DEATH RECEPTOR 5
- CAS No.
- Chemical Name:
- DEATH RECEPTOR 5
- Synonyms
- DR5;KILER;KILLER;PRO186;TRICKB;UNQ160;ZTNFR9;TRICK2A;TRICK2B;HUMAN DR5
- CBNumber:
- CB0198981
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03792341
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| sTRAIL Receptor-2 (DR5) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | SRP3165 | 50 μg | $312 |
| TNFRSF10B PurifiedbyProteinGaffinitychromatography. | 579559 | 50ug | $509 |
| TNFRSF10B PurifiedbyProteinGaffinitychromatography. | 579559 | 100ug | $708 |
| TNFRSF10B Purified | 553284 | 100ug | $722 |
| TNFRSF10B Purifiedbyimmunoaffinitychromatography. | 529158 | 100ul | $736 |
| storage temp. | -20°C |
|---|---|
| form | lyophilized |
| color | white |
| biological source | human |
| NCI Dictionary of Cancer Terms | death receptor 5; DR5 |
| UNSPSC Code | 51111800 |
| NACRES | NA.32 |
DEATH RECEPTOR 5 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3165 | sTRAIL Receptor-2 (DR5) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 50 μg | $312 | 2025-07-31 | Buy | |
| Usbiological | 579559 | TNFRSF10B PurifiedbyProteinGaffinitychromatography. | 50ug | $509 | 2026-06-03 | Buy | |
| Usbiological | 579559 | TNFRSF10B PurifiedbyProteinGaffinitychromatography. | 100ug | $708 | 2026-06-03 | Buy | |
| Usbiological | 553284 | TNFRSF10B Purified | 100ug | $722 | 2026-06-03 | Buy | |
| Usbiological | 529158 | TNFRSF10B Purifiedbyimmunoaffinitychromatography. | 100ul | $736 | 2026-06-03 | Buy |
DEATH RECEPTOR 5 Chemical Properties,Uses,Production
Uses
DR5 (death receptor 5) or TNFRSF10B (tumor necrosis factor receptor superfamily member 10b) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is a tumor suppressor gene localized to human chromosome 8p and is composed of 10 coding exons. The encoded protein is an integral plasma membrane protein.
Recombinant human sTNFRII is an 18.9 kDa protein (174 amino acid residues) comprising the cysteine rich ligand binding portion of the extracellular domain of the TNFRII protein.
Biological Activity
It initiates the formation of death-inducing signal complex (DISC) by recruiting fas-associated death domain (FADD) and caspases to its cytoplasmic death domain (DD). In human lung cancer cells, parthenolide (PTL) induces extrinsic apoptosis by up-regulating TNFRSF10B. Deregulation of this gene results in metastasis, invasion and migration of tumor cells. Mutation leads to loss of p arm in this gene which is frequently the case in head and neck tumors. In a breast cancer xenograft mouse model, DR5 facilitates skeletal metastasis. In prostate carcinoma (PCa) and prostatic intraepithelial neoplasia (PIN), the expression of DR5 is lower in higher grade tumors.
DEATH RECEPTOR 5 Preparation Products And Raw materials
Raw materials
Preparation Products
DEATH RECEPTOR 5 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10308 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| CUSABIO TECHNOLOGY LLC | 027-87196173 | cusabio@163.com | China | 6066 | 58 |
| ZSGB-BIO | 02-400-810-9781 400810978 | sales@zsbio.com | China | 2887 | 58 |
| Kamiya Biomedical Company | 1-+1 206-575-8068 1206-575-8068 | ordering@k-assay.com | China | 928 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Wanlei Life Sciences (Shenyang) Co Ltd | 400-6020407 | sales@wanleibio.com | China | 1216 | 58 |
| Beijing Biosynthesis Biotechnology Co Ltd | 400-9019800 | sales@bioss.com.cn | China | 6102 | 58 |
| Biosharp | 400-600-4213 | info@labgic.com | China | 6191 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8132 | 58 |
