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6-Fluoro-1-indanone

6-Fluoro-1-indanone Structure
6-Fluoro-1-indanone structure
CAS No.
1481-32-9
Chemical Name:
6-Fluoro-1-indanone
Synonyms
6-Fluoro-2,3-dihydro-1H-inden-1-one;6-FLUOROINDANONE;6-fluro-indanone;6-Fluorindan-1-on;6-Fluoro-indan-1-on;6-FLUORO-1-INDANONE;6-Fluoro-1-indenone;6-FLURORO-1-INDANONE;6-FLUORO-INDAN-1-ONE;6-FLUORORO-1-INDANONE
CBNumber:
CB0196811
Molecular Formula:
C9H7FO
Molecular Weight:
150.15
MDL Number:
MFCD01318147
MOL File:
1481-32-9.mol
Last updated:2026-01-13 11:12:08
Product description Number Pack Size Price
6-Fluoro-1-indanone 96% 663123 5g $559
6-Fluoro-1-indanone 96% 663123 1g $98
6-Fluoro-1-indanone >98.0%(GC) F0668 1g $84
6-Fluoro-1-indanone >98.0%(GC) F0668 5g $249
6-Fluoro-2,3-dihydro-1H-inden-1-one F595423 100mg $45
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6-Fluoro-1-indanone Properties

Melting point 56-60 °C
Boiling point 60 °C/0.07kPa
Density 1.259±0.06 g/cm3(Predicted)
Flash point 60°C/0.5mm
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form Crystalline Powder
color Off-white to pale brown
BRN 1448695
InChI InChI=1S/C9H7FO/c10-7-3-1-6-2-4-9(11)8(6)5-7/h1,3,5H,2,4H2
InChIKey LVUUCFIQQHEFEJ-UHFFFAOYSA-N
SMILES C1(=O)C2=C(C=CC(F)=C2)CC1
CAS DataBase Reference 1481-32-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36-37
WGK Germany  2
HazardClass  IRRITANT
HS Code  29147000
Storage Class 13 - Non Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
NFPA 704
1
2 0

6-Fluoro-1-indanone price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 663123 6-Fluoro-1-indanone 96% 1481-32-9 5g $559 2023-06-20 Buy
Sigma-Aldrich 663123 6-Fluoro-1-indanone 96% 1481-32-9 1g $98 2022-05-15 Buy
TCI Chemical F0668 6-Fluoro-1-indanone >98.0%(GC) 1481-32-9 1g $84 2025-07-31 Buy
TCI Chemical F0668 6-Fluoro-1-indanone >98.0%(GC) 1481-32-9 5g $249 2025-07-31 Buy
TRC F595423 6-Fluoro-2,3-dihydro-1H-inden-1-one 1481-32-9 100mg $45 2021-12-16 Buy
Product number Packaging Price Buy
663123 5g $559 Buy
663123 1g $98 Buy
F0668 1g $84 Buy
F0668 5g $249 Buy
F595423 100mg $45 Buy

6-Fluoro-1-indanone Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

6-Fluoro-1-indanone is an intermediate compound that can be used as an organic synthesis raw material for the preparation of pharmaceutical and chemical products. It is also an excellent reaction reagent that can undergo various chemical reactions, including oxidation, reduction and substitution.

