ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
- CAS No.
- 108290-86-4
- Chemical Name:
- ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
- Synonyms
- SKL228;ETHYL 2-AMINO-1H-PYRROLE-...;Ethyl 2-Aminopyrrole-3-carboxylate;2-amino-1H-pyridine-3-ethyl formate;Ethyl 2-amino-1H-pyrrol-3-carboxylate;ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE;2-amino-1H-Pyrrole-3-carboxy-lic acid ethyl ester;1H-Pyrrole-3-carboxylicacid, 2-aMino-, ethyl ester;2-amino-1H-Pyrrole-3-carboxylic acid ethyl ester (9CI ACI);1H-Pyrrole-3-carboxylic acid, 2-amino-, ethyl ester (9CI, ACI)
- CBNumber:
- CB02453239
- Molecular Formula:
- C7H10N2O2
- Molecular Weight:
- 154.17
- MDL Number:
- MFCD09953569
- MOL File:
- 108290-86-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 2-amino-1H-pyrrole-3-carboxylate 97% | AS13337 | 1g | $137 |
| Ethyl 2-amino-1H-pyrrole-3-carboxylate 97% | AS13337 | 5g | $400 |
| Ethyl 2-amino-1H-pyrrole-3-carboxylate 97% | AS13337 | 25g | $1165 |
| Ethyl 2-amino-1H-pyrrole-3-carboxylate | 121982 | 1.00g | $924 |
| Ethyl 2-amino-1H-pyrrole-3-carboxylate 97.0% | E1851 | 1g | $100 |
| More product size | |||
| Boiling point | 360.5±22.0 °C(Predicted) |
|---|---|
| Density | 1.238±0.06 g/cm3(Predicted) |
| storage temp. | -20°C, protect from light |
| pka | 18.24±0.50(Predicted) |
| Appearance | Light green to green Solid |
| InChI | InChI=1S/C7H10N2O2/c1-2-11-7(10)5-3-4-9-6(5)8/h3-4,9H,2,8H2,1H3 |
| InChIKey | XKJUSNOUOLSNJN-UHFFFAOYSA-N |
| SMILES | N1C=CC(C(OCC)=O)=C1N |
| CAS DataBase Reference | 108290-86-4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS13337 | Ethyl 2-amino-1H-pyrrole-3-carboxylate 97% | 108290-86-4 | 1g | $137 | 2026-06-04 | Buy |
| Activate Scientific | AS13337 | Ethyl 2-amino-1H-pyrrole-3-carboxylate 97% | 108290-86-4 | 5g | $400 | 2026-06-04 | Buy |
| Activate Scientific | AS13337 | Ethyl 2-amino-1H-pyrrole-3-carboxylate 97% | 108290-86-4 | 25g | $1165 | 2026-06-04 | Buy |
| Matrix Scientific | 121982 | Ethyl 2-amino-1H-pyrrole-3-carboxylate | 108290-86-4 | 1.00g | $924 | 2026-05-18 | Buy |
| Synthonix | E1851 | Ethyl 2-amino-1H-pyrrole-3-carboxylate 97.0% | 108290-86-4 | 1g | $100 | 2026-05-06 | Buy |
ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE Chemical Properties,Uses,Production
Uses
2-Amino-1H-Pyrrole-3-carboxylic acid ethyl ester acts as a reagent in the synthesis of pyrrolo pyrimidines which functions as glucocerebrosidase activators use in treatment of medical disorders.
Synthesis
107-20-0
50551-10-5
108290-86-4
1. Preparation of ethyl 2-amino-1H-pyrrole-3-carboxylate. Ethyl 3-amino-3-iminopropionate (390 mg, 3.0 mmol) was dissolved in ethyl acetate (20 mL) under argon protection with vigorous stirring. Anhydrous chloroacetaldehyde was added rapidly at 22 °C. The reaction mixture was stirred for 10 minutes and then heated to reflux for 20 minutes. Cool to room temperature and filter through a silica gel column (15 g). The residue in the reaction flask was washed several times with ethyl acetate (20 mL x 5) and the filtrates were combined. The filtrate was concentrated under reduced pressure to give 120 mg of light yellow solid product in 47% yield. The product was characterized as follows: 1H NMR (500 MHz, CDCl3) δ (ppm): 7.92 (br, 1H), 6.28 (t, J = 2.8 Hz, 1H), 6.15 (dd, J = 2.0 Hz, 1H), 4.94 (br, 2H), 4.24 (q, J = 7.1 Hz, 2H), 1.33 (t, J = 7.1 Hz, 3H).13C NMR (125 MHz, CDCl3) δ (ppm): 166.5, 145.4, 110.3, 107.5, 94.5, 59.3, 14.7.
References
[1] Journal of Heterocyclic Chemistry, 1986, vol. 23, # 5, p. 1555 - 1560
[2] Patent: WO2017/4408, 2017, A1. Location in patent: Paragraph 0087; 0089; 0090
[3] Patent: WO2016/73891, 2016, A1. Location in patent: Paragraph 00204
[4] Patent: US9447100, 2016, B2. Location in patent: Page/Page column 556; 557
ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| Shaanxi Dideu New Materials Co. Ltd | 18192503167 | 1036@dideu.com | China | 13278 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Nanjing dekerui pharmaceutical chemical co., LTD | 025-025-57059602 13913847787 | 26639969@qq.com | China | 292 | 58 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
View Lastest Price from ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
108290-86-4
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2020-01-14 | ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
108290-86-4
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
108290-86-4
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE
108290-86-4
- $9.80
- ≥99%
- Career Henan Chemical Co
108290-86-4(ETHYL 2-AMINO-1H-PYRROLE-3-CARBOXYLATE)Related Search:
1of4
