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Fluoroiodomethane

CAS No.
373-53-5
Chemical Name:
Fluoroiodomethane
Synonyms
Fluoromethyl iodide;fluoro-iodo-methane;Fluor(iod)methan;Fluoroiodomethane 95%;Methane, fluoroiodo- (6CI,8CI,9CI);Fluoroiodomethane (ca. 2mol/L in Acetonitrile)
CBNumber:
CB01512724
Molecular Formula:
CH2FI
Molecular Weight:
159.93
MDL Number:
MFCD12404952
MOL File:
373-53-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:22:55
Product description Number Pack Size Price
Fluoroiodomethane (ca. 2mol/L in Acetonitrile) F1279 5ML $268
Fluoroiodomethane TRC-F591955-5G 5g $856
Fluoroiodomethane TRC-F591955-1G 1g $286
Fluoroiodomethane TRC-F591955-10G 10g $1488
Fluoroiodomethane FF77065 0.5g $347.39
More product size

Fluoroiodomethane Properties

Boiling point 53.4℃
Density 2.366 g/cm3 (20 ºC)
refractive index 1.491 (589.3 nm 20℃)
form clear liquid
color Colorless to Light yellow
Stability Volatile
InChI InChI=1S/CH2FI/c2-1-3/h1H2
InChIKey XGVXNTVBGYLJIR-UHFFFAOYSA-N
SMILES C(F)I
CAS DataBase Reference 373-53-5
FDA UNII F4DZ382EN9

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H319-H335-H301+H311+H331-H315
Precautionary statements  P260-P280-P312
HS Code  2903798000
NFPA 704
2
3 0

Fluoroiodomethane price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F1279 Fluoroiodomethane (ca. 2mol/L in Acetonitrile) 373-53-5 5ML $268 2026-04-30 Buy
TRC TRC-F591955-5G Fluoroiodomethane 373-53-5 5g $856 2026-06-03 Buy
TRC TRC-F591955-1G Fluoroiodomethane 373-53-5 1g $286 2026-06-03 Buy
TRC TRC-F591955-10G Fluoroiodomethane 373-53-5 10g $1488 2026-06-03 Buy
Biosynth FF77065 Fluoroiodomethane 373-53-5 0.5g $347.39 2026-06-04 Buy
Product number Packaging Price Buy
F1279 5ML $268 Buy
TRC-F591955-5G 5g $856 Buy
TRC-F591955-1G 1g $286 Buy
TRC-F591955-10G 10g $1488 Buy
FF77065 0.5g $347.39 Buy

Fluoroiodomethane Chemical Properties,Uses,Production

Uses

Fluoroiodomethane is an synthetic precursor for the fluoromethylation of radiopharmaceuticals.

Properties and Applications

Fluoroiodomethane is a commercially available liquid with a boiling point of 53.4 °C. This reagent is easy to handle and represents a non-ozone-depleting alternative to the frequently used CFC (chlorofluorocarbons) and HBFC (hydrobromofluorocarbons). This reagent is featured by two carbon–halogen bonds (C–I and C–F) characterized by diverse reactivity. The bond dissociation energy (BDE) of C–I (233 kJ mol1) compared to that of the C–F bond (460 kJ mol1) enables a selective activation of CH2FI for multiple pathways delivering the fluoromethyl fragment unit. Indeed, the C–I bond can be engaged in lithium exchange protocols, transition-metal catalyzed reactions, nucleophilic substitutions, and radical pathways[1].

References

[1] Marco Colella . “The synthetic versatility of fluoroiodomethane: recent applications as monofluoromethylation platform.” Organic Biomolecular Chemistry 20 23 (2022): Pages 4669-4680.

593-70-4
373-53-5
Synthesis of Fluoroiodomethane from Chlorofluoromethane
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  • Jan 9,2024

View Lastest Price from Fluoroiodomethane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
fluoro-iodo-methane pictures 2025-09-25 fluoro-iodo-methane
373-53-5
$1.00-101.00 1KG 99% Henan Fengda Chemical Co., Ltd
Fluoroiodomethane pictures 2024-06-13 Fluoroiodomethane
373-53-5
$1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
Fluoromethyl iodide Fluoroiodomethane 95% Methane, fluoroiodo- (6CI,8CI,9CI) Fluoroiodomethane (ca. 2mol/L in Acetonitrile) Fluor(iod)methan fluoro-iodo-methane 373-53-5 CH2FI