Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-
- CAS No.
- 148553-51-9
- Chemical Name:
- Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-
- Synonyms
- (R)-3-(AMinoMethyl)-5-Methylhexanoic acid;EOS-60963;PD 144550;ent-Pregabalin;PGL-R-isomer(IMP);Pregabalin R-Isomer;Pregaballin R-Isomer;Pregabalin IMpurity V;Pregabalin EP impurity B;(R)-Isomer of Pregabalin
- CBNumber:
- CB02519117
- Molecular Formula:
- C8H17NO2
- Molecular Weight:
- 159.23
- MDL Number:
- MFCD08277235
- MOL File:
- 148553-51-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Pregabalin Related Compound A certified reference material, pharmaceutical secondary standard | PHR8629 | 50 mg | $757 |
| Pregabalin Related Compound A certified reference material, pharmaceutical secondary standard | PHR8629 | 1 unit | $700 |
| (R)-Pregabalin | 019923 | 5mg | $531 |
| Pregabalin USP related compound A | FP27138 | 50mg | $389.5 |
| Pregabalin USP related compound A | FP27138 | 100mg | $649 |
| More product size | |||
| Boiling point | 274.0±23.0 °C(Predicted) |
|---|---|
| Density | 0.997±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| pka | 4.23±0.10(Predicted) |
| form | Solid |
| color | White |
| Major Application | pharmaceutical |
| InChI | 1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m1/s1 |
| InChIKey | AYXYPKUFHZROOJ-SSDOTTSWSA-N |
| SMILES | [N+H3]C[C@H](CC(C)C)CC(=O)[O-] |
| FDA UNII | 81R7ZI0HBG |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS08,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H318-H361 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P280-P305+P351+P338-P310 |
| target organs | Central nervous system |
| WGK Germany | WGK 3 |
| HS Code | 2922493800 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Repr. 2 STOT SE 3 |
Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR8629 | Pregabalin Related Compound A certified reference material, pharmaceutical secondary standard | 148553-51-9 | 50 mg | $757 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR8629 | Pregabalin Related Compound A certified reference material, pharmaceutical secondary standard | 148553-51-9 | 1 unit | $700 | 2025-07-31 | Buy |
| Usbiological | 019923 | (R)-Pregabalin | 148553-51-9 | 5mg | $531 | 2026-06-03 | Buy |
| Biosynth | FP27138 | Pregabalin USP related compound A | 148553-51-9 | 50mg | $389.5 | 2026-06-04 | Buy |
| Biosynth | FP27138 | Pregabalin USP related compound A | 148553-51-9 | 100mg | $649 | 2026-06-04 | Buy |
Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
(R)-Pregabalin is a GABA analogue used as an anticonvulsant, Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia (less potent than the S-Enantiomer).
Synthesis
Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- was synthesized by the resolution of racemic amide with (S)-1-phenylethylamine in chloroform and ethanol followed by Hofmann reaction[1].
References
[1] Sripathi, S., Somesetti, N. R., Veeramalla, R., Challa, N. R., Peddi, S., Karnati, V. R. (2010). Synthesis and characterization of impurities of an anticonvulsant drug, Pregabalin. Arkivoc, 2010 1. https://doi.org/10.3998/ARK.5550190.0011.A22
Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +8617392709771 | 1097@dideu.com | China | 3992 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| Hong Kong Tiansheng New Material Trading Co., Ltd | +8617320695765 | zxx@hktiansheng.com | China | 973 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
View Lastest Price from Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-24 | Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-
148553-51-9
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | ||
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2022-02-25 | (R)-Pregabalin
148553-51-9
|
$28.00 | 1KG | 99% | 1 ton | Hong Kong Tiansheng New Material Trading Co., Ltd | |
![]() |
2022-02-25 | (R)-Pregabalin
148553-51-9
|
$11.36 | 1Kg/Bag | 99% | 3tons | Hong Kong Tiansheng New Material Trading Co., Ltd |
-

- Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-
148553-51-9
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-

- (R)-Pregabalin
148553-51-9
- $28.00
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-

- (R)-Pregabalin
148553-51-9
- $11.36
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
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