ChemicalBook >> CAS DataBase List >>2,3-Difluorophenylacetic acid

2,3-Difluorophenylacetic acid

CAS No.
145689-41-4
Chemical Name:
2,3-Difluorophenylacetic acid
Synonyms
Acid 2,3-difluoro;RARECHEM AL BO 0630;2,3-Difluorophenylacetic acid;2,3-DIFLUOROBENZENEACETIC ACID;2,3-Difluorophenylaceticacid97%;2,3-DifluorophenylaceticAcid>Benzeneacetic acid, 2,3-difluoro-;2-(2,3-DIFLUOROPHENYL)ACETIC ACID;2 3-DIFLUOROPHENYLACETIC ACID 97%;2,3-Difluorophenylacetic acid ISO 9001:2015 REACH
CBNumber:
CB0252890
Molecular Formula:
C8H6F2O2
Molecular Weight:
172.13
MDL Number:
MFCD00040968
MOL File:
145689-41-4.mol
MSDS File:
SDS
Last updated:2026-01-13 11:13:03
Product description Number Pack Size Price
2,3-Difluorophenylacetic acid 97% 290416 1g $63.5
2,3-Difluorophenylacetic Acid >98.0%(GC)(T) D3889 1g $125
2,3-Difluorophenylacetic Acid >98.0%(GC)(T) D3889 5g $602
2,3-Difluorophenylacetic Acid D451193 500mg $65
2,3-Difluorophenylacetic Acid D451193 250mg $55
More product size

2,3-Difluorophenylacetic acid Properties

Melting point 116-119 °C (lit.)
Boiling point 258.1±25.0 °C(Predicted)
Density 1.373±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form Crystalline Powder
pka 3.81±0.10(Predicted)
color White to off-white
InChI InChI=1S/C8H6F2O2/c9-6-3-1-2-5(8(6)10)4-7(11)12/h1-3H,4H2,(H,11,12)
InChIKey UXSQXUSJGPVOKT-UHFFFAOYSA-N
SMILES C1(CC(O)=O)=CC=CC(F)=C1F
CAS DataBase Reference 145689-41-4(CAS DataBase Reference)
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
target organs Respiratory system
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36
WGK Germany  3
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29163990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2,3-Difluorophenylacetic acid price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 290416 2,3-Difluorophenylacetic acid 97% 145689-41-4 1g $63.5 2023-01-07 Buy
TCI Chemical D3889 2,3-Difluorophenylacetic Acid >98.0%(GC)(T) 145689-41-4 1g $125 2025-07-31 Buy
TCI Chemical D3889 2,3-Difluorophenylacetic Acid >98.0%(GC)(T) 145689-41-4 5g $602 2022-04-27 Buy
TRC D451193 2,3-Difluorophenylacetic Acid 145689-41-4 500mg $65 2021-12-16 Buy
TRC D451193 2,3-Difluorophenylacetic Acid 145689-41-4 250mg $55 2021-12-16 Buy
Product number Packaging Price Buy
290416 1g $63.5 Buy
D3889 1g $125 Buy
D3889 5g $602 Buy
D451193 500mg $65 Buy
D451193 250mg $55 Buy

2,3-Difluorophenylacetic acid Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

2,3-Difluorophenylacetic acid may be used in chemical synthesis.

Synthesis

Methyl (2,3-difluorophenyl)acetate

1036273-31-0

2,3-Difluorophenylacetic acid

145689-41-4

Example 19: Synthesis of 2-(2,3-difluorophenyl)acetic acid Using methyl 2,3-difluorophenylacetate (CAS: 1036273-31-0) as a raw material, the following was performed: 1. 10 mL of water and 0.8 mL of 30% sodium hydroxide solution were added to 0.3 g of methyl 2,3-difluorophenylacetate. 2. the reaction mixture was stirred at 60 °C for 1 h until the reaction was complete. 3. After completion of the reaction, the mixture was acidified to pH=1 with concentrated hydrochloric acid. 4. The product was separated by filtration to afford 2-(2,3-difluorophenyl)acetic acid as a white solid in a yield of 0.2 g (72% yield). Product Characterization: 1H-NMR (300 MHz, CDCl3): δ (ppm): 3.75 (s, 2H); 7.01-7.06 (m, 3H); 9.4 (bs, 1H).

References

[1] Patent: WO2008/78350, 2008, A2. Location in patent: Page/Page column 23

2,3-Difluorophenylacetic acid Preparation Products And Raw materials

Global( 265)Suppliers
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View Lastest Price from 2,3-Difluorophenylacetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3-Difluorophenylacetic acid pictures 2026-01-05 2,3-Difluorophenylacetic acid
145689-41-4
US $1.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2,3-Difluorophenylacetic acid pictures 2026-01-05 2,3-Difluorophenylacetic acid
145689-41-4
US $0.00-0.00 / KG 10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
2,3-Difluorophenylacetic acid pictures 2025-05-26 2,3-Difluorophenylacetic acid
145689-41-4
US $3.00 / kg 1kg 0.99 1000 Hebei Fengjia New Material Co., Ltd
RARECHEM AL BO 0630 2-(2,3-DIFLUOROPHENYL)ACETIC ACID 2,3-DIFLUOROBENZENEACETIC ACID 2 3-DIFLUOROPHENYLACETIC ACID 97% 2,3-Difluorophenylaceticacid97% 2,3-Difluorophenylacetic acid Benzeneacetic acid, 2,3-difluoro- Acid 2,3-difluoro 2,3-DifluorophenylaceticAcid> 2,3-Difluorophenylacetic acid ISO 9001:2015 REACH 145689-41-4 F2C6H3CH2CO2H Building Blocks Carboxylic Acids Carbonyl Compounds C8 Organic Building Blocks Aromatic Phenylacetic Acids and Derivatives Phenylacetic acid C8 Carbonyl Compounds Carboxylic Acids Fluorobenzene Series Phenylacetic acid series