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AFLATOXIN B2

CAS No.
7220-81-7
Chemical Name:
AFLATOXIN B2
Synonyms
AF B2;2,3,6aB1;8,9,9aB1;AFLATOXIN B2;Aflatoxine B2;AFLATOXIN B2(RG);Aflatoxin B2;AF B2;dihydroaflatoxinb1;Dihydroaflatoxin B1;Dihydroafflatoxin B1
CBNumber:
CB0236746
Molecular Formula:
C17H14O6
Molecular Weight:
314.29
MDL Number:
MFCD00078140
MOL File:
7220-81-7.mol
Last updated:2026-01-13 11:13:15
Product description Number Pack Size Price
Aflatoxin B2 solution certified reference material, 3?μg/mL in benzene:acetonitrile (98:2), ampule of 1?mL CRM46324 1mL $84.45
Aflatoxin B2 solution 0.5?μg/mL in acetonitrile, analytical standard 34034 2ml $349
Aflatoxin B2 reference material 32755 5mg $2070
Aflatoxin B2 ≥98% 11294 1mg $72
Aflatoxin B2 ≥98% 11294 5mg $283
More product size

AFLATOXIN B2 Properties

Melting point 286-289 °C
alpha D -492° (c = 0.1 in CHCl3)
Boiling point 373.98°C (rough estimate)
Density 1.2564 (rough estimate)
refractive index 1.4800 (estimate)
Flash point 11 °C
storage temp. 2-8°C
solubility DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12 mg/ml
form Solid
color White to off-white
Water Solubility 15mg/L(temperature not stated)
Merck 13,180
BRN 1355115
Major Application cleaning products
cosmetics
food and beverages
personal care
InChI 1S/C17H14O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h6,8,17H,2-5H2,1H3/t8-,17+/m0/s1
InChIKey WWSYXEZEXMQWHT-WNWIJWBNSA-N
SMILES [H][C@@]12CCO[C@]1([H])Oc3cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc4c23
LogP 1.802 (est)
CAS DataBase Reference 7220-81-7
FDA UNII 7SKR7S646P
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H300+H310+H330-H340-H350
Precautionary statements  P201-P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  T+,T,F,Xn
Risk Statements  45-26/27/28-39/23/24/25-23/24/25-11-65-48/23/24/25-36/38-46-36-20/21/22
Safety Statements  53-36-45-36/37-26-62-28-16
RIDADR  UN 3462 6.1/PG 1
WGK Germany  3
RTECS  GY1722000
10
HazardClass  6.1(a)
PackingGroup  I
HS Code  29322090
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2
Hazardous Substances Data 7220-81-7(Hazardous Substances Data)
Toxicity LD50 orally in day old duckling: 84.8 mg/50 gm body wt (Carnaghan)
NFPA 704
1
4 1

AFLATOXIN B2 price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CRM46324 Aflatoxin B2 solution certified reference material, 3?μg/mL in benzene:acetonitrile (98:2), ampule of 1?mL 7220-81-7 1mL $84.45 2025-07-31 Buy
Sigma-Aldrich 34034 Aflatoxin B2 solution 0.5?μg/mL in acetonitrile, analytical standard 7220-81-7 2ml $349 2025-07-31 Buy
Sigma-Aldrich 32755 Aflatoxin B2 reference material 7220-81-7 5mg $2070 2024-03-01 Buy
Cayman Chemical 11294 Aflatoxin B2 ≥98% 7220-81-7 1mg $72 2024-03-01 Buy
Cayman Chemical 11294 Aflatoxin B2 ≥98% 7220-81-7 5mg $283 2024-03-01 Buy
Product number Packaging Price Buy
CRM46324 1mL $84.45 Buy
34034 2ml $349 Buy
32755 5mg $2070 Buy
11294 1mg $72 Buy
11294 5mg $283 Buy

AFLATOXIN B2 Chemical Properties,Uses,Production

Chemical Properties

off-white powder

Chemical Properties

The aflatoxins are a group of molds produced by the fungus Aspergillus flavus. They are natural contaminants of fruits, vegetables, and grains. They are also described as a series of condensed ring heterocyclic compounds. They form colorless to pale yellow crystals. Practically insoluble in water.

Uses

Aflatoxins are naturally occuring mycotoxins produced by various species of the mold Aspergillus, which can be found in legumes, corn, soybeans, rice, milk, and cheese. They are highly carcinogenic substances that are metabolized by the liver to a reactive epoxide intermediate, which produces adducts that modify DNA. Aflatoxin B1 induces transversion of G to T at codon 249 of the p53 tumor suppressor gene. This transversion is common in hepatocellular carcinoma patients living in regions with high levels of aflatoxin contamination. Aflatoxin B2 is the dihydro derivative of aflatoxin B1, a naturally occuring mycotoxin and food contaminant that is a likely pathogen that causes hepatocellular carcinoma.[Cayman Chemical]

Uses

Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects.

Uses

Aflatoxin B2 is the minor analogue of the blue fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed.

Definition

ChEBI: An aflatoxin having a hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.

