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Trimeprazine

CAS No.
84-96-8
Chemical Name:
Trimeprazine
Synonyms
Teralen;Teralene;Alimezine;Bayer 1219;ALIMENAZINE;alimemazine;TRIMEPRAZINE;Trimeperazine;dl-Trimeprazine;Methylpromazine
CBNumber:
CB0146078
Molecular Formula:
C18H22N2S
Molecular Weight:
298.45
MDL Number:
MFCD00242597
MOL File:
84-96-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-21 10:31:43
Product description Number Pack Size Price
TRIMEPRAZINE 95.00% API0009048 25G $2122.31
Trimeprazine-d6(Alimemazine-d6)HCl T-7860 10mg $1800
More product size

Trimeprazine Properties

Melting point 68°C
Boiling point bp0.3 150-175°
Density 1.1163 (rough estimate)
refractive index 1.6000 (estimate)
pka pKa 9.00 (Uncertain)
Water Solubility 0.942 mg/L
CAS DataBase Reference 84-96-8
FDA UNII 76H78MJJ52
ATC code R06AD01
NIST Chemistry Reference Trimeprazine(84-96-8)

SAFETY

Risk and Safety Statements

Trimeprazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0009048 TRIMEPRAZINE 95.00% 84-96-8 25G $2122.31 2021-12-16 Buy
Chemtos T-7860 Trimeprazine-d6(Alimemazine-d6)HCl 84-96-8 10mg $1800 2021-12-16 Buy
Product number Packaging Price Buy
API0009048 25G $2122.31 Buy
T-7860 10mg $1800 Buy

Trimeprazine Chemical Properties,Uses,Production

Originator

Temaril,SKF,US,1958

Uses

antipruritic

Uses

Trimeprazine is used for treating itching during dermatitis of both allergic and nonallergic origin.

Definition

ChEBI: Trimeprazine is a member of phenothiazines.

Manufacturing Process

95% sodamide (2.77 grams) is added to a solution of phenthiazine (9.6 grams) in xylene (140 cc) at a temperature of 130°C and the mixture is heated with reflux for 2 hours.
A 0.61 N solution (90 cc) of 1-chloro-2-methyl-3-dimethylaminopropane in xylene is then added over 50 minutes and heating with reflux is continued for 20 hours. After cooling, the mixture is treated with water (40 cc) and N methanesulfonic acid (70 cc). The aqueous layer is washed with ether, treated with aqueous sodium hydroxide (density = 1.33; 10 cc) and extracted with ether.
The extract is dried over potassium carbonate and evaporated and the residue is distilled in vacuo. 3-(10-phenthiazinyl)-2-methyl-1-dimethylaminopropane (12.6 grams) is collected, distilling between 150° and 175°C under a pressure of about 0.3 mm Hg. By dissolving this base in acetone and adding ethereal hydrogen chloride, a hydrochloride is obtained, MP 216° to 217°C.

brand name

Temaril (Allergan).

Therapeutic Function

Antipruritic

Trimeprazine Preparation Products And Raw materials

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040 1056@dideu.com China 3982 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39040 58
Qingdao Dexin Chemical Co., Ltd
+86-15553333686 15553333686@qq.com China 3113 58
Hebei Chuanghai Biotechnology Co., Ltd
+86-15350571055 Sibel@chuanghaibio.com China 6085 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19957 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
+8618950047208 ellena@amitychem.com China 43416 58

View Lastest Price from Trimeprazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Alimemazine pictures 2026-04-21 Alimemazine
84-96-8
US $1520.00-1980.00 / mg 10g TargetMol Chemicals Inc.
Trimeprazine pictures 2026-02-02 Trimeprazine
84-96-8
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
Alimemazine pictures 2025-10-28 Alimemazine
84-96-8
US $1520.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • Alimemazine pictures
  • Alimemazine
    84-96-8
  • US $1520.00-1980.00 / mg
  • TargetMol Chemicals Inc.
  • Trimeprazine pictures
  • Trimeprazine
    84-96-8
  • US $1.00-1.00 / KG
  • 99%
  • Shaanxi Dideu Medichem Co. Ltd
  • Alimemazine pictures
  • Alimemazine
    84-96-8
  • US $1520.00-1980.00 / mg
  • TargetMol Chemicals Inc.
n,n,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl- dl-Trimeprazine Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]- (6CI, 8CI) Teralene ALIMENAZINE Trimeprazine (base and/or unspecified salts) alimemazine 10-[2-Methyl-3-(dimethylamino)propyl]phenothiazine 10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine 10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl- Alimezine Bayer 1219 Methylpromazine N,N,2-Trimethyl-3-(10H-phenothiazin-10-yl)-1-propanamine Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]- Teralen Trimeperazine Alimemazine-d6 MALEATE SALT TRIMEPRAZINE dimethyl-(2-methyl-3-phenothiazin-10-yl-propyl)amine N,N,2-triMethyl-3-(10H-phenothiazin-10-yl)propan-1-aMine 10H-Phenothiazine-10-propanaMine,N,N,b-triMethyl- Trimeprazine USP/EP/BP 84-96-8 84-86-8 C18H22N2S TEMARIL