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CYCLO(-GLY-PRO)

CYCLO(-GLY-PRO) structure

CAS No.: 3705-27-9

Chemical Name:: CYCLO(-GLY-PRO)

Synonyms: y-Pro);cyclo-GP;cyclo(pro-gly);CYCLO(-GLY-PRO);Cyclic (Pro-Gly);Cyclo(Gly-L-Pro);Cycloglycylproline;Cyclo(L-prolylglycyl);Cycloglycyl-L-proline;Cyclo-L-prolylglycine

CBNumber:: CB0173177

Molecular Formula:: C7H10N2O2

Molecular Weight:: 154.17

MDL Number:: MFCD00055967

MOL File:: 3705-27-9.mol

Last updated:2025-04-29 15:35:11

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CYCLO(-GLY-PRO) Properties

Melting point	220-223℃
Boiling point	447.9±34.0 °C(Predicted)
Density	1.32
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMSO: >10mg/mL
pka	13.21±0.20(Predicted)
form	powder
InChIKey	OWOHLURDBZHNGG-YFKPBYRVSA-N
UNSPSC Code	12352200
NACRES	NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H227
Precautionary statements	P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235
WGK Germany	3

CYCLO(-GLY-PRO) price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	C2374	Cyclo-Gly-Pro ≥98% (GC/HPLC)	3705-27-9	10mg	$101	2024-03-01	Buy
TRC	C987455	Cyclo(-Gly-Pro)	3705-27-9	25mg	$195	2021-12-16	Buy
Biosynth Carbosynth	FC49430	Cyclo(-Gly-Pro)	3705-27-9	2g	$500	2021-12-16	Buy
Medical Isotopes, Inc.	36197	Cyclo(-Gly-Pro)	3705-27-9	1g	$500	2021-12-16	Buy
SynQuest Laboratories	4H48-1-BT	(S)-Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione	3705-27-9	5G	$550	2021-12-16	Buy

Product number	Packaging	Price	Buy
C2374	10mg	$101	Buy
C987455	25mg	$195	Buy
FC49430	2g	$500	Buy
36197	1g	$500	Buy
4H48-1-BT	5G	$550	Buy

CYCLO(-GLY-PRO) Chemical Properties,Uses,Production

Chemical Properties

White crystal

Uses

Cyclo(-?Gly-?Pro) and its derivatives can be used as Cyclic Dipeptide Chitinase Inhibitors. It is also used to synthesize 5-HT1A receptor agonists.

Biological Activity

Cyclo-Gly-Pro is a neuro-protective compound, an endogenous diketopiperazine, which enhances memory. In the animal model of PD, the compound improved functional recovery when administered after the onset of dyskinesia. It appears th at the compound recovery function may result from non-proliferative neurogenesis th at results from the inhibition of apoptosis of stem cells and/or the promotion of neuronal-orientated proliferation in the SVZ (subventricular zone).

CYCLO(-GLY-PRO) Preparation Products And Raw materials

Raw materials

Preparation Products

CYCLO(-GLY-PRO) Suppliers

Global( 124)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3944	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Chengdu Feibo Pharm Technology Co., Ltd	+86 028-84641798 15982321820	abby@arkpharm.com	China	10922	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
RongNa Biotechnology Co.,Ltd	+86-86-13583358881 +8618560316533	Brad@rongnabiotech.com	China	3073	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9642	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Chengdu Feibo Pharm Technology Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
ANHUI WITOP BIOTECH CO., LTD	58
RongNa Biotechnology Co.,Ltd	58
Finetech Industry Limited	58
Hefei Hirisun Pharmatech Co., Ltd	58

View Lastest Price from CYCLO(-GLY-PRO) manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-05-14	CYCLO(-GLY-PRO) 3705-27-9			0.99		RongNa Biotechnology Co.,Ltd
2024-10-24	Cyclo(Gly-L-Pro) 3705-27-9	US $50.00 / mg			10g	TargetMol Chemicals Inc.
2024-07-20	CYCLO(-GLY-PRO) 3705-27-9	US $1.00 / Kg	1Kg	98%	20T	Shaanxi Dideu Medichem Co. Ltd

CYCLO(-GLY-PRO)
3705-27-9
0.99
RongNa Biotechnology Co.,Ltd

Cyclo(Gly-L-Pro)
3705-27-9
US $50.00 / mg
TargetMol Chemicals Inc.

CYCLO(-GLY-PRO)
3705-27-9
US $1.00 / Kg
98%
Shaanxi Dideu Medichem Co. Ltd

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CYCLO(-GLY-PRO) cyclo(pro-gly) Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-, (8aS)- (9CI) (8AS)-HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Cyclic (Pro-Gly) (S)-3,6-Dioxohexahydropyrrolo[1,2-a]pyrazine cyclo-GP (8aS)-octahydropyrrolo[1,2-a]piperazine-1,4-dione (S)-Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(glycyl-L-prolyl) Cyclo(Gly-L-Pro) Cyclo(L-prolylglycyl) Cycloglycyl-L-proline Cycloglycylproline Cyclo-L-prolylglycine Glycyl-L-proline lactam Pyrrolo[1,2-a]pyrazine-1,4-dione,hexahydro-, (8aS)- (8aS)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(-Gly-Pro)≥ 99% (HPLC) y-Pro) Cyclo-Gly-Pro >=98% (GC/HPLC) 3705-27-9 PYRROLE PIPERIDINE