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6,7-difluorochroman-4-one

CAS No.
1092349-93-3
Chemical Name:
6,7-difluorochroman-4-one
Synonyms
EOS-61820;6,7-difluorochroman-4-one;6,7-Difluro-2,3-dihydro-4H-1-benzopyranone;6,7-Difluoro-2,3-dihydro-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 6,7-difluoro-2,3-dihydro-
CBNumber:
CB01570713
Molecular Formula:
C9H6F2O2
Molecular Weight:
184.14
MDL Number:
MFCD11518477
MOL File:
1092349-93-3.mol
Last updated:2025-07-24 18:13:41

6,7-difluorochroman-4-one Properties

storage temp. Sealed in dry,Room Temperature
Appearance Light brown to brown Solid

SAFETY

Risk and Safety Statements

HS Code  2932990090

6,7-difluorochroman-4-one price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC907037 6,7-Difluorochroman-4-one 95% 1092349-93-3 250mg $62 2026-06-04 Buy
Apolloscientific PC907037 6,7-Difluorochroman-4-one 95% 1092349-93-3 1g $151 2026-06-04 Buy
aablocks AA008UE5 6,7-Difluorochroman-4-one 95% 1092349-93-3 250mg $91 2026-05-28 Buy
aablocks AA008UE5 6,7-Difluorochroman-4-one 95% 1092349-93-3 1g $202 2026-05-28 Buy
ACHEMBLOCK S87362 6,7-difluorochroman-4-one 95% 1092349-93-3 1G $120 2026-05-27 Buy
Product number Packaging Price Buy
PC907037 250mg $62 Buy
PC907037 1g $151 Buy
AA008UE5 250mg $91 Buy
AA008UE5 1g $202 Buy
S87362 1G $120 Buy

6,7-difluorochroman-4-one Chemical Properties, Uses, Production

Synthesis

3-(3,4-difluorophenoxy)propanoic acid

926256-60-2

6,7-difluorochroman-4-one

1092349-93-3

Step 2: 3-(3,4-difluorophenoxy)propionic acid (0.50 g, 2.5 mmol) was mixed with trifluoromethanesulfonic acid (5.0 mL, 56 mmol) and the reaction was stirred at room temperature for 18 hours. Upon completion of the reaction, the mixture was slowly poured into ice water (30 mL) to quench the reaction. The precipitated solid was collected by filtration to afford the target product 6,7-difluorobenzodihydropyran-4-one (370 mg, 81% yield) as a white solid. Mass spectrometric analysis showed m/z 185 [M + H]+ (electrospray ionization) with a retention time of 1.76 min (Analytical Method 1).

References

[1] Tetrahedron Letters, 2010, vol. 51, # 48, p. 6236 - 6239
[2] Patent: WO2016/142867, 2016, A1. Location in patent: Page/Page column 59; 60

6,7-difluorochroman-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 41)
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Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
LABTER PHARMATECH(BEIJING) CO.,LTD 010-56330744 18310155299 sales@labter.com.cn China 19999 55
BePharm Ltd 400-685-9117 market@bepharm.com China 15081 60
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 tcy@tcypharm.com China 8696 58
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Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shanghai Anmike Chemical Co. Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 9988 55
Taian Jiaye Biotechnology Co.Ltd 15318151873;13127280945 285424065@qq.com China 9961 55
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22344 58

6,7-difluorochroman-4-one Spectrum

6,7-difluorochroman-4-one 6,7-Difluoro-2,3-dihydro-4H-1-benzopyran-4-one EOS-61820 6,7-Difluro-2,3-dihydro-4H-1-benzopyranone 4H-1-Benzopyran-4-one, 6,7-difluoro-2,3-dihydro- 1092349-93-3