2,4-Dichloro-6-methoxyquinazoline
- CAS No.
- 105763-77-7
- Chemical Name:
- 2,4-Dichloro-6-methoxyquinazoline
- Synonyms
- 2,4-Dichloro-6-methoxyqui...;6-Methoxy-2,4-dichloroquinazoline;2,4-Dichloro-6-methoxyquinazoline;Quinazoline,2,4-dichloro-6-methoxy-
- CBNumber:
- CB01504497
- Molecular Formula:
- C9H6Cl2N2O
- Molecular Weight:
- 229.06
- MDL Number:
- MFCD09954880
- MOL File:
- 105763-77-7.mol
| Product description | Number | Pack Size | Price |
| 2,4-Dichloro-6-methoxyquinazoline | D438438 | 100mg | $60 |
| 2,4-Dichloro-6-methoxyquinazoline | X8777 | 1g | $211 |
| 2,4-Dichloro-6-methoxyquinazoline | 4H56-5-0V | 1g | $525 |
| 2,4-Dichloro-6-methoxyquinazoline 95% | 057335 | 1g | $849 |
| 2,4-DICHLORO-6-METHOXYQUINAZOLINE 95.00% | HCH0049826 | 1G | $1510.74 |
| More product size | |||
| Melting point | 171 °C |
|---|---|
| Boiling point | 315.9±24.0 °C(Predicted) |
| Density | 1.450 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -0.67±0.30(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChI | InChI=1S/C9H6Cl2N2O/c1-14-5-2-3-7-6(4-5)8(10)13-9(11)12-7/h2-4H,1H3 |
| InChIKey | WEAMQTSRMCCGSJ-UHFFFAOYSA-N |
| SMILES | N1=C2C(C=C(OC)C=C2)=C(Cl)N=C1Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN2811 |
| HazardClass | IRRITANT |
2,4-Dichloro-6-methoxyquinazoline price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D438438 | 2,4-Dichloro-6-methoxyquinazoline | 105763-77-7 | 100mg | $60 | 2021-12-16 | Buy |
| AK Scientific | X8777 | 2,4-Dichloro-6-methoxyquinazoline | 105763-77-7 | 1g | $211 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H56-5-0V | 2,4-Dichloro-6-methoxyquinazoline | 105763-77-7 | 1g | $525 | 2021-12-16 | Buy |
| Matrix Scientific | 057335 | 2,4-Dichloro-6-methoxyquinazoline 95% | 105763-77-7 | 1g | $849 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0049826 | 2,4-DICHLORO-6-METHOXYQUINAZOLINE 95.00% | 105763-77-7 | 1G | $1510.74 | 2021-12-16 | Buy |
2,4-Dichloro-6-methoxyquinazoline Chemical Properties,Uses,Production
Synthesis
32618-84-1
105763-77-7
Method F1: Synthesis of 2,4-dichloro-6-methoxyquinazoline (xa) To a mixture of 6-methoxyquinazoline-2,4(1H,3H)-dione (9.63 g, 50.2 mmol) and phosphorus trichloride (POCl3, 150 mL) was added N,N-dimethylaniline (0.5 mL). The reaction mixture was stirred at 120 °C for 2 hours. Upon completion of the reaction, the excess POCl3 was removed by distillation under reduced pressure. the residue was slowly poured into ice water and the pH was adjusted to about 7 by slowly adding saturated sodium bicarbonate (NaHCO3) solution at 0 °C, where a precipitate was formed. The precipitate was collected and dried under vacuum to give 2,4-dichloro-6-methoxyquinazoline (11.2 g, 98% yield) as a brown solid. LCMS m/z = 229.1, 231.0 [M + 1] (Method B) (retention time = 1.87 min). 1H-NMR (400 MHz, DMSO-d6): δ 7.89 (d, J = 9.2 Hz, 1H), 7.71 (dd, J = 8.8, 2.4 Hz, 1H), 7.38 (d, J = 1.6 Hz, 1H), 3.91 (s, 3H).
References
[1] Patent: US2015/307477, 2015, A1. Location in patent: Paragraph 1497
[2] Patent: JP6121658, 2017, B2. Location in patent: Paragraph 1096; 1099
[3] Patent: US2010/68197, 2010, A1. Location in patent: Page/Page column 17
[4] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 11, p. 2439 - 2444
[5] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 24, p. 7717 - 7727
2,4-Dichloro-6-methoxyquinazoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5661 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
View Lastest Price from 2,4-Dichloro-6-methoxyquinazoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-09 | 2,4-Dichloro-6-methoxyquinazoline
105763-77-7
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 2,4-Dichloro-6-methoxyquinazoline
105763-77-7
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
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