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ChemicalBook >> CAS DataBase List >>2,4-Dichloro-5-ethoxymethyl-pyrimidine

2,4-Dichloro-5-ethoxymethyl-pyrimidine

2,4-Dichloro-5-ethoxymethyl-pyrimidine Structure
2,4-Dichloro-5-ethoxymethyl-pyrimidine structure
CAS No.
7627-39-6
Chemical Name:
2,4-Dichloro-5-ethoxymethyl-pyrimidine
Synonyms
2,4-Dichloro-5-(ethoxymethyl);2,4-Dichloro-5-ethoxymethyl-pyrimidine;Pyrimidine, 2,4-dichloro-5-(ethoxymethyl)-;2,4-dichloro-5-(ethoxymethyl)pyrimidine - [D87388]
CBNumber:
CB02531793
Molecular Formula:
C7H8Cl2N2O
Molecular Weight:
207.06
MDL Number:
MFCD18837148
MOL File:
7627-39-6.mol
MSDS File:
SDS
Last updated:2026-05-27 17:25:16
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2,4-Dichloro-5-ethoxymethyl-pyrimidine Properties

Boiling point 274℃
Density 1.331
Flash point 119℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -3.11±0.29(Predicted)
Appearance Off-white to light brown Solid-Liquid Mixture

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Warning
Hazard statements  H226
Precautionary statements  P501-P240-P210-P233-P243-P241-P242-P280-P370+P378-P303+P361+P353-P403+P235

2,4-Dichloro-5-ethoxymethyl-pyrimidine price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS47091 2,4-Dichloro-5-(ethoxymethyl)pyrimidine 97% 7627-39-6 1g $56 2026-06-04 Buy
Activate Scientific AS47091 2,4-Dichloro-5-(ethoxymethyl)pyrimidine 97% 7627-39-6 5g $181 2026-06-04 Buy
Activate Scientific AS47091 2,4-Dichloro-5-(ethoxymethyl)pyrimidine 97% 7627-39-6 25g $760 2026-06-04 Buy
Synthonix D87388 2,4-dichloro-5-(ethoxymethyl)pyrimidine 95% 7627-39-6 1g $40 2026-05-06 Buy
Synthonix D87388 2,4-dichloro-5-(ethoxymethyl)pyrimidine 95% 7627-39-6 5g $120 2026-05-06 Buy
Product number Packaging Price Buy
AS47091 1g $56 Buy
AS47091 5g $181 Buy
AS47091 25g $760 Buy
D87388 1g $40 Buy
D87388 5g $120 Buy

2,4-Dichloro-5-ethoxymethyl-pyrimidine Chemical Properties, Uses, Production

Synthesis

5-(ethoxymethyl)pyrimidine-2,4(1H,3H)-dione

89943-60-2

2,4-Dichloro-5-ethoxymethyl-pyrimidine

7627-39-6

Phosphoryl chloride (0.67 mL, 7.35 mmol) was slowly added to a suspension of 5-(ethoxymethyl)pyrimidine-2,4(1H,3H)-dione (0.5 g, 2.94 mmol) in toluene (1 mL) at 0 °C and stirred for 15 min. Subsequently, Hünig base (N,N-diisopropylethylamine, 0.77 mL, 4.41 mmol) was added dropwise to the reaction mixture at 0 °C. The reaction mixture was warmed to 120 °C and stirred for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and slowly poured into a pre-cooled two-phase mixture of ethyl acetate and water (1:1, v/v) at 0°C for 45 minutes. Stirring was continued at the same temperature for 1.5 hours. The reaction mixture was extracted with ethyl acetate, the organic layers were combined, washed sequentially with water and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to give the crude product INT-60 (0.40 g, 65% yield) as a brown liquid. The crude product was further purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (30:1 to 20:1). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 8.67 (s, 1H), 4.56 (s, 2H), 3.66 (q, J=7.2 Hz, 2H), 1.30 (t, J=7.2 Hz, 3H).

References

[1] Patent: US2016/75720, 2016, A1. Location in patent: Paragraph 0331; 0333

2,4-Dichloro-5-ethoxymethyl-pyrimidine Preparation Products And Raw materials

Raw materials

Ethanol 5-(ethoxymethyl)pyrimidine-2,4(1H,3H)-dione 2,4-Dichloro-5-(iodomethyl)pyrimidine N,N-Diisopropylethylamine trichlorophosphate

Preparation Products

2,4-Dichloro-5-ethoxymethyl-pyrimidine Suppliers

Global Suppliers ( 47)
Supplier Tel Email Country ProdList Advantage
Tongchuang Pharma(Suzhou). Co., Ltd. 0512-63263366 18912765016 tongtf110@sina.com China 984 62
Amber MolTech LLC 086-010-62176588 amber@jyamber.com China 10150 56
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Biyu Biotechnology (Shanghai) Co., ltd 021-26018599 China 269 56
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Suzhou JingTong Pharmaceutical Co., Ltd. 13675155016 tongtf110@sina.com China 963 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Shanghai ZiHao Pharmaceutical Co., Ltd. 021-13482410-12 13482410112; 362383684@qq.com China 751 58
Supplier Advantage
Tongchuang Pharma(Suzhou). Co., Ltd. 62
Amber MolTech LLC 56
Shanghai Topbiochem Technology Co., Ltd 58
Bide Pharmatech Ltd. 60
Biyu Biotechnology (Shanghai) Co., ltd 56
ShangHai Biochempartner Co.,Ltd 62
Suzhou JingTong Pharmaceutical Co., Ltd. 55
Amadis Chemical Company Limited 58
Aikon International Limited 58
Shanghai ZiHao Pharmaceutical Co., Ltd. 58

View Latest Price from 2,4-Dichloro-5-ethoxymethyl-pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-Dichloro-5-(ethoxymethyl)pyrimidine pictures 2020-05-17 2,4-Dichloro-5-(ethoxymethyl)pyrimidine
7627-39-6
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd

2,4-Dichloro-5-ethoxymethyl-pyrimidine Spectrum

2,4-Dichloro-5-ethoxymethyl-pyrimidine(7627-39-6)1HNMR

7627-39-6 (2,4-Dichloro-5-ethoxymethyl-pyrimidine) Related Search:

Tungsten 2,4-Dichloro-5-methoxymethyl-pyrimidine 5-PyriMidineMethanol, 2,4-dichloro- ethyl 2,4-dichloropyrimidine-5-carboxylate Methyl2,4-Dichloropyrimidine-5-carboxylate
(2,4-Dichloro-5-pyrimidinyl)methyl Acetate

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2,4-Dichloro-5-ethoxymethyl-pyrimidine 2,4-Dichloro-5-(ethoxymethyl) Pyrimidine, 2,4-dichloro-5-(ethoxymethyl)- 2,4-dichloro-5-(ethoxymethyl)pyrimidine - [D87388] 7627-39-6