ChemicalBook >> CAS DataBase List >>O-TOLUENESULFONYL CHLORIDE
O-TOLUENESULFONYL CHLORIDE
- CAS No.
- 133-59-5
- Chemical Name:
- O-TOLUENESULFONYL CHLORIDE
- Synonyms
- 2-METHYLBENZENESULFONYL CHLORIDE;o-Toluenesulfochloride;o-tosylchloride;o-Tosyl chloride;Paroxetine Impurity 30;o-tolylsulfonylchloride;containsca23%isomer)75+%;2-TOLUENESULFONYL CHLORIDE;O-TOLUENESULFONYL CHLORIDE;ortho-toluenesulfochloride
- CBNumber:
- CB0259602
- Molecular Formula:
- C7H7ClO2S
- Molecular Weight:
- 190.65
- MDL Number:
- MFCD00024874
- MOL File:
- 133-59-5.mol
- MSDS File:
- SDS
Last updated:2026-01-13 11:13:13
| Product description | Number | Pack Size | Price |
| o-Toluenesulfonyl chloride 97% | 557323 | 1g | $33.4 |
| o-Toluenesulfonyl chloride 97% | 557323 | 5g | $87.7 |
| o-Toluenesulfonyl Chloride (contains ca. 23% isomer) >75.0%(GC) | T0284 | 25g | $59 |
| o-Toluenesulfonyl Chloride (contains ca. 23% isomer) >75.0%(GC) | T0284 | 500g | $225 |
| o-Toluenesulfonyl Chloride | 461369 | 1g | $319 |
| More product size | |||
| Melting point | 10°C |
|---|---|
| Boiling point | 254 °C(lit.) |
| Density | 1.320 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Store under inert gas |
| solubility | Acetonitrile (Slightly), Chloroform(Slightly) |
| form | clear liquid |
| color | Colorless to Light yellow |
| Water Solubility | Soluble in hot alcohol, ether and benzene. Reacts with water. |
| Sensitive | Moisture Sensitive |
| BRN | 973180 |
| InChI | InChI=1S/C7H7ClO2S/c1-6-4-2-3-5-7(6)11(8,9)10/h2-5H,1H3 |
| InChIKey | HDECRAPHCDXMIJ-UHFFFAOYSA-N |
| SMILES | C1(S(Cl)(=O)=O)=CC=CC=C1C |
| CAS DataBase Reference | 133-59-5(CAS DataBase Reference) |
| FDA UNII | 341L82E3WG |
| EPA Substance Registry System | Benzenesulfonyl chloride, 2-methyl- (133-59-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P310 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Corrosive | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2904100090 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Hazardous Substances Data | 133-59-5(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
O-TOLUENESULFONYL CHLORIDE price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 557323 | o-Toluenesulfonyl chloride 97% | 133-59-5 | 1g | $33.4 | 2022-05-15 | Buy |
| Sigma-Aldrich | 557323 | o-Toluenesulfonyl chloride 97% | 133-59-5 | 5g | $87.7 | 2022-05-15 | Buy |
| TCI Chemical | T0284 | o-Toluenesulfonyl Chloride (contains ca. 23% isomer) >75.0%(GC) | 133-59-5 | 25g | $59 | 2025-07-31 | Buy |
| TCI Chemical | T0284 | o-Toluenesulfonyl Chloride (contains ca. 23% isomer) >75.0%(GC) | 133-59-5 | 500g | $225 | 2025-07-31 | Buy |
| Usbiological | 461369 | o-Toluenesulfonyl Chloride | 133-59-5 | 1g | $319 | 2021-12-16 | Buy |
O-TOLUENESULFONYL CHLORIDE Chemical Properties,Uses,Production
Chemical Properties
Oily liquid. Melting point 10.2°C, boiling point 154°C (4.8kPa), 126°C (1.33kPa), relative density 1.3383 (20/4°C), refractive index 1.5565. soluble in hot alcohols, ethers, benzene, insoluble in water.
Uses
o-Toluenesulfonyl chloride is used in organic synthesis and saccharin production. It is also used as pharmaceutical intermediate.
Uses
o-Toluenesulfonyl chloride may be used in the synthesis of:
- oxazoline
- mesityl o-tolyl sulfone
- allyl o-toluenesulfonate
- 2-methyl-4′-t-butyldiphenyl sulfone
General Description
o-Toluenesulfonyl chloride can be synthesized by reacting o-thiocresol in glacial acetic acid with chlorine. It participates in the preparation of 5-chloro-3-phenyl-2,1-benzisoxazole.
O-TOLUENESULFONYL CHLORIDE Preparation Products And Raw materials
Raw materials
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Preparation Products
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Global( 142)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from O-TOLUENESULFONYL CHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-29 | o-Toluenesulfonyl chloride
133-59-5
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-09-25 | O-TOLUENESULFONYL CHLORIDE
133-59-5
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2025-05-26 | O-TOLUENESULFONYL CHLORIDE
133-59-5
|
US $9.00 / KG | 1KG | 99% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- o-Toluenesulfonyl chloride
133-59-5
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- O-TOLUENESULFONYL CHLORIDE
133-59-5
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- O-TOLUENESULFONYL CHLORIDE
133-59-5
- US $9.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
133-59-5(O-TOLUENESULFONYL CHLORIDE)Related Search:
Tosyl chloride
2-Methylbenzene-1-sulfonamide
Mesitylene-2-sulfonyl chloride
Methyl 2-(chlorosulfonyl)benzoate
4-CHLORO-2,5-DIMETHYLBENZENESULFONYL CHLORIDE
5-NITRO-O-TOLUENESULFONYL CHLORIDE
4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE
1,2-NAPHTHOQUINONE-2-DIAZIDO-5-SULFONYL CHLORIDE
2-(Trifluoromethyl)benzenesulfonyl chloride
2,4-MESITYLENEDISULFONYL DICHLORIDE
1of4
ortho-toluenesulfonylchloride
o-Toluenesulfochloride
o-tolylsulfonylchloride
o-Tosyl chloride
o-tosylchloride
toluene-2-sulphonylchloride
ortho-toluenesulfonchloride
Paroxetine Impurity 30
o-Toluenesulphonyl chloride
containsca23%isomer)75+%
o-Toluenesulfonyl Chloride (contains ca. 23% isomer)
2-Methylbenzenesulfonic acid chloride
o-Toluenesulphonyl chloride, 2-(Chlorosulphonyl)toluene
o-Toluenesulfonyl chloride 97%
o-Toluenesulfonyl Chloride (contains ca. 23% isomer)
2-METHYLBENZENESULPHONYL CHLORIDE
2-METHYLBENZENESULFONYL CHLORIDE
2-TOLUENESULFONYL CHLORIDE
O-TOLUENESULFONYL CHLORIDE
2-methyl-benzenesulfonylchlorid
ortho-toluenesulfochloride
Benzenesulfonyl chloride, 2-methyl-
o-Toluenesulfonyl Chloride (contains ca. 23% isomer)>
O-TOLUENESULFONYL CHLORIDE ISO 9001：2015 REACH
o-Toluenesulfonyl chloride
2-Toluenesulfonyl chloride(contains ca.23% isomer)
133-59-5
C7H7ClSO2
SULFONYL CHLORIDE
Organic Building Blocks
Sulfonyl Halides
Sulfur Compounds
Building Blocks
Organic Building Blocks
Sulfonyl Halides
Sulfur Compounds
Intermediates of Dyes and Pigments
