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D-CAMPHOR

D-CAMPHOR Structure
D-CAMPHOR structure
CAS No.
464-49-3
Chemical Name:
D-CAMPHOR
Synonyms
Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)-;(1R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one;d-2-Bornanone;d-camphre;FEMA 2230;D-2-CAMPHANONE;CAMPHOR POWDER DAB 8;7,7-trimethyl-(1r)-bicyclo(2.2.1)heptan-2-on;(1R)-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-ONE;D-CAMPHOR
CBNumber:
CB0233316
Molecular Formula:
C10H16O
Molecular Weight:
152.23
MDL Number:
MFCD00064149
MOL File:
464-49-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-20 23:19:27
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D-CAMPHOR Properties

Melting point 178-182 °C (lit.)
Boiling point 204 °C
alpha D25 +41 to +43° (c = 10 in U.S.P. alcohol) according to U.S.P. specif
Density 0,99 g/cm3
vapor density 5.24 (vs air)
vapor pressure 4 mm Hg ( 70 °C)
refractive index 44.5 ° (C=20, EtOH)
FEMA 2230 | D-CAMPHOR
FLAVIS Number 07.215 | d-Camphor
Flash point 148 °F
storage temp. 2-8°C
solubility Slightly soluble in water, very soluble in alcohol and in light petroleum, freely soluble in fatty oils, very slightly soluble in glycerol.
form Crystals
color White
Odor at 10.00 % in dipropylene glycol. camphor minty phenolic herbal woody
Odor Type camphoreous
biological source synthetic
optical activity [α]25/D +44°, c = 10 in ethanol
explosive limit 3.5%
Water Solubility Soluble in water (0.1 g/L at 20°C).
Merck 14,1732
JECFA Number 1395
BRN 2042745
Stability Stable. Incompatible with strong reducing agents, strong oxidizing agents, chlorinated solvents. Protect from direct sunlight.
Cosmetics Ingredients Functions DENATURANT
FRAGRANCE
PLASTICISER
InChI 1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1
InChIKey DSSYKIVIOFKYAU-XCBNKYQSSA-N
SMILES C[C@@]1(CC2)C(C)(C)[C@H]2CC1=O
LogP 2.3 at 20℃
Substances Added to Food (formerly EAFUS) D-CAMPHOR
FDA 21 CFR 172.515
CAS DataBase Reference 464-49-3(CAS DataBase Reference)
FDA UNII N20HL7Q941
EPA Substance Registry System D-Camphor (464-49-3)
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Corrosion (GHS05)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS02,GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H228-H315-H318-H332-H371
Precautionary statements  P210-P280-P302+P352-P304+P340+P312-P305+P351+P338-P308+P311
target organs Lungs
PPE Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  F,Xn,Xi
Risk Statements  11-22-36/37/38-20/21/22-36
Safety Statements  16-26-36-37/39
RIDADR  UN 2717
WGK Germany  1
RTECS  EX1260000
Autoignition Temperature 870 °F
TSCA  TSCA listed
HazardClass  4.1
PackingGroup  III
HS Code  29142910
Storage Class 4.1B - Flammable solid hazardous materials
Hazard Classifications Acute Tox. 4 Inhalation
Eye Dam. 1
Flam. Sol. 2
Skin Irrit. 2
STOT SE 2 Inhalation
REACH Registrations Active
Limited Quantities 5.0 Kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
2 0

D-CAMPHOR price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W223018 D-Camphor ≥97%, FG 464-49-3 1 each $58 2026-04-30 Buy
Sigma-Aldrich W223018 D-Camphor ≥97%, FG 464-49-3 1kg $79.9 2026-04-30 Buy
Sigma-Aldrich W223018 D-Camphor ≥97%, FG 464-49-3 10Kg $545 2026-04-30 Buy
Sigma-Aldrich 50843 D-Camphor analytical standard 464-49-3 100mg $109 2026-04-30 Buy
Sigma-Aldrich 1087508 Camphor United States Pharmacopeia (USP) Reference Standard 464-49-3 1g $441 2026-04-30 Buy
Product number Packaging Price Buy
W223018 1 each $58 Buy
W223018 1kg $79.9 Buy
W223018 10Kg $545 Buy
50843 100mg $109 Buy
1087508 1g $441 Buy

