5-bromothiophene-3-carboxylic acid
- CAS No.
- 100523-84-0
- Chemical Name:
- 5-bromothiophene-3-carboxylic acid
- Synonyms
- 5-BroMo-3-thiophenecarboxylic acid;EA159;5-Bromothiophene-3-carboxylicaci;2-Bromothiophene-4-carboxylic acid;5-bromothiophene-3-carboxylic acid;3-Thiophenecarboxylic acid, 5-broMo-;5-Bromothiophene-3-carboxylic acid 97+%;5-Bromothiophene-3-carboxylic acid≥ 97% (HPLC);5-bromothiophene-3-carboxylic acid ISO 9001:2015 REACH
- CBNumber:
- CB01529504
- Molecular Formula:
- C5H3BrO2S
- Molecular Weight:
- 207.05
- MDL Number:
- MFCD08695074
- MOL File:
- 100523-84-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-bromothiophene-3-carboxylic acid 97% | 774227 | 1g | $218 |
| 5-BROMOTHIOPHENE-3-CARBOXYLIC ACID 97% | 55810 | 1G | $26 |
| 5-BROMOTHIOPHENE-3-CARBOXYLIC ACID 97% | 55810 | 5G | $110 |
| 5-BROMOTHIOPHENE-3-CARBOXYLIC ACID 97% | 55810 | 25G | $450 |
| 5-Bromothiophene-3-carboxylic acid ≥97%(HPLC) | 30711 | 1G | $72.31 |
| More product size | |||
| Melting point | 140-144°C |
|---|---|
| Boiling point | 318.9±27.0 °C(Predicted) |
| Density | 1.923±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | solid |
| pka | 3.82±0.10(Predicted) |
| color | Off-white |
| InChI | InChI=1S/C5H3BrO2S/c6-4-1-3(2-9-4)5(7)8/h1-2H,(H,7,8) |
| InChIKey | YCNXGPMGMAKDPM-UHFFFAOYSA-N |
| SMILES | C1SC(Br)=CC=1C(O)=O |
| CAS DataBase Reference | 100523-84-0 |
| UNSPSC Code | 12352106 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| HS Code | 2934999090 |
| Storage Class | 11 - Combustible Solids |
5-bromothiophene-3-carboxylic acid price More Price(83)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 774227 | 5-bromothiophene-3-carboxylic acid 97% | 100523-84-0 | 1g | $218 | 2023-06-20 | Buy |
| AstaTech | 55810 | 5-BROMOTHIOPHENE-3-CARBOXYLIC ACID 97% | 100523-84-0 | 1G | $26 | 2026-04-30 | Buy |
| AstaTech | 55810 | 5-BROMOTHIOPHENE-3-CARBOXYLIC ACID 97% | 100523-84-0 | 5G | $110 | 2026-04-30 | Buy |
| AstaTech | 55810 | 5-BROMOTHIOPHENE-3-CARBOXYLIC ACID 97% | 100523-84-0 | 25G | $450 | 2026-04-30 | Buy |
| Chem-Impex | 30711 | 5-Bromothiophene-3-carboxylic acid ≥97%(HPLC) | 100523-84-0 | 1G | $72.31 | 2026-05-19 | Buy |
5-bromothiophene-3-carboxylic acid Chemical Properties,Uses,Production
Chemical Properties
White to off-white powder
Synthesis
88-13-1
100523-84-0
(d) Synthesis of 5-bromo-3-thiophenecarboxylic acid: a glacial acetic acid solution of bromine was prepared by dissolving 16 g of Br2 (0.1 mol) in 200 ml of glacial acetic acid. This solution was slowly added dropwise to 100 ml of glacial acetic acid solution containing 3-thiophenecarboxylic acid (12.8 g; 0.1 mol). The reaction mixture was stirred at room temperature for 20 minutes. Upon completion of the reaction, the mixture was poured into a vessel containing water and ice to quench the reaction and promote precipitation of the product. The resulting white precipitate was collected by filtration and washed with water to remove residual glacial acetic acid. Finally, the product was purified by recrystallization from water to give 5-bromo-3-thiophenecarboxylic acid in 70% yield.
References
[1] Tetrahedron Letters, 2013, vol. 54, # 11, p. 1460 - 1462
[2] Patent: US4767758, 1988, A
[3] Journal of Materials Chemistry C, 2018, vol. 6, # 14, p. 3731 - 3742
[4] Chemistry of Materials, 2010, vol. 22, # 19, p. 5617 - 5624
[5] Angewandte Chemie - International Edition, 2018, vol. 57, # 26, p. 7714 - 7718
5-bromothiophene-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8667 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
View Lastest Price from 5-bromothiophene-3-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-28 | 5-Bromo-3-thiophenecarboxylic acid
100523-84-0
|
US $17.00-261.00 / g | 5g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
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2026-03-30 | 5-bromothiophene-3-carboxylic acid
100523-84-0
|
US $0.00-0.00 / KG | 1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | |
![]() |
2026-03-20 | 5-bromothiophene-3-carboxylic acid
100523-84-0
|
US $9.90 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-

- 5-Bromo-3-thiophenecarboxylic acid
100523-84-0
- US $17.00-261.00 / g
- 0.98
- Shanghai UCHEM Inc.
-

- 5-bromothiophene-3-carboxylic acid
100523-84-0
- US $0.00-0.00 / KG
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-

- 5-bromothiophene-3-carboxylic acid
100523-84-0
- US $9.90 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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