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Thalidomide-NH-amido-PEG4-C2-NH2

Thalidomide-NH-amido-PEG4-C2-NH2 structure

CAS No.: 2653336-34-4

Chemical Name:: Thalidomide-NH-amido-PEG4-C2-NH2

Synonyms: Pomalidomide-NH amido-PEG4-NH2;Thalidomide-NH-amido-PEG4-C2-NH2;Acetamide, N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

CBNumber:: CB014293597

Molecular Formula:: C25H35N5O9

Molecular Weight:: 549.57

MDL Number:

MOL File:: 2653336-34-4.mol

Last updated:2025-05-31 08:02:06

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Thalidomide-NH-amido-PEG4-C2-NH2 Properties

Boiling point	827.295±65.00 °C(Press: 760.00 Torr)(predicted)
Density	1.348±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	10.733±0.40(predicted)

Thalidomide-NH-amido-PEG4-C2-NH2 Chemical Properties, Uses, Production

Uses

Thalidomide-NH-amido-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Thalidomide-NH-amido-PEG4-C2-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

Thalidomide-NH-amido-PEG4-C2-NH2 Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
Xi'an Confluore Biological Technology Co., Ltd.	+86-156-80926068 +86-15680926068	1924344760@qq.com	China	4229	58
Shanghai Yanfen Biochemical Technology Co.,LTD	17721070236	yanfen2026@126.com	China	2198	58
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58

Supplier	Advantage
Xi'an Confluore Biological Technology Co., Ltd.	58
Shanghai Yanfen Biochemical Technology Co.,LTD	58
TargetMol	58

2653336-34-4 (Thalidomide-NH-amido-PEG4-C2-NH2) Related Search:

(2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Thalidomide-NH-PEG2-C2-NH2 hydrochloride Pomalidomide-PEG3-N3 CAS:2722697-82-5 (S,R,S)-AHPC-Me-C6-NH2

2,6-Piperidinedione, 3-[4-[[2-(2-aminoethoxy)ethyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, hydrochloride (1:2)

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Thalidomide-NH-amido-PEG4-C2-NH2 Pomalidomide-NH amido-PEG4-NH2 Acetamide, N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 2653336-34-4