5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE
- CAS No.
- 94805-51-3
- Chemical Name:
- 5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE
- Synonyms
- 2-hydroxy-4-cyanopyridine;2,3-DIHYDRO-5-FLUORO(1H)-INDOLE;2-hydroxypyridine-4-carbonitrile;1,2-dihydro-2-oxo-4-Pyridinecarbonitrile;4-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-;4-Pyridinecarbonitrile,1,2-dihydro-2-oxo-(9CI);5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE ISO 9001：2015 REACH
- CBNumber:
- CB0149165
- Molecular Formula:
- C6H4N2O
- Molecular Weight:
- 120.11
- MDL Number:
- MFCD04037920
- MOL File:
- 94805-51-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS07,GHS08,GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H332-H314-H341-H225 |
| Precautionary statements | P501-P261-P202-P240-P210-P233-P201-P243-P241-P242-P271-P264-P280-P370+P378-P308+P313-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37 |
| Hazard Note | Irritant |
5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | H480550 | 2-Hydroxyisonicotinonitrile | 94805-51-3 | 500mg | $65 | 2021-12-16 | Buy |
| AK Scientific | V9473 | 4-Cyano-2(1H)-pyridinone | 94805-51-3 | 250mg | $89 | 2021-12-16 | Buy |
| Matrix Scientific | 009317 | 2-Hydroxyisonicotinonitrile | 94805-51-3 | 1g | $51 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H37-1-4Q | 2-Hydroxyisonicotinonitrile | 94805-51-3 | 1g | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 009317 | 2-Hydroxyisonicotinonitrile | 94805-51-3 | 5g | $190 | 2021-12-16 | Buy |
5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE Chemical Properties,Uses,Production
Synthesis
42182-27-4
94805-51-3
General procedure for the synthesis of 2-oxo-1,2-dihydropyridine-4-carbonitrile from 2-amino-4-cyanopyridine: Sodium nitrite (NaNO2, 0.99 g, 14.3 mmol) was added in batches to a well-stirred 2-amino-4-cyanopyridine (0.96 g, 8.1 mmol) dissolved in concentrated sulfuric acid (H2SO4, 1.2 mL) and water (11 mL) in a premixed solution. During the reaction, the temperature of the reaction mixture was maintained between 0-5 °C and strictly controlled in the range of 5 ± 5 °C. With the release of nitrogen (N2), the originally clarified solution gradually became turbid. The mixture was slowly warmed to room temperature with stirring, followed by reflux heating in a water bath for 30 min and finally cooled to room temperature. The solid product formed was collected by filtration, washed with water (H2O) and dried under vacuum to afford the target product 2-oxo-1,2-dihydropyridine-4-carbonitrile (0.9 g, 92% yield) as a colorless solid. The structure of the product was confirmed by 1H NMR (DMSO-d6): δ 8.21 (d, 1H, J = 2.4 Hz), 7.61 (dd, 1H, J = 2.4, 9.6 Hz), 6.38 (d, 1H, J = 9.6 Hz), 3.3 (broad peak, 1H + 2H2O).
References
[1] Patent: WO2014/63199, 2014, A1. Location in patent: Page/Page column 59
5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7927 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
View Lastest Price from 5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE
94805-51-3
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd |
-
- 5-FLUORO-2,3-DIHYDRO-(1H)-INDOLE
94805-51-3
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
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