D-CAMPHOR Chemical Properties, Uses, Production

Description

(1R)-(+)-Camphor is a terpene that has been found in C. sativa, C. indica, and C. sativa/C. indica hybrid strains as well as the essential oils from a variety of herbs including rosemary, lavender, and sage and has diverse biological activities. It inhibits norepinephrine secretion and cytosolic calcium and sodium increases induced by the nicotinic acetylcholine receptor (nAChR) agonist 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) in chromaffin cells (IC50s = 70, 88, and 19 μM, respectively). (1R)-(+)-Camphor (65-260 μM) induces proliferation of and increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in human primary dermal fibroblasts. In vivo, (1R)-(+)-camphor increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in skin in UV-exposed mice when administered at doses of 26 and 55 mM in drinking water post UV-exposure. It reduces cough frequency in citric acid-challenged guinea pigs. (1R)-(+)-Camphor is insecticidal, reducing digging activity and inducing mortality of fire ant workers. It has also been used as a building block in the synthesis of cannabinergic ligands.

Chemical Properties

d-Camphor has a warm, minty, almost ethereal diffusive aroma. For other details of description, see Camphor Tree.

Chemical Properties

white crystals

Occurrence

Frequently occurring in nature as the d- or l-form; the optically inactive form is seldom encountered. The d-form has been reported found in Cinnamomum camphora Ness. (Laurus camphora L.) from China, Japan and the East Indies; in Sassafras officinale, Lavandula spica and in other Labiatae. The l-form is reported found in the essential oils of Salvia grandiflora, Matricaria parthenium, Artemisia herba alba; the optically inactive form is found in Chrysanthemum japonicum sinense. Also reported found in orange peel oil, lemon peel oil, apricot, raspberry, anise, cinnamon root bark, ginger, pepper, coriander, calamus, sweet fennel and rosemary.

Uses

(1R)-(+)-Camphor is used as a chiral intermediate and auxiliary. It is also used as a skin antipruritic and as an anti-infective agent.

Uses

(R)-(+)-Camphor is a terpenoid with a wide variety of use. (R)-(+)-Camphor has insecticidal activity and is also used as an antimicrobial agent. (R)-(+)-Camphor is used as a culinary flavouring agent in parts of asia.

Uses

analgesic, antiinfective, antipruritic

Uses

D-Camphor may be used as reference material for the quantification of the analyte in Saraca asoca and coriander using chromatography techniques.

Definition

ChEBI: The (R)- enantiomer of camphor.

Aroma threshold values

Detection at 1 to 1.29 ppm

Taste threshold values

Taste characteristics at 20 ppm: medicinal, camphoraceous, mentholic and woody.

General Description

Colorless or white crystals. Sublimes. Flash point 149°F. Burns readily with a bright, smoky flame. Penetrating aromatic odor. Pungent, aromatic taste followed by a sensation of cold.

Air & Water Reactions

Flammable. Insoluble in water.

Reactivity Profile

D-CAMPHOR is incompatible with strong oxidizing agents, strong reducing agents and chlorinated solvents.

Fire Hazard

D-CAMPHOR is combustible.

Flammability and Explosibility

Flammable

Synthesis

Natural camphor is obtained by distillation from the plants of Cinnamomum or Laurus camphora from China and Japan, together with the corresponding essential oils; the raw camphor contains several impurities. It is separated from the water and the essential oil by pressure or by centrifugation and subsequently purified by sublimation or crystallization. Synthetic camphor is prepared from pinene isolated by fractional distillation of turpentine oil; pinene is reacted to bornyl chloride with gaseous HCl under pressure and then to camphene. The distilled and purified camphene is then oxidized to camphor with Na+ or K+ bichromate in the presence of H2SO4.

