N-Methyl-2-aminopyridine-3-carboxamide
- CAS No.
- 870997-87-8
- Chemical Name:
- N-Methyl-2-aminopyridine-3-carboxamide
- Synonyms
- N-Methyl-2-aminonicotinamide;2-Amino-N-methylnicotinamide;N-methyl-2-amino-3-nicotinamide;2-amino-N-methylpyridine-3-carboxamide;N-Methyl-2-aminopyridine-3-carboxamide;3-Pyridinecarboxamide,2-amino-N-methyl-;N-Methyl-2-aminopyridine-3-carboxamide ISO 9001：2015 REACH
- CBNumber:
- CB02462174
- Molecular Formula:
- C7H9N3O
- Molecular Weight:
- 151.17
- MDL Number:
- MOL File:
- 870997-87-8.mol
- MSDS File:
- SDS
| Melting point | 149 - 151°C |
|---|---|
| Boiling point | 373.1±27.0 °C(Predicted) |
| Density | 1.206 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| form | Solid |
| pka | 14.44±0.46(Predicted) |
| color | White to Off-White |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P280 |
N-Methyl-2-aminopyridine-3-carboxamide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-A636380-500MG | 2-Amino-N-methylpyridine-3-carboxamide | 870997-87-8 | 500mg | $167 | 2026-06-03 | Buy |
| TRC | TRC-A636380-250MG | 2-Amino-N-methylpyridine-3-carboxamide | 870997-87-8 | 250mg | $103 | 2026-06-03 | Buy |
| TRC | TRC-A636380-100MG | 2-Amino-N-methylpyridine-3-carboxamide | 870997-87-8 | 100mg | $59 | 2026-06-03 | Buy |
| Activate Scientific | AS114918 | 2-Amino-N-methylnicotinamide 95% | 870997-87-8 | 1g | $94 | 2026-06-04 | Buy |
| Activate Scientific | AS114918 | 2-Amino-N-methylnicotinamide 95% | 870997-87-8 | 5g | $247 | 2026-06-04 | Buy |
N-Methyl-2-aminopyridine-3-carboxamide Chemical Properties, Uses, Production
Uses
2-Amino-N-methylpyridine-3-carboxamide is used in preparation of triazolopyrazine derivatives and analogs for use as c-MET kinase activity inhibitors.
Synthesis
5345-47-1
593-51-1
870997-87-8
To 2-aminonicotinic acid (2.0 g, 14.5 mmol) and methylamine hydrochloride (1.47 g, 1.5 eq.) were added EDC (4.49 g, 1.5 eq.), HOBt (2.35 g, 1.2 eq.), and DIEA (7.6 mL, 3.0 eq.) sequentially in DMF (20 mL). The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the crude product was concentrated and the residue was dissolved in EtOAc. The organic phase was washed with saturated NaHCO3 solution. After removing the solvent under reduced pressure, the crude product was purified by silica gel column chromatography (eluent: 0%-20% MeOH/DCM) to afford the target compound 2-amino-N-methylnicotinamide (2.16 g, isolated yield 98%).
References
[1] Patent: WO2008/115369, 2008, A2. Location in patent: Page/Page column 130
N-Methyl-2-aminopyridine-3-carboxamide Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Yancheng KangdiSen Pharmaceutical Co., Ltd. | 13812573443;18052965989 | tongbenwan22@163.com | China | 1975 | 55 |
| Nanjing Abix Biochemical Technology Co., Ltd. | 025-87193546 18652950785; | chemweiao@163.com | China | 9009 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Dalian lichuang Chemical Co., Ltd | 0411-0411-00000000 13644282108 | 3500508746@qq.com | China | 2942 | 55 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Suzhou Nuoouman Biological Technology Co., Ltd. | 15026866316 | 180642609@qq.com | China | 4966 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
View Latest Price from N-Methyl-2-aminopyridine-3-carboxamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | N-Methyl-2-aminopyridine-3-carboxamide
870997-87-8
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd |
-
- N-Methyl-2-aminopyridine-3-carboxamide
870997-87-8
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
