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N-P-TOSYLGLYCINE

N-P-TOSYLGLYCINE Structure
N-P-TOSYLGLYCINE structure
CAS No.
1080-44-0
Chemical Name:
N-P-TOSYLGLYCINE
Synonyms
Tos-Gly;TOS-GLY-OH;AURORA 963;N-TOS-Gly-OH;N-TOSYLGLYCINE;N-4-tosylglycine;N-P-TOSYLGLYCINE;N-p-Tosylglycine 97%;Tosylaminoacetic acid;OTAVA-BB BB0123400526
CBNumber:
CB0160643
Molecular Formula:
C9H11NO4S
Molecular Weight:
229.25
MDL Number:
MFCD00045898
MOL File:
1080-44-0.mol
MSDS File:
SDS
Last updated:2025-08-08 17:45:00
Product description Number Pack Size Price
N-p-Tosylglycine 97% 403458 1g $31
N-(p-Toluenesulfonyl)glycine >98.0%(HPLC)(T) T2803 5g $31
N-(p-Toluenesulfonyl)glycine >98.0%(HPLC)(T) T2803 25g $88
N-Tosylglycine T631720 5g $95
(4-Methylphenylsulfonylamino)aceticacid,≥98%(HPLC) ≥98%(HPLC) 16453 5G $23.3
More product size
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N-P-TOSYLGLYCINE Properties

Melting point 147-149 °C (lit.)
Boiling point 430.0±55.0 °C(Predicted)
Density 1.369±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.41±0.10(Predicted)
color White
CAS DataBase Reference 1080-44-0(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HS Code  2935.90.9500
NFPA 704
1
2 0

N-P-TOSYLGLYCINE price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 403458 N-p-Tosylglycine 97% 1080-44-0 1g $31 2023-06-20 Buy
TCI Chemical T2803 N-(p-Toluenesulfonyl)glycine >98.0%(HPLC)(T) 1080-44-0 5g $31 2025-07-31 Buy
TCI Chemical T2803 N-(p-Toluenesulfonyl)glycine >98.0%(HPLC)(T) 1080-44-0 25g $88 2025-07-31 Buy
TRC T631720 N-Tosylglycine 1080-44-0 5g $95 2021-12-16 Buy
Chem-Impex 16453 (4-Methylphenylsulfonylamino)aceticacid,≥98%(HPLC) ≥98%(HPLC) 1080-44-0 5G $23.3 2021-12-16 Buy
Product number Packaging Price Buy
403458 1g $31 Buy
T2803 5g $31 Buy
T2803 25g $88 Buy
T631720 5g $95 Buy
16453 5G $23.3 Buy

N-P-TOSYLGLYCINE Chemical Properties,Uses,Production

Uses

N-Tosylglycine is a sulfonamide derivative used to synthesize metal complexes which potentially displays antibacterial activity.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

Tosyl chloride

98-59-9

Glycine

56-40-6

N-P-TOSYLGLYCINE

1080-44-0

Sodium carbonate (Na2CO3, 1.590 g, 15 mmol) was added to a solution of glycine (12.5 mmol) in water (15 mL) under continuous stirring until completely dissolved. The solution was cooled to -5°C and p-toluenesulfonyl chloride (15 mmol) was added in four batches over 1 hour. The reaction mixture was continued to be stirred at room temperature for about 4 h. The progress of the reaction was monitored using thin layer chromatography (TLC, unfolding agent was MeOH/DCM, 1:9). Upon completion of the reaction, the mixture was acidified with 20% aqueous hydrochloric acid to pH 2. The crystals were collected by diafiltration and washed with pH 2.2 buffer. The pure product 2-(4-methylphenylsulfonamido)acetic acid was dried in a desiccator. The yield was 99.34% (2.8410 g) and the melting point was 88.4-88.6°C. FTIR (KBr, cm-1 ): 3448 (O-H, COOH), 3277 (N-H), 2957 (C-H, aliphatic), 1730 (C=O), 1598, 1440 (C=C), 1354, 1321 (2S=O). 1185 (SO2-NH), 1111, 1094 (C-N, C-O).1H NMR (DMSO-d6) δ: 7.90-7.88 (t, J=6.3 Hz, 1H, NH), 7.65-7.63 (d, J=8.6 Hz, 2H, ArH), 7.34-7.33 (d, J=8.05 Hz, 2H, ArH ), 3.52-3.51 (d, J=5.7 Hz, 2H, CH2), 2.34 (s, 3H, CH3).13C NMR (DMSO-d6) δ: 170.7 (C=O), 143.1, 138.4, 130.0, 127.1 (aryl carbons), 44.3 (CH2), 21.5 (CH3).HRMS-ESI (m/z): 228.0412 ([M-H]-, calculated value: 228.0408).