Purification Methods

Crystallise it from EtOH, 50% EtOH/water, MeOH, or pet ether or from glacial acetic acid by addition of water. It can be sublimed (50o/14mm) and also fractionally crystallised from its own melt. It is steam volatile. It should be stored in tight containers as it is appreciably volatile at room temperature. The solubility is 0.1% (H2O), 100% (EtOH), 173% (Et2O) and 300%

References

[1] ELZINGA S, FISCHEDICK J, PODKOLINSKI R, et al. Cannabinoids and Terpenes as Chemotaxonomic markers in Cannabis[J]. Prime Archives in Chemistry, 2015, 14 1: 0. DOI: 10.4172/2329-6836.1000181
[2] TAE-JU PARK . Noncompetitive inhibition by camphor of nicotinic acetylcholine receptors[J]. Biochemical pharmacology, 2001, 61 7: Pages 787-793. DOI: 10.1016/s0006-2952(01)00547-0
[3] THAO ANH TRAN. Camphor Induces Proliferative and Anti-senescence Activities in Human Primary Dermal Fibroblasts and Inhibits UV-Induced Wrinkle Formation in Mouse Skin.[J]. Phytotherapy Research, 2015, 29 12: 1917-1925. DOI: 10.1002/ptr.5484
[4] E.A. LAUDE  T. J G  A H Morice. The Antitussive Effects of Menthol, Camphor and Cineole in Conscious Guinea-pigs[J]. Pulmonary pharmacology, 1994, 7 3: Pages 179-184. DOI: 10.1006/pulp.1994.1021
[5] NING ZHANG. Insecticidal, fumigant, and repellent activities of sweet wormwood oil and its individual components against red imported fire ant workers (Hymenoptera: Formicidae).[J]. Journal of Insect Science, 2014, 14. DOI: 10.1093/jisesa/ieu103
[6] DAI LU  Richard I D Jr  Jianxin Guo,  Alexandros Makriyannis*. Bornyl- and Isobornyl-Δ8-tetrahydrocannabinols: A Novel Class of Cannabinergic Ligands[J]. Journal of Medicinal Chemistry, 2008, 51 20: 6393-6399. DOI: 10.1021/jm8005299

D-CAMPHOR Preparation Products And Raw materials

Raw materials

(R)-2-Propyloctanoic acid

Preparation Products

Europium D-3-trifluoroacetylcamphorate 3-Trifluoroacetyl-D-camphor Ambroxide (R)-(+)-Bornylamine (+)-Camphor Bromide
2-Chlororesorcinol

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D-CAMPHOR Suppliers

Global Suppliers ( 400)
Supplier Tel Email Country ProdList Advantage
Jiangxi Xuesong Natural Medicinal Oil Co. LTD 18679669723 2134411736@qq.com China 282 58
Jinan Wald Chemical Co., Ltd. 0531-88773586 13210588999 304264064@qq.com China 192 58
Jiangxi yuanshangcao flavor Co., Ltd. 0796-828-2352 18979604038 1182634205@qq.com China 372 58
Jiangxi Planty Manor Health Industry Co., Ltd. 0796-18507969315 18507969315 3686433662@qq.com China 264 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Ji'an Guoguang spice factory 18607067153 18607067153 2529415945@qq.com China 215 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Supplier Advantage
Jiangxi Xuesong Natural Medicinal Oil Co. LTD 58
Jinan Wald Chemical Co., Ltd. 58
Jiangxi yuanshangcao flavor Co., Ltd. 58
Jiangxi Planty Manor Health Industry Co., Ltd. 58
Sigma-Aldrich 80
Ji'an Guoguang spice factory 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84

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View Latest Price from D-CAMPHOR manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Natural Camphor pictures 2026-09-18 Natural Camphor
464-49-3
 1KG 99% 500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
D-CAMPHOR; Camphor tree extract pictures 2026-09-11 D-CAMPHOR; Camphor tree extract
464-49-3
 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
D-Camphor pictures 2026-08-21 D-Camphor
464-49-3
 $315.00-29500.00 1kg 99% 500 Tons Hebei Dangtong Import and export Co LTD
  • D-Camphor pictures
  • D-Camphor
    464-49-3
  • $315.00-29500.00
  • 99%
  • Hebei Dangtong Import and export Co LTD

