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HSD17B13-IN-30

CAS No.
2770246-58-5
Chemical Name:
HSD17B13-IN-30
Synonyms
HSD17B13-IN-30;Benzamide, 3,5-dichloro-N-[3,4-dihydro-2-methyl-4-oxo-3-[[2-(trifluoromethoxy)phenyl]methyl]-5-quinazolinyl]-4-hydroxy-
CBNumber:
CB014270035
Molecular Formula:
C24H16Cl2F3N3O4
Molecular Weight:
538.3
MDL Number:
MOL File:
2770246-58-5.mol
Last updated:2025-08-23 08:01:07

HSD17B13-IN-30 Properties

Density 1.518±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)

HSD17B13-IN-30 Chemical Properties, Uses, Production

Uses

HSD17B13-IN-30 (compound 64) is a ppotent inhibitor of hydroxysteroid 17-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM estradiol as substrates. HSD17B13-IN-30 plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis)[1].

References

[1] Inipharm, Inc. Preparation of dichlorophenol derivatives as HSD17B13 inhibitors and uses thereof. World Intellectual Property Organization, WO2022103960 A1 2022-05-19

HSD17B13-IN-30 Preparation Products And Raw materials

Raw materials

Preparation Products

HSD17B13-IN-30 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
HSD17B13-IN-30 Benzamide, 3,5-dichloro-N-[3,4-dihydro-2-methyl-4-oxo-3-[[2-(trifluoromethoxy)phenyl]methyl]-5-quinazolinyl]-4-hydroxy- 2770246-58-5