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N-P-TOSYLGLYCINE

N-P-TOSYLGLYCINE structure

CAS No.: 1080-44-0

Chemical Name:: N-P-TOSYLGLYCINE

Synonyms: Tos-Gly;TOS-GLY-OH;AURORA 963;N-TOS-Gly-OH;N-TOSYLGLYCINE;N-4-tosylglycine;N-P-TOSYLGLYCINE;N-p-Tosylglycine 97%;Tosylaminoacetic acid;OTAVA-BB BB0123400526

CBNumber:: CB0160643

Molecular Formula:: C9H11NO4S

Molecular Weight:: 229.25

MDL Number:: MFCD00045898

MOL File:: 1080-44-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:46

Product description	Number	Pack Size	Price
N-p-Tosylglycine 97%	403458	1g	$31
N-(p-Toluenesulfonyl)glycine >98.0%(HPLC)(T)	T2803	5g	$25
N-(p-Toluenesulfonyl)glycine >98.0%(HPLC)(T)	T2803	25g	$70
N-p-Tosylglycine >98%	T61808	25g	$28
N-p-Tosylglycine >98%	T61808	100g	$60
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N-P-TOSYLGLYCINE Properties

Melting point	147-149 °C (lit.)
Boiling point	430.0±55.0 °C(Predicted)
Density	1.369±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	3.41±0.10(Predicted)
form	Solid
color	White
Major Application	peptide synthesis
InChI	1S/C9H11NO4S/c1-7-2-4-8(5-3-7)15(13,14)10-6-9(11)12/h2-5,10H,6H2,1H3,(H,11,12)
InChIKey	VDKFCCZUCXYILI-UHFFFAOYSA-N
SMILES	Cc1ccc(cc1)S(=O)(=O)NCC(O)=O
CAS DataBase Reference	1080-44-0(CAS DataBase Reference)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

WGK Germany

HS Code

2935.90.9500

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

N-P-TOSYLGLYCINE price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	403458	N-p-Tosylglycine 97%	1080-44-0	1g	$31	2023-06-20	Buy
TCI Chemical	T2803	N-(p-Toluenesulfonyl)glycine >98.0%(HPLC)(T)	1080-44-0	5g	$25	2026-04-30	Buy
TCI Chemical	T2803	N-(p-Toluenesulfonyl)glycine >98.0%(HPLC)(T)	1080-44-0	25g	$70	2026-04-30	Buy
Synthonix	T61808	N-p-Tosylglycine >98%	1080-44-0	25g	$28	2026-05-06	Buy
Synthonix	T61808	N-p-Tosylglycine >98%	1080-44-0	100g	$60	2026-05-06	Buy

Product number	Packaging	Price	Buy
403458	1g	$31	Buy
T2803	5g	$25	Buy
T2803	25g	$70	Buy
T61808	25g	$28	Buy
T61808	100g	$60	Buy

N-P-TOSYLGLYCINE Chemical Properties,Uses,Production

Uses

N-Tosylglycine is a sulfonamide derivative used to synthesize metal complexes which potentially displays antibacterial activity.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

98-59-9

56-40-6

1080-44-0

Sodium carbonate (Na2CO3, 1.590 g, 15 mmol) was added to a solution of glycine (12.5 mmol) in water (15 mL) under continuous stirring until completely dissolved. The solution was cooled to -5°C and p-toluenesulfonyl chloride (15 mmol) was added in four batches over 1 hour. The reaction mixture was continued to be stirred at room temperature for about 4 h. The progress of the reaction was monitored using thin layer chromatography (TLC, unfolding agent was MeOH/DCM, 1:9). Upon completion of the reaction, the mixture was acidified with 20% aqueous hydrochloric acid to pH 2. The crystals were collected by diafiltration and washed with pH 2.2 buffer. The pure product 2-(4-methylphenylsulfonamido)acetic acid was dried in a desiccator. The yield was 99.34% (2.8410 g) and the melting point was 88.4-88.6°C. FTIR (KBr, cm-1 ): 3448 (O-H, COOH), 3277 (N-H), 2957 (C-H, aliphatic), 1730 (C=O), 1598, 1440 (C=C), 1354, 1321 (2S=O). 1185 (SO2-NH), 1111, 1094 (C-N, C-O).1H NMR (DMSO-d6) δ: 7.90-7.88 (t, J=6.3 Hz, 1H, NH), 7.65-7.63 (d, J=8.6 Hz, 2H, ArH), 7.34-7.33 (d, J=8.05 Hz, 2H, ArH ), 3.52-3.51 (d, J=5.7 Hz, 2H, CH2), 2.34 (s, 3H, CH3).13C NMR (DMSO-d6) δ: 170.7 (C=O), 143.1, 138.4, 130.0, 127.1 (aryl carbons), 44.3 (CH2), 21.5 (CH3).HRMS-ESI (m/z): 228.0412 ([M-H]-, calculated value: 228.0408).