References

[1] European Journal of Medicinal Chemistry, 2017, vol. 135, p. 349 - 369
[2] PLoS ONE, 2018, vol. 13, # 1,
[3] Journal of the American Chemical Society, 2018, vol. 140, # 17, p. 5834 - 5841
[4] Journal of Molecular Catalysis A: Chemical, 2011, vol. 351, p. 41 - 45
[5] Organic and Biomolecular Chemistry, 2018, vol. 16, # 31, p. 5618 - 5625

N-P-TOSYLGLYCINE Preparation Products And Raw materials

Raw materials

Tosyl chloride Glycine Sodium carbonate

Preparation Products

N-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-4-methylbenzenesulfonamide

N-P-TOSYLGLYCINE Suppliers

Global( 198)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29734 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Hubei xin bonus chemical co. LTD 		58
BOC Sciences 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
SIMAGCHEM CORP 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
GL Biochem(Binhai) Ltd. 		58

View Lastest Price from N-P-TOSYLGLYCINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-P-TOSYLGLYCINE pictures 2021-08-12 N-P-TOSYLGLYCINE
1080-44-0
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
N-(p-Toluenesulfonyl)glycine pictures 2021-07-02 N-(p-Toluenesulfonyl)glycine
1080-44-0
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
N-P-TOSYLGLYCINE pictures 2019-07-06 N-P-TOSYLGLYCINE
1080-44-0
 US $100.00 / KG 1KG 99% Customized Career Henan Chemical Co
  • N-P-TOSYLGLYCINE pictures
  • N-P-TOSYLGLYCINE
    1080-44-0
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

N-P-TOSYLGLYCINE Spectrum

N-P-TOSYLGLYCINE(1080-44-0)MSN-P-TOSYLGLYCINE(1080-44-0)1HNMRN-P-TOSYLGLYCINE(1080-44-0)IR1N-P-TOSYLGLYCINE(1080-44-0)IR2

1080-44-0(N-P-TOSYLGLYCINE)Related Search:

TOS-PRO-OH N-(p-Tolylsulphonyl)-L-glutamic acid TOS-LYS(BOC)-OH N-(P-TOLUENESULFONYL)-L-PHENYLALANINE TOS-ARG-OH
N-P-TOSYLGLYCINE TOS-ARG-OME HCL TOS-GLU-OH TOS-GLY-OSU Tosyl-S-Benzyl-L-cysteine
TOS-MET-OH N-[P-TOLUENESULFONYL]-L-LYSINE METHYL ESTER HYDROCHLORIDE 2-([(4-METHYLPHENYL)SULFONYL]AMINO)-2-PHENYLACETIC ACID 4-METHYL-2-(TOLUENE-4-SULFONYLAMINO)-PENTANOIC ACID NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE
3-METHYL-2-(TOLUENE-4-SULFONYLAMINO)-BUTYRIC ACID 3-HYDROXY-2-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID 3-AMINO-2-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID

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(4-METHYLPHENYLSULFONYLAMINO)ACETIC ACID N-4-tosylglycine N-TOS-Gly-OH N-(4-Toluenesulfonyl)-glycine N-(4-TOLUENESULFONYL)-GLYCINE N-P-TOSYLGLYCINE (Toluene-4-sulfonylamino)-acetic acid P-toluenesulfonate glycine Tosylaminoacetic acid 2-[(4-methylphenyl)sulfonylamino]acetic acid 2-[(4-methylphenyl)sulfonylamino]ethanoic acid 2-[(4-Methylbenzene)sulfonaMido]acetic acid N-Tosylglycine Tos-Gly-OH 2-(4-MethylphenylsulfonaMido)acetic acid Tos-Gly N-p-Tosylglycine 97% (p-Toluenesulfonamido)acetic acid Glycine, N-((4-methylphenyl)sulfonyl)- Glycine, N-[(4-methylphenyl)sulfonyl]- N-p-toluenesulfonyl-dl-glycine N-TOSYLGLYCINE (GLYCINE-13C2 N-((4-METHYLPHENYL)SULFONYL)GLYCINE P-TOLUENESULFONYLGLYCINE OTAVA-BB BB0123400526 N-TOSYLGLYCINE N-(P-TOLUENE SULFONYL) GLYCINE N-P-TOSYLGLYCINE TOS-GLY-OH AURORA 963 N-(p-Toluenesulfonyl)glycine N-P-TOSYLGLYCINE USP/EP/BP N-p-Tosylglycine 1080-44-0 CH3C6H4SO2NHCH2CO2H Amino Acid Derivatives Peptide Synthesis Specialty Synthesis Glycine [Gly, G]