D-CAMPHOR Spectrum

D-CAMPHOR(464-49-3)MSD-CAMPHOR(464-49-3)1HNMRD-CAMPHOR(464-49-3)13CNMRD-CAMPHOR(464-49-3)IR1D-CAMPHOR(464-49-3)IR2D-CAMPHOR(464-49-3)IR3D-CAMPHOR(464-49-3)Raman

464-49-3 (D-CAMPHOR) Related Search:

methyl N,N,N-trimethyl-4-[(4,7,7-trimethyl-3-oxobicyclo[2.2.1]hept-2-ylidene)methyl]anilinium sulphate Dexketoprofen trometamol D(+)-Carvone Camphor tree, ext. TARCHONANTHUS CAMPHORATUS OIL
TARCHONANTHUS CAMPHORATUS WATER PASSIFLORA LAURIFOLIA FLOWER EXTRACT PASSIFLORA LAURIFOLIA FRUIT EXTRACT (1S)-(-)-3-Bromo Camphor, 98% min (1S)-(+)-Camphor-10-sulphonic acid
White camphor oil (1s)-(+)-3-Bromo Camphor-10-Sulfonic Acid Coumarin Europium D-3-trifluoroacetylcamphorate 3-(4-Methylbenzylidene)camphor
Europium tris[3-(heptafluoropropylhydroxymethylene)-(+)-camphorate] DL-Camphoric acid (1R)-(-)-Thiocamphor

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7,7-trimethyl-(1r)-bicyclo(2.2.1)heptan-2-on 7,7-trimethyl-(1theta)-bicyclo[2.2.1]heptan-2-on R-(+)-Camphor D-(+)-Camphor,98% CAMPHOR FLAKE, USP24 CAMPHOR, (+)-(SG) (1R,4R)-(+)-Camphor Camphor, (1R,4R)-(+)- (8CI) (+)-CAMPHOR 98+% (+)-CAMPHOR WITH GC Bicyclo2.2.1heptan-2-one, 1,7,7-trimethyl-, (1R,4R)- (+)-Camphor, (1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one (1R)-(+)-Camphor, (1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one Camphor (1 g) D(+)-CaMphor, 97% 500GR (1R)-bornan-2-one D-CAMPHOR REFERENCE SUBSTANCE FOR GAS CH (1R)-(+)-CaMphor 98% (1R)-(+)-Camphor solution bicyclo[2.2.1]heptan-2-one,1,7,7-trimethyl-,(1R)- Camphor usp CAMPHOR, (1R,4R)-(+)- camphorusp d-camphre Japanese camphor japanesecamphor (1R)-(+)-CAMPHOR (1R)-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-ONE FEMA 2230 D(-)-CAMPHOR D(+)-CAMPHOR D-CAMPHOR D-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-ONE D-2-KETO-1,7,7-TRIMETHYLNORCAMPHANE D-CAMPHOR 97+% (1r,4r)-(+)-campho 1,7,7-trimethyl-,(1R)-Bicyclo[2.2.1]heptan-2-one d-Camphor RS Medical Level D-Camphor CAS 464-49-3 with Top Quality Wholesale 100% Natural camphor powder D-Camphor D Camphor CAS 464-49-3 manufacturers NATURAL CAMPHOR POWDBR Camphor, micro analytical reagent 464-49-3 D-CAMPHOR Camphor (1087508) Camphor tree extract D(+)-Camphor, powder Camphor Powder Nat d-Camphor Solution in Methanol (+)-bornan-2-one (+)-Camphor, 10 mM in DMSO (1R)-(+)-Camphor D-Camphor (1R,4R)-1,7,7-trimethylbiscyclo[2.2.1]heptylalkane-2-one (+)-Camphor (Standard) (1R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)- CAMPHOR POWDER DAB 8 d-2-Bornanone