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7-Bromo-3,4-dihydro-1H-quinolin-2-one

7-Bromo-3,4-dihydro-1H-quinolin-2-one structure

CAS No.: 14548-51-7

Chemical Name:: 7-Bromo-3,4-dihydro-1H-quinolin-2-one

Synonyms: 7-broMo-3,4-dihydroquinolin-2(1H)-one;7-Bromo-3,4-dihydro-1H-quinolin-2-one;7-Bromo-3,4-dihydro-2(1H)-quinolinone;7-Bromo-3,4-dihydro-1H-quinoline-2-one;2(1H)-Quinolinone, 7-bromo-3,4-dihydro-;7-BROMO-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 1G;7-BROMO-1,2,3,4-TETRAHYDRO-2-QUINOLINONE

CBNumber:: CB02565129

Molecular Formula:: C9H8BrNO

Molecular Weight:: 226.07

MDL Number:: MFCD09878790

MOL File:: 14548-51-7.mol

Last updated:2026-05-27 17:34:43

Product description	Number	Pack Size	Price
7-BROMO-1,2,3,4-TETRAHYDRO-2-QUINOLINONE 97%	56602	1G	$85
7-BROMO-1,2,3,4-TETRAHYDRO-2-QUINOLINONE 97%	56602	5G	$310
7-Bromo-3,4-dihydro-1H-quinolin-2-one	PAA54851	10g	$584.1
7-Bromo-3,4-dihydro-1H-quinolin-2-one	PAA54851	25g	$843.75
7-Bromo-3,4-dihydro-1H-quinolin-2-one	PAA54851	50g	$1298
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7-Bromo-3,4-dihydro-1H-quinolin-2-one Properties

Boiling point	359.1±42.0 °C(Predicted)
Density	1.559±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	14.08±0.20(Predicted)
Appearance	White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H335-H319-H302-H315
Precautionary statements	P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

7-Bromo-3,4-dihydro-1H-quinolin-2-one price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AstaTech	56602	7-BROMO-1,2,3,4-TETRAHYDRO-2-QUINOLINONE 97%	14548-51-7	1G	$85	2026-04-30	Buy
AstaTech	56602	7-BROMO-1,2,3,4-TETRAHYDRO-2-QUINOLINONE 97%	14548-51-7	5G	$310	2026-04-30	Buy
Biosynth	PAA54851	7-Bromo-3,4-dihydro-1H-quinolin-2-one	14548-51-7	10g	$584.1	2026-06-04	Buy
Biosynth	PAA54851	7-Bromo-3,4-dihydro-1H-quinolin-2-one	14548-51-7	25g	$843.75	2026-06-04	Buy
Biosynth	PAA54851	7-Bromo-3,4-dihydro-1H-quinolin-2-one	14548-51-7	50g	$1298	2026-06-04	Buy

Product number	Packaging	Price	Buy
56602	1G	$85	Buy
56602	5G	$310	Buy
PAA54851	10g	$584.1	Buy
PAA54851	25g	$843.75	Buy
PAA54851	50g	$1298	Buy

7-Bromo-3,4-dihydro-1H-quinolin-2-one Chemical Properties,Uses,Production

Synthesis

14548-39-1

14548-51-7

6-Bromo-2,3-dihydro-1H-inden-1-one (2.0 g, 9.5 mmol) was used as starting material and dissolved in chloroform (30 mL). Under stirring, methanesulfonic acid (6 mL) was slowly added dropwise to the reaction system. Subsequently, sodium azide (1.90 g, 9.5 mmol) was added in batches, and after addition, the reaction mixture was heated to reflux for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and carefully poured into ice water. The aqueous phase was extracted with dichloromethane, the organic phases were combined and dried over anhydrous sodium sulfate. After filtration, the solvent was removed by concentration under reduced pressure to give the crude product. The crude product was purified by column chromatography (eluent: petroleum ether/ethyl acetate=2/1) to afford the target compound 7-bromo-3,4-dihydroquinolin-2(1H)-one (0.90 g) in 42% yield.

References

[1] Patent: CN106349241, 2017, A. Location in patent: Paragraph 0538; 0539; 0540; 0541; 0542
[2] Patent: WO2010/38901, 2010, A1. Location in patent: Page/Page column 44
[3] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 6, p. 662 - 667

7-Bromo-3,4-dihydro-1H-quinolin-2-one Preparation Products And Raw materials

Raw materials

6-Bromoindanone Methanesulfonic acid Sodium azide Chloroform

Preparation Products

7-BROMOQUINOLIN-2(1H)-ONE

7-Bromo-3,4-dihydro-1H-quinolin-2-one Suppliers

Global( 79)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Accela ChemBio Inc.	+1-858-6993322 +86-18019713315	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30224	58
Wuxi Rejoys chemical Technology Co., Ltd.	0510-86103381	sales@rejoyschem.com	CHINA	976	58
Suzhou Laing Biotechnology Co.,Ltd	+86-13004516015 +86-18149392822	christina@laingbiotec.com	China	777	58
SUZHOU SENFEIDA CHEMICAL CO.,LTD	+86-0512-83500002 +86-15195660023	3899766280@qq.com	China	26362	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Suzhou ARTK Medchem Co., Ltd.	+86-18168183658	sales1@artkmedchem.com	China	39021	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131956	58

Supplier	Advantage
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Career Henan Chemica Co	58
Wuxi Rejoys chemical Technology Co., Ltd.	58
Suzhou Laing Biotechnology Co.,Ltd	58
SUZHOU SENFEIDA CHEMICAL CO.,LTD	58
Aladdin Scientific	58
Suzhou ARTK Medchem Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
Amadis Chemical Company Limited	58

View Lastest Price from 7-Bromo-3,4-dihydro-1H-quinolin-2-one manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-01-27	7-Bromo-3,4-dihydro-1H-quinolin-2-one 14548-51-7		1KG	98.7%	100 tons	Honest Joy Holdings Limited

7-Bromo-3,4-dihydro-1H-quinolin-2-one
14548-51-7
$0.00
98.7%
Honest Joy Holdings Limited

7-Bromo-3,4-dihydro-1H-quinolin-2-one Spectrum

7-Bromo-3,4-dihydro-1H-quinolin-2-one(14548-51-7)¹HNMR

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7-Bromo-3,4-dihydro-1H-quinolin-2-one 7-BROMO-1,2,3,4-TETRAHYDRO-2-QUINOLINONE 7-BROMO-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 1G 2(1H)-Quinolinone, 7-bromo-3,4-dihydro- 7-Bromo-3,4-dihydro-1H-quinoline-2-one 7-Bromo-3,4-dihydro-2(1H)-quinolinone 7-broMo-3,4-dihydroquinolin-2(1H)-one 14548-51-7