Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
- CAS No.
- 231285-86-2
- Chemical Name:
- Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
- Synonyms
- 1-methyl-5-trifluoromethyl-1H-pyrazole-4-ethyl carboxylate;4-(Ethoxycarbonyl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole;Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate;Ethyl 2-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate;Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 97%;1-Methyl-5-trifluoromethylpyrazole-4-carboxylic acid ethyl ester;1H-Pyrazole-4-carboxylicacid, 1-methyl-5-(trifluoromethyl)-, ethyl ester;1H-pyridineazole-4-carboxylic acid,1-methyl-5-(trifluoromethyl)-,ethyl ester
- CBNumber:
- CB02474515
- Molecular Formula:
- C8H9F3N2O2
- Molecular Weight:
- 222.16
- MDL Number:
- MFCD00277430
- MOL File:
- 231285-86-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Ethyl 5-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate Asreported | 275854 | 500mg | $355 |
| Ethyl 5-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate Asreported | 275854 | 1g | $615 |
| Ethyl 5-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate Asreported | 275854 | 2g | $864 |
| Ethyl 5-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate Asreported | 275854 | 5g | $1218 |
| Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 97% | PC0541 | 1g | $74 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HS Code | 29333990 |
Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 275854 | Ethyl 5-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate Asreported | 231285-86-2 | 500mg | $355 | 2026-06-03 | Buy |
| Usbiological | 275854 | Ethyl 5-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate Asreported | 231285-86-2 | 1g | $615 | 2026-06-03 | Buy |
| Usbiological | 275854 | Ethyl 5-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate Asreported | 231285-86-2 | 2g | $864 | 2026-06-03 | Buy |
| Usbiological | 275854 | Ethyl 5-(trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate Asreported | 231285-86-2 | 5g | $1218 | 2026-06-03 | Buy |
| Apolloscientific | PC0541 | Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 97% | 231285-86-2 | 1g | $74 | 2026-06-04 | Buy |
Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate Chemical Properties,Uses,Production
Chemical Properties
White solid
Synthesis
571-55-1
60-34-4
231285-86-2
General procedure: Intermediate 65a: Synthesis of ethyl 1-methyl-5-(trifluoromethyl)pyrazole-4-carboxylate 1. methylhydrazine (1.2 mL, 22.7 mmol) was slowly added to a mixture of concentrated hydrochloric acid. 2. HCl (1.95 mL, 23.7 mmol) and EtOH (1.9 mL) were added to the mixture at 0 °C and stirred at that temperature for 30 min. 3. the reaction mixture was diluted with EtOH (7.7 mL). 4. the resulting ethanol solution of methylhydrazine hydrochloride was slowly added to a solution of ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobutanoate (4.00 mL, 20.7 mmol) in EtOH (58 mL) at 0°C. 5. The reaction mixture was allowed to warm slowly to room temperature and stirred overnight. 6. The light yellow solution was concentrated in vacuum and the residue was suspended in water (20 mL). 7. Alkalize the aqueous phase with saturated aqueous NaHCO3, add Na2CO3 (20 mL) and extract with EtOAc (3 x 30 mL). 8. The organic layers were combined, washed with brine (30 mL), dried over Na2SO4, filtered and concentrated in vacuum. 9. The residue was purified by column chromatography (eluent: 0-50% EtOAc in heptane) to afford ethyl 1-methyl-5-(trifluoromethyl)pyrazole-4-carboxylate (2.91 g, 13.09 mmol, 64% yield) as a colorless oil. Characterization data: 1H NMR (CDCl3, 400 MHz) δ/ppm: 7.93 (1H, s), 4.34 (2H, q, J = 7.2 Hz), 4.09 (3H, s), 1.37 (3H, t, J = 7.2 Hz). 19F NMR (CDCl3, 400 MHz) δ/ppm: -57.1. MS (Method 2): RT: 1.62 min, m/z 223.0 [M + H]+.
References
[1] Patent: WO2016/51193, 2016, A1. Location in patent: Paragraph 00615; 00616; 00617
[2] Patent: CN104829605, 2018, B. Location in patent: Paragraph 0048-0051
Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Hunan Jibang Biological Technology Co., LTD | +8613776644403 | sales02@kingboomtech.com | China | 1804 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49967 | 58 |
View Lastest Price from Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-01 | Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
231285-86-2
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
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- Ethyl 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
231285-86-2
- $1.00
- 99%
- Career Henan Chemical Co