Synthesis Reference(s)

[1] Gang Zhou; E. J. Corey. Short, Enantioselective Total Synthesis of Aflatoxin B2 Using an Asymmetric [3+2]-Cycloaddition Step. J. Am. Chem. Soc. 2005, 127, 34, 11958–11959.

General Description

Aflatoxin B2 is one of the fungal metabolic products produced in food and feed, contaminated byAspergillusspecies.

Safety Profile

Confirmed human carcinogen with experimental tumorigenic data. Poison by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes. See also various aflatoxins.

Synthesis

A highly enantioselective [3+2]-cycloaddition reaction of 2,3-dihydrofuran with 1,4-benzoquinones using a chiral oxazaborolidinium triflimidate as catalyst has been developed by Corey and colleagues in 2005, which allows rapid access to a variety of chiral phenolic tricycles (enantiomeric excesses ranging from 91 to 98%). The utility of this new methodology is demonstrated by a short synthesis of the important pentacyclic natural product, aflatoxin B2.[1]
AFLATOXIN B2 synthesis

Potential Exposure

Aflatoxins are a group of toxic metabolites produced by certain types of fungi. Aflatoxins are not commercially manufactured; they are naturally occurring contaminants that are formed by fungi on food during conditions of high temperatures and high humidity. Most human exposure to aflatoxins occurs through ingestion of contaminated food. The estimated amount of aflatoxins that Americans consume daily is estimated to be 0.15 0.50 μg. Grains, peanuts, tree nuts, and cottonseed meal are among the more common foods on which these fungi grow. Meat, eggs, milk, and other edible products from animals that consume aflatoxincontaminated feed may also contain aflatoxins. Aflatoxins can also be breathed in

Shipping

UN3172 Toxins, extracted from living sources, solid or liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Use of oxidizing agents, such as hydrogen peroxide or 5% sodium hypochlorite bleach. Acids and bases may also be used.

2880-58-2
7220-81-7
Synthesis of AFLATOXIN B2 from METHOXYBENZOQUINONE

AFLATOXIN B2 Preparation Products And Raw materials

Global( 155)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8753 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040 1056@dideu.com China 3982 58
Moxin Chemicals
+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10236 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514 ada@ipurechemical.com CHINA 3461 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9629 58
Shijiazhuang Tongyang Import and Export Co., LTD
18031361688; admin@sjztongyang.com China 977 58

View Lastest Price from AFLATOXIN B2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AFLATOXIN B2 pictures 2026-02-02 AFLATOXIN B2
7220-81-7
US $0.10 / KG 0.1KG 98%HPLC 20tons Shaanxi Dideu Medichem Co. Ltd
AFLATOXIN B2 pictures 2026-01-30 AFLATOXIN B2
7220-81-7
US $1.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
Aflatoxin B2 impurity pictures 2025-12-16 Aflatoxin B2 impurity
7220-81-7
US $0.00-0.00 / mg 10mg 98 10000000 Moxin Chemicals
  • AFLATOXIN B2 pictures
  • AFLATOXIN B2
    7220-81-7
  • US $0.10 / KG
  • 98%HPLC
  • Shaanxi Dideu Medichem Co. Ltd
  • AFLATOXIN B2 pictures
  • AFLATOXIN B2
    7220-81-7
  • US $1.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
AFLATOXIN B2 (6ar-cis)-hexahydro-4-methoxy ,9,9a-alpha-hexahydro-4-methoxy- 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxycyclopenta(c)furo(3’,2’:4,5)furo(2, Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxy- Dihydroafflatoxin B1 Dihydroaflatoxin B1 dihydroaflatoxinb1 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione AF B2 Aflatoxin B2;AF B2 aflatoxin b2 solution aflatoxin b2solution AFLATOXIN B2(RG) dihydroaflatoxine b1 AFLATOXIN B2 FROM ASPERGILLUS FLAVUS AFLATOXIN B2-LOESUNG 5 NG/MYL IN METHANO AFLATOXIN B(2) FROM ASPERGILLUS FLAVUS, VIAL WITH 10 MG AflatoxinB2,crystalline 3-h)(1)benzopyran-1,11-dione 4-Methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-H]chromene-1,11-dione 9aalpha-hexahydro-4-methoxy- cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6a-alpha,8 cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6aalpha,8, Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR-cis)- (6aR)-2,3,6aα,8,9,9aα-Hexahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione (6aR,9aS)-2,3,6a,8,9,9a-Hexahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione Aflatoxine B2 Aflatoxin B2 Dihydroaflatoxine B1 (6aR,9aS)-4-methoxy-2,3,9,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11(6aH,8H)-dione Aflatoxin B2, 98%, from Aspergillus flavus AflatoxinB2Solution,3mg/L Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR,9aS)- Aflatoxin B2 0.5ug/ml in ACN Aflatoxin B2 Solution in Acetonitrile, 100μg/mL 2,3,6aB1 8,9,9aB1 -hexahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione AFLATOXIN B2(RG) 10mg Aflatoxin B2 Impurity Aflatoxin B2 Aflatoxin B2 solution Aflatoxin B2 3.8μg/g in Acetonitrile 7220-81-7 C17H14O6 BioChemical Cancer Research Carcinogens Other antibiotic Chiral Reagents Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Biotoxins Mycotoxins Single component solutions