. Chim. Acta, 59, 2181 (1976)] was suspended in tetrahydrofuran (30 mL). To this suspension, water (30 mL), potassium carbonate (36.7 g) and di-tert-butyl dicarbonate (21.9 g) were added sequentially. Subsequently, additional water was added to completely dissolve the mixture and the resulting solution was stirred for 12 hours at room temperature. Upon completion of the reaction, the organic solvent was removed by evaporation. The remaining aqueous phase was washed with ether and then acidified with 1N aqueous citric acid to pH 3. The acidified aqueous phase was extracted with dichloromethane, and the organic phases were combined and the solvent was removed by evaporation to afford (R)-2-((tert-butoxycarbonyl)amino)pent-4-ynoic acid (18.9 g, 97% yield), and the product was ready to use in subsequent reactions without further purification.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

(R)-N-BOC-Propargylglycine Preparation Products And Raw materials

Raw materials

4-Pentynoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, phenylmethyl ester, (1S)- Di-tert-butyl dicarbonate L-Propargylglycine Tetrahydrofuran Water

Potassium carbonate

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Preparation Products

(R)-N-BOC-Propargylglycine Suppliers

Global( 180)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2994	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29792	58
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
Hubei Ipure Biology Co., Ltd	+8618062405514	ada@ipurechemical.com	China	10236	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34563	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	86 18062405514 18062405514	ada@ipurechemical.com	CHINA	3461	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58

Supplier	Advantage
GenicBio Limited	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shanghai Boc Chemical Co., Ltd.	58
Hubei Ipure Biology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	58
GL Biochem (Shanghai) Ltd.	58

View Lastest Price from (R)-N-BOC-Propargylglycine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-03	Boc-D-Propargylglycine 63039-46-3		1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2021-08-11	(R)-N-BOC-Propargylglycine 63039-46-3	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2019-12-25	(R)-N-BOC-Propargylglycine 63039-46-3	$1.00	1KG	99%	200kg	Career Henan Chemical Co

Boc-D-Propargylglycine
63039-46-3
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

(R)-N-BOC-Propargylglycine
63039-46-3
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

(R)-N-BOC-Propargylglycine
63039-46-3
$1.00
99%
Career Henan Chemical Co

(R)-N-BOC-Propargylglycine Spectrum

(R)-N-BOC-Propargylglycine(63039-46-3)¹HNMR

63039-46-3((R)-N-BOC-Propargylglycine)Related Search:

L-Propargylglycine (R)-METHYL-2-BOC-AMINO-4-PENTENOIC ACID METHYL-2-BOC-AMINO-4-PENTENOIC ACID DL-PROPARGYLGLYCINE (S)-N-BOC-Propargylglycine

(R)-2-(((benzyloxy)carbonyl)aMino)pent-4-ynoic acid Cyclohexylamine L-Propargylglycine HCL (R)-2-aminopent-4-ynoic acid (R)-N-BOC-Propargylglycine

4-Pentyn-1-ol D-PROPARGYLGLYCINE 4-Fluorocinnamic acid 4-PENTYNOIC ACID DL-PROPARGYL-GLY-OH

BOC-(R)-ALPHA-PROPYNYL-PROLINE Carbamic acid, [(1R)-1-(hydroxymethyl)-2-propynyl]-, 1,1-dimethylethyl ester BOC-D-PRA-OH DCHA

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(R)-(1-Hydroxymethyl-but-3-ynyl)-carbamic acid tert-butyl ester (R)-2-tert-Butoxycarbonylamino-pent-4-ynoic acid Boc-D-Propargylglycine.DCHA (R)-N-BOC-PROPARGYLGLYCINE, 95%, 98% EE (R)-N-BOC-Propargylglycine, 98% ee (R)-N-BOC-Propargylglycine(R)-N-tert-Butoxycarbonyl-2-amino-4-pentynoic acid (R)-N-TERT-BUTOXYCARBONYL-2-AMINO-4-PENTYNOIC Boc-D-Propargylglycine ,98% Boc-D-Propargylglycine Boc-D-Propargylglycine Boc-D-propraglycine (R)-2-Boc-AMino-4-pentynoic acid Boc-(R)-2-Propargylglycine Boc-D-Propargyl-Gly-OH 2-[[4-[(2-methylpropan-2-yl)oxy]-4-oxobut-2-ynyl]amino]acetic acid (2R)-2-{[(tert-butoxy)carbonyl]amino}pent-4-ynoic acid D-2-Propargylglycine, N-BOC protected 97% (R)-N-TERT-BUTOXYCARBONYL-2-AMINO-4-PENTYNOIC ACID (R)-N-BOC-PROPARGYLGLYCINE RARECHEM BK PT 0259 Boc-D-Gly(propargyl)-OH (R)-N-boc-Propargylglycine(e.e.) N-TERT-BUTOXYCARBONYL-D-PROPARGYL GLYCINE N-BOC-2-PROPARGYL-D-GLYCINE BOC-2-PROPARGYL-D-GLYCINOL D-2-Propargylglycine, N-BOC protected (Tert-Butoxy)Carbonyl D-Pra-OH Boc-D-Pra-OH Boc-D-Propargylglycine 4-Pentynoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)- N-Boc-2-propargyl-D-glycine,95% (R)-N-BOC-Propargylglycine USP/EP/BP (R)-N-Boc-2-propargyl-glycine N-Boc-D-Propargylglycine (R)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid - [B90819] (R)-N-(TERT-BUTOXYCARBONYL)-PROPARGYLGLYCINE BOC-D-PROPARGYLGLYCINE 63039-46-3 Unusual amino acids Amino Acids Amino Acid Derivatives