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tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate structure

CAS No.: 1095708-32-9

Chemical Name:: tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate

Synonyms: Boc-2-AMinopyridine-4-boronic acid pinacol ester;2-boc-aminopyridine-4-borate frequency alcohol ester;2-(tert-Butoxycarbonylamino)pyridine-4-boronic acid pinacol ...;2-(tert-ButoxycarbonylaMino)pyridine-4-boronic acid pinacol ester;(2-((TERT-BUTOXYCARBONYL)AMINO)PYRIDIN-4-YL)BORONIC ACID PINACOL ESTER;tert-butyl N-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate;2-(tert-Butoxycarbonylamino)pyridine-4-boronic acid pinacol ester - [A12056];N-tert-butyl-N-[3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbaMate;ert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate;tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate

CBNumber:: CB02500414

Molecular Formula:: C16H25BN2O4

Molecular Weight:: 320.19

MDL Number:: MFCD12032217

MOL File:: 1095708-32-9.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:41

Product description	Number	Pack Size	Price
Boc-2-aminopyridine-4-boronicAcidPinacolEster	B621203	100mg	$85
Boc-2-aminopyridine-4-boronicAcidPinacolEster	B621203	25mg	$45
tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate 95+%	093840	250mg	$515
tert-Butyl4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylcarbamate	Y7027	5g	$736
2-(tert-Butoxycarbonylamino)pyridine-4-boronicacidpinacolester 97.0%	A12056	10g	$930
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tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate Properties

Boiling point	400.7±30.0 °C(Predicted)
Density	1.10
storage temp.	Sealed in dry,Store in freezer, under -20°C
pka	12.66±0.70(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B621203	Boc-2-aminopyridine-4-boronicAcidPinacolEster	1095708-32-9	100mg	$85	2021-12-16	Buy
TRC	B621203	Boc-2-aminopyridine-4-boronicAcidPinacolEster	1095708-32-9	25mg	$45	2021-12-16	Buy
Matrix Scientific	093840	tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate 95+%	1095708-32-9	250mg	$515	2021-12-16	Buy
AK Scientific	Y7027	tert-Butyl4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylcarbamate	1095708-32-9	5g	$736	2021-12-16	Buy
Synthonix	A12056	2-(tert-Butoxycarbonylamino)pyridine-4-boronicacidpinacolester 97.0%	1095708-32-9	10g	$930	2021-12-16	Buy

Product number	Packaging	Price	Buy
B621203	100mg	$85	Buy
B621203	25mg	$45	Buy
093840	250mg	$515	Buy
Y7027	5g	$736	Buy
A12056	10g	$930	Buy

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate Chemical Properties,Uses,Production

Synthesis

207799-10-8

73183-34-3

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin
-2-yl]carbamate

1095708-32-9

A reaction mixture was prepared in dimethyl sulfoxide (8 mL) with 2-Boc amine-4-bromopyridine (0.494 g, 1.81 mmol), pinacol ester of bisboronic acid (1.4 g, 5.51 mmol) and potassium acetate (0.535 g, 5.45 mmol). The mixture was purged with nitrogen for 10 min to deoxygenate. Subsequently, [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloride (0.150 g, 0.184 mmol) was added and again purged with nitrogen for 5 min. Under nitrogen protection, the reaction mixture was heated to 85 °C and stirred for 1 hour. Upon completion of the reaction, the mixture was diluted with ethyl acetate (15 mL) and washed with 0.2 M aqueous hydrochloric acid (10 mL). Note that some of the product may be present in the aqueous layer. Carefully adjust the pH of the aqueous layer to about 6 with saturated aqueous sodium carbonate, and then extract the product from the aqueous layer with ethyl acetate (10 mL). The organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated in vacuum to afford 2-(Boc-amino)pyridine-4-boronic acid pinacol ester as a white solid (0.44 g, 76% yield). The product was characterized by 1H NMR (DMSO-d6) and LCMS: 1H NMR (DMSO-d6) δ 1.29 (s, 12H), 1.45 (s, 9H), 7.15-7.17 (d, 1H), 8.07 (s, 1H), 8.24-8.25 (d, 1H), 9.77 (s, 1H); LCMS Rt = 0.68 min, MS m/z 183.1 [M+H]+.

References

[1] Journal of Medicinal Chemistry, 2017, vol. 60, # 13, p. 5613 - 5637
[2] Patent: WO2012/4714, 2012, A2. Location in patent: Page/Page column 62
[3] Patent: US2014/194443, 2014, A1. Location in patent: Paragraph 0543-0545
[4] Patent: WO2014/108337, 2014, A1. Location in patent: Page/Page column 69; 70
[5] Patent: US2010/179154, 2010, A1. Location in patent: Page/Page column 29

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate Preparation Products And Raw materials

Raw materials

TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE Bis(pinacolato)diboron Potassium Acetate Dimethyl sulfoxide

Preparation Products

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate Suppliers

Global( 106)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 +86-17392581500	1015@dideu.com	China	3992	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
Labnetwork lnc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Nanjing Doge Biomedical Technology Co., Ltd	58

View Lastest Price from tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-10	tert-butyl N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate 1095708-32-9	US $1.00 / KG	1KG	98% HPLC	10 tons/month	Career Henan Chemical Co

tert-butyl N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate
1095708-32-9
US $1.00 / KG
98% HPLC
Career Henan Chemical Co

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate Spectrum

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate (1095708-32-9)¹HNMR

1095708-32-9(tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate )Related Search:

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N-BOC-4-broMo-3-Methylaniline 2-BOC-AMINO-4-BROMOTOLUENE (6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER (5-BROMO-PYRIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER CARBAMIC ACID, (5-BROMO-4-METHYL-2-PYRIDINYL)-,1,1-DIMETHYLETHYL ESTER

(2-Bromo-5-methyl-phenyl)-carbamic acid tert-butyl ester tert-butyl 4-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylcarbaMate Tert-butyl (4-bromo-2,3-dimethylphenyl)carbamate tert-butyl N-[3-(4-amino-1H-pyrazol-1-yl)propyl]carbamate N-(3-Iodo-5-methylpyridin-2-yl)pivalamide

tert-Butyl (2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)biscarbamate Carbamic acid, N-(4-bromo-2,5-difluorophenyl)-, 1,1-dimethylethyl ester Carbamic acid, N-(4-bromo-2,6-difluorophenyl)-, 1,1-dimethylethyl ester

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tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate N-tert-butyl-N-[3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbaMate 2-(tert-ButoxycarbonylaMino)pyridine-4-boronic acid pinacol ester Boc-2-AMinopyridine-4-boronic acid pinacol ester tert-butyl N-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate [4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-carbamic acid tert-butyl ester 97% (2-((TERT-BUTOXYCARBONYL)AMINO)PYRIDIN-4-YL)BORONIC ACID PINACOL ESTER tert-butyl (4-(hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boranyl)pyridin-2-yl)carbamate tert-butyl N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate Carbamic acid, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-, 1,1-dimethylethyl ester 2-(tert-Butoxycarbonylamino)pyridine-4-boronic acid pinacol ... 1,1-Dimethylethyl N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]carbamate 2-boc-aminopyridine-4-borate frequency alcohol ester ert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate 2-(tert-Butoxycarbonylamino)pyridine-4-boronic acid pinacol ester - [A12056] 1095708-32-9