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ChemicalBook >> CAS DataBase List >>3-Bromo-[1,2,4]triazolo[4,3-a]pyridine

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine Structure
3-Bromo-[1,2,4]triazolo[4,3-a]pyridine structure
CAS No.
4922-68-3
Chemical Name:
3-Bromo-[1,2,4]triazolo[4,3-a]pyridine
Synonyms
Ponatinib Impurity 9;s-Triazolo[4,3-a]pyridine, 3-bromo-;3-bromo-[1,2,4]triazolo[4,3-a]pyridine;1,2,4-TRIAZOLO[4,3-A]PYRIDINE, 3-BROMO-
CBNumber:
CB02456245
Molecular Formula:
C6H4BrN3
Molecular Weight:
198.02
MDL Number:
MFCD11111699
MOL File:
4922-68-3.mol
MSDS File:
SDS
Last updated:2026-05-27 17:24:02
Product description Number Pack Size Price
3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 264574 50mg $368
3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 264574 100mg $496
3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 264574 250mg $672
3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 264574 500mg $885
3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 264574 1g $1168
Request For Quotation

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine Properties

Melting point 165-167 °C
Density 1.89±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 0.97±0.50(Predicted)
Appearance Light brown to brown Solid
InChI InChI=1S/C6H4BrN3/c7-6-9-8-5-3-1-2-4-10(5)6/h1-4H
InChIKey BOKHADJFZUWNSH-UHFFFAOYSA-N
SMILES C12=NN=C(Br)N1C=CC=C2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H310-H302-H315-H319
Precautionary statements  P501-P270-P262-P264-P280-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P312+P330-P302+P352+P310-P405
HS Code  2933998090

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 264574 3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 4922-68-3 50mg $368 2026-06-03 Buy
Usbiological 264574 3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 4922-68-3 100mg $496 2026-06-03 Buy
Usbiological 264574 3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 4922-68-3 250mg $672 2026-06-03 Buy
Usbiological 264574 3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 4922-68-3 500mg $885 2026-06-03 Buy
Usbiological 264574 3-Bromo[1,2,4]triazolo[4,3-a]pyridine Asreported 4922-68-3 1g $1168 2026-06-03 Buy
Product number Packaging Price Buy
264574 50mg $368 Buy
264574 100mg $496 Buy
264574 250mg $672 Buy
264574 500mg $885 Buy
264574 1g $1168 Buy

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine Chemical Properties,Uses,Production

Uses

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine is an intermediate used to prepare bi-aryl amines as mGluR5 modulators for treating gastrointestinal, urinary tract, and nervous system disorders.

Synthesis

1,7,8-triazabicyclo[4.3.0]nona-2,4,6,8-tetraene

274-80-6

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine

4922-68-3

General procedure for the synthesis of 3-bromo-[1,2,4]triazolo[4,3-a]pyridine from [1,2,4]triazolo[4,3-a]pyridine: [1,2,4]triazolo[4,3-a]pyridine (1.26 g) and N-bromosuccinimide (NBS, 1.98 g) were dissolved in chloroform, and the reaction was carried out at reflux for 5 h followed by a 14-h stand at room temperature. Upon completion of the reaction, saturated aqueous potassium carbonate (200 mL) and potassium hydroxide (20 g) were added to the mixture, and the organic layer was separated after sufficient shaking. The aqueous layer was extracted twice with dichloromethane (DCM). All organic layers were combined and dried over anhydrous sodium sulfate (Na2SO4) followed by evaporation of the solvent under vacuum to afford the target product 3-bromo-[1,2,4]triazolo[4,3-a]pyridine in 60% yield.

References

[1] Patent: EP2743266, 2014, A2. Location in patent: Page/Page column

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine synthesis

274-80-6
4922-68-3
Synthesis of 3-Bromo-[1,2,4]triazolo[4,3-a]pyridine from 1,7,8-triazabicyclo[4.3.0]nona-2,4,6,8-tetraene

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine Preparation Products And Raw materials

Raw materials

1,7,8-triazabicyclo[4.3.0]nona-2,4,6,8-tetraene Potassium carbonate Chloroform Penicillin V potassium salt N-Bromosuccinimide

Preparation Products

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine Suppliers

Global( 111)Suppliers
Supplier Tel Email Country ProdList Advantage
CHANGZHOU HARVECHEM LTD
+86-0519-88784888 +8613906120163 inquiry@harvechem.com China 311 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656 1059@dideu.com China 3587 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Suzhou Victorypharm Co.,Ltd. 		+86-13916956214 sales@victory-pharm.com China 1299 58
Coresyn Pharmatech Co., Ltd. 		+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9984 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 		+8618829768577 gao490372054@gamil.com China 1249 58
Supplier Advantage
CHANGZHOU HARVECHEM LTD
58
Shaanxi Dideu Medichem Co. Ltd 		58
Standardpharm Co. Ltd. 		58
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Suzhou Victorypharm Co.,Ltd. 		58
Coresyn Pharmatech Co., Ltd. 		58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 		58

View Lastest Price from 3-Bromo-[1,2,4]triazolo[4,3-a]pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Bromo-[1,2,4]triazolo[4,3-a]pyridine pictures 2025-12-12 3-Bromo-[1,2,4]triazolo[4,3-a]pyridine
4922-68-3
 $1.00-2.10 1KG 99% 20000KG Shaanxi Dideu Medichem Co. Ltd
1,2,4-TRIAZOLO[4,3-A]PYRIDINE, 3-BROMO- pictures 2020-01-05 1,2,4-TRIAZOLO[4,3-A]PYRIDINE, 3-BROMO-
4922-68-3
 $9.80 1g ≥99% 100kg Career Henan Chemical Co

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine Spectrum

3-Bromo-[1,2,4]triazolo[4,3-a]pyridine(4922-68-3)1HNMR

4922-68-3(3-Bromo-[1,2,4]triazolo[4,3-a]pyridine)Related Search:

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Ponatinib Impurity 10 3-bromo-4-methyl-1,2,4-triazole 3-Bromo-[1,2,4]triazolo[4,3-a]pyridine

1of4

1,2,4-TRIAZOLO[4,3-A]PYRIDINE, 3-BROMO- 3-bromo-[1,2,4]triazolo[4,3-a]pyridine s-Triazolo[4,3-a]pyridine, 3-bromo- Ponatinib Impurity 9 4922-68-3 Heterocycle-Pyridine series