trans-Clomiphene Citrate
- CAS No.
- 7599-79-3
- Chemical Name:
- trans-Clomiphene Citrate
- Synonyms
- Enclomiphene citrate;Enclomifene citrate;Androxal;Enclomid;Unii-J303A6U9Y6;Clomiphene B citrate;(E)-Clomiphene citrate;tans-clomifene citrate;trans-clomifene citrate;trans-Clomiphene citrate
- CBNumber:
- CB02079569
- Molecular Formula:
- C32H36ClNO8
- Molecular Weight:
- 598.09
- MDL Number:
- MFCD00058322
- MOL File:
- 7599-79-3.mol
| Melting point | 143-145°C |
|---|---|
| storage temp. | Amber Vial, -20°C Freezer |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicated) |
| form | Solid |
| color | White to Off-White |
| Stability | Light Sensitive |
| InChIKey | PYTMYKVIJXPNBD-BTKVJIOYSA-N |
| EWG's Food Scores | 1 |
| FDA UNII | J303A6U9Y6 |
| NCI Drug Dictionary | enclomiphene citrate |
trans-Clomiphene Citrate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C587045 | trans-ClomipheneCitrate | 7599-79-3 | 10mg | $125 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0018264 | TRANS-EMCLOMIPHENE CITRATE 95.00% | 7599-79-3 | 1G | $351.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0018264 | TRANS-EMCLOMIPHENE CITRATE 95.00% | 7599-79-3 | 10G | $1166.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0018264 | TRANS-EMCLOMIPHENE CITRATE 95.00% | 7599-79-3 | 100G | $3326.4 | 2021-12-16 | Buy |
| DC Chemicals | DC8177 | Enclomiphenecitrate >98% | 7599-79-3 | 100mg | $450 | 2021-12-16 | Buy |
trans-Clomiphene Citrate Chemical Properties,Uses,Production
Uses
trans-Clomiphene Citrate, stereoisomer of Clomiphene Citrate (C587025), a synthetic estrogen agonist-antagonist. Gonad-stimulating principle.
Toxicology
The effects of the cis and trans isomers of clomiphene citrate on the uterine hexokinase activity of immature ovariectomized rats were studied in long- and short-term experiments. At a dose level of 600 μg/kg, both trans-Clomiphene Citrate and cis-Clomiphene Citrate caused a similar increase in total uterine hexokinase activity observable in 18 hr. When enzyme activity was expressed per g of the uterus (specific activity), significant increases were noted 18 hr after a single injection of trans clomiphene or after 4 daily injections of either isomer. Treatment of these animals with 170-estradiol (5 μg/kg) caused an elevation of both the specific and total hexokinase activities within 18 hr[1].
in vivo
Enclomiphene citrate (subcutaneous injection, 0.25 and 0.5 mg/animal, daily) inhibits spermatogenesis and decreases serum luteinizing hormone (LH) and testosterone levels in intact or castrated rats[5].
Enclomiphene citrate (oral adminstration, 0.03-3 mg/kg, daily for 90 days) reductes body weight to sham levels, and reduced serum cholesterol[6].
| Animal Model: | 21 days-old Charles River male rats[5] |
| Dosage: | 0.25 and 0.5 mg/animal, daily for 24 days. |
| Administration: | Subcutaneous injection |
| Result: | Decreased LH and testosterone levels in the serum. |
| Animal Model: | OVX (ovariectomy) rat model[6] |
| Dosage: | 0.03, 1, and 3 mg/kg, daily for 90 days. |
| Administration: | Oral adminstration |
| Result: | Reducted body weight to sham levels, and reduced serum cholesterol. Showed dose-dependent effects on the proximal tibia with BMD and BMC approaching posttreatment Sham levels. |
References
[1] D L DiPietro, D A Goss, F J Sanders. “Effect of cis and trans isomers of clomiphene citrate on uterine hexokinase activity.” Endocrinology 84 6 (1969): 1404–8.
trans-Clomiphene Citrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7934 | 58 |
| Wuhan Nutra Biotechnology Co.,Ltd | +8617786394783 | nutrabiotech@outlook.com | China | 300 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Hebei Lingding Biotechnology Co., Ltd. | +86-18134017493 +86-18134017493 | sunflowerfranklin20@gmail.com | China | 108 | 58 |
| Hubei KDG Web Science&Technology Co., Ltd | 18672314556 +8618672314556 | sales@kdg-tech.com | China | 933 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3883 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12788 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7890 | 58 |
| HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 | sales2@runyanpharma.com | China | 302 | 58 |
| Jinan Million Pharmaceutical Co., Ltd | 0531-68659554 +8613031714605 | info@millionpharm.com | China | 291 | 58 |
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View Lastest Price from trans-Clomiphene Citrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-14 | trans-Clomiphene Citrate
7599-79-3
|
US $1.00-1.00 / kg | 0.0001kg | 99% | 200KG | Jinan Million Pharmaceutical Co., Ltd | |
 |
2025-05-14 | Trans-clomifene citrate
7599-79-3
|
US $8.00 / kg | 1kg | 0.99 | 100000 | Hebei Fengjia New Material Co., Ltd | |
 |
2025-05-14 | trans-Clomiphene Citrate
7599-79-3
|
US $0.00-0.00 / G | 1G | 99% | 1 ton/year | Forest chemical technology |
-
- trans-Clomiphene Citrate
7599-79-3
- US $1.00-1.00 / kg
- 99%
- Jinan Million Pharmaceutical Co., Ltd
-
- Trans-clomifene citrate
7599-79-3
- US $8.00 / kg
- 0.99
- Hebei Fengjia New Material Co., Ltd
-
- trans-Clomiphene Citrate
7599-79-3
- US $0.00-0.00 / G
- 99%
- Forest chemical technology
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