Synthesis

Benzenepropanoyl chloride, 4-fluoro-

772-70-3

6-Fluoro-1-indanone

1481-32-9

The general procedure for the synthesis of 6-fluoro-1-indanone from 4-fluoro-benzenepropanoyl chloride was as follows: aluminum trichloride (AlCl3, 27.8 g, 208 mmol) was suspended in 200 mL of 1,2-dichloroethane. The mixture was cooled to 0-5 °C under nitrogen protection and a solution of 4-fluoro-phenylpropionyl chloride (27.75 g, 148.8 mmol) dissolved in 140 mL of 1,2-dichloroethane was added slowly and dropwise over a period of 1 hour. After removal of the cooling bath, stirring was continued for 30 minutes, followed by 2 hours of reaction at 70°C. Upon completion of the reaction, the mixture was cooled to room temperature and poured into a mixture of ice and 330 mL of concentrated hydrochloric acid (36-38%). The aqueous layer was extracted with dichloromethane (CH2Cl2) and the combined organic layers were washed sequentially with water (2×), 5% sodium bicarbonate (NaHCO3) solution and saturated saline. The organic layer was dried over anhydrous magnesium sulfate (MgSO4), filtered to remove the desiccant, and the solvent was evaporated under reduced pressure to give 19.02 g of 6-fluoro-1-indanone in 85% yield.

References

[1] Patent: US2006/122189, 2006, A1. Location in patent: Page/Page column 27
[2] Bulletin de la Societe Chimique de France, 1973, p. 3092 - 3095
[3] Journal of Medicinal Chemistry, 2003, vol. 46, # 3, p. 399 - 408
[4] European Journal of Organic Chemistry, 2007, # 18, p. 2987 - 2994
[5] Patent: US5872118, 1999, A

6-Fluoro-1-indanone synthesis

772-70-3
1481-32-9
Synthesis of 6-Fluoro-1-indanone from Benzenepropanoyl chloride, 4-fluoro-

6-Fluoro-1-indanone Preparation Products And Raw materials

Raw materials

Benzenepropanoyl chloride, 4-fluoro- 2-Bromo-5-fluorobenzaldehyde 3-CHLORO-4'-FLUOROPROPIOPHENONE 5-Fluoro-2-vinyl-benzaldehyde Methyl 3-(4-fluorophenyl)propanoate
4-Fluorostyrene 4-Fluorobenzaldehyde 3-(4-FLUOROPHENYL)PROPIONIC ACID Aluminum chloride 1,2-Dichloroethane

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Preparation Products

2,3-DIHYDRO-2,2-DIMETHYL-6-FLUORO-1H-INDEN-1-ONE 2-BROMO-2,3-DIHYDRO-6-FLUORO-1H-INDEN-1-ONE

6-Fluoro-1-indanone Suppliers

Global( 259)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8752 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13798 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29830 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10405 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from 6-Fluoro-1-indanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Fluoro-1-indanone pictures 2026-03-06 6-Fluoro-1-indanone
1481-32-9
 US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
6-Fluoro-1-indanone pictures 2025-12-01 6-Fluoro-1-indanone
1481-32-9
 US $0.00-0.00 / KG 1KG 98 10000KGS Shaanxi Dideu New Materials Co. Ltd
6-Fluoro-1-indanone pictures 2025-04-04 6-Fluoro-1-indanone
1481-32-9
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

6-Fluoro-1-indanone Spectrum

6-Fluoro-1-indanone(1481-32-9)1HNMR

1481-32-9(6-Fluoro-1-indanone)Related Search:

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6-fluro-indanone 6-FLURORO-1-INDANONE 6-FLUOROINDANONE 6-Fluoro-1-indenone 6-Fluoro-2,3-dihydro-1H-inden-1-one 6-Fluoro-indan-1-on 1H-Inden-1-one, 6-fluoro-2,3-dihydro- 6-FLUORO-2,3-DIHYDROINDEN-1-ONE 6-FLUORO-1-INDANONE 6-FLUORO-INDAN-1-ONE 6-FLUORORO-1-INDANONE JR-6920, 6-Fluoro-2,3-dihydroinden-1-one, 97% 6-Fluoro-1-indanone> 6-Fluorindan-1-on tert-butyl 3-(1-amino-2,2,2-trifluoroethyl)-5-bromobenzoate 1481-32-9 C9H7FO Ketones Organic Building Blocks C9 Carbonyl Compounds Building Blocks Indane/Indanone and Derivatives pharmacetical Indanone & Indene