References

[1] European Journal of Medicinal Chemistry, 2017, vol. 135, p. 349 - 369
[2] PLoS ONE, 2018, vol. 13, # 1,
[3] Journal of the American Chemical Society, 2018, vol. 140, # 17, p. 5834 - 5841
[4] Journal of Molecular Catalysis A: Chemical, 2011, vol. 351, p. 41 - 45
[5] Organic and Biomolecular Chemistry, 2018, vol. 16, # 31, p. 5618 - 5625

N-P-TOSYLGLYCINE Preparation Products And Raw materials

Raw materials

Tosyl chloride Glycine Sodium carbonate

Preparation Products

N-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-4-methylbenzenesulfonamide

N-P-TOSYLGLYCINE Suppliers

Global( 194)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29817	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
GL Biochem(Binhai) Ltd.	58
Dideu Industries Group Limited	58

View Lastest Price from N-P-TOSYLGLYCINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-08-12	N-P-TOSYLGLYCINE 1080-44-0	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-02	N-(p-Toluenesulfonyl)glycine 1080-44-0	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	N-P-TOSYLGLYCINE 1080-44-0	US $100.00 / KG	1KG	99%	Customized	Career Henan Chemical Co

N-P-TOSYLGLYCINE
1080-44-0
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

N-(p-Toluenesulfonyl)glycine
1080-44-0
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

N-P-TOSYLGLYCINE
1080-44-0
US $100.00 / KG
99%
Career Henan Chemical Co

N-P-TOSYLGLYCINE Spectrum

N-P-TOSYLGLYCINE(1080-44-0)MS N-P-TOSYLGLYCINE(1080-44-0)¹HNMR N-P-TOSYLGLYCINE(1080-44-0)IR1 N-P-TOSYLGLYCINE(1080-44-0)IR2

1080-44-0(N-P-TOSYLGLYCINE)Related Search:

TOS-PRO-OH N-(p-Tolylsulphonyl)-L-glutamic acid TOS-LYS(BOC)-OH N-(P-TOLUENESULFONYL)-L-PHENYLALANINE TOS-ARG-OH

N-P-TOSYLGLYCINE TOS-ARG-OME HCL TOS-GLU-OH TOS-GLY-OSU Tosyl-S-Benzyl-L-cysteine

TOS-MET-OH N-[P-TOLUENESULFONYL]-L-LYSINE METHYL ESTER HYDROCHLORIDE 2-([(4-METHYLPHENYL)SULFONYL]AMINO)-2-PHENYLACETIC ACID 4-METHYL-2-(TOLUENE-4-SULFONYLAMINO)-PENTANOIC ACID NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE

3-METHYL-2-(TOLUENE-4-SULFONYLAMINO)-BUTYRIC ACID 3-HYDROXY-2-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID 3-AMINO-2-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID

1of4

(4-METHYLPHENYLSULFONYLAMINO)ACETIC ACID N-4-tosylglycine N-TOS-Gly-OH N-(4-Toluenesulfonyl)-glycine N-(4-TOLUENESULFONYL)-GLYCINE N-P-TOSYLGLYCINE (Toluene-4-sulfonylamino)-acetic acid P-toluenesulfonate glycine Tosylaminoacetic acid 2-[(4-methylphenyl)sulfonylamino]acetic acid 2-[(4-methylphenyl)sulfonylamino]ethanoic acid 2-[(4-Methylbenzene)sulfonaMido]acetic acid N-Tosylglycine Tos-Gly-OH 2-(4-MethylphenylsulfonaMido)acetic acid Tos-Gly N-p-Tosylglycine 97% (p-Toluenesulfonamido)acetic acid Glycine, N-((4-methylphenyl)sulfonyl)- Glycine, N-[(4-methylphenyl)sulfonyl]- N-p-toluenesulfonyl-dl-glycine N-TOSYLGLYCINE (GLYCINE-13C2 N-((4-METHYLPHENYL)SULFONYL)GLYCINE P-TOLUENESULFONYLGLYCINE OTAVA-BB BB0123400526 N-TOSYLGLYCINE N-(P-TOLUENE SULFONYL) GLYCINE N-P-TOSYLGLYCINE TOS-GLY-OH AURORA 963 N-(p-Toluenesulfonyl)glycine N-P-TOSYLGLYCINE USP/EP/BP N-p-Tosylglycine 1080-44-0 CH3C6H4SO2NHCH2CO2H Amino Acid Derivatives Peptide Synthesis Specialty Synthesis Glycine [Gly, G]