METHYL 4-FORMYL-3-HYDROXYBENZOATE
- CAS No.
- 24589-98-8
- Chemical Name:
- METHYL 4-FORMYL-3-HYDROXYBENZOATE
- Synonyms
- ethyl 4-forMyl-3-hydroxybenzoate;4-CarboMethoxysalicylaldehyde;methyl 4-formyl-3-hydoxybenzoate;METHYL 4-FORMYL-3-HYDROXYBENZOATE;Benzoic acid, 4-formyl-3-hydroxy-, methyl ester
- CBNumber:
- CB02615936
- Molecular Formula:
- C9H8O4
- Molecular Weight:
- 180.16
- MDL Number:
- MOL File:
- 24589-98-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 4-formyl-3-hydroxybenzoate | 294912 | 1.00g | $78 |
| Methyl 4-formyl-3-hydroxybenzoate | 294912 | 5.00g | $245 |
| Methyl 4-formyl-3-hydroxybenzoate | 294912 | 25.00g | $953 |
| Methyl 4-formyl-3-hydroxybenzoate >98% | M61610 | 250mg | $30 |
| Methyl 4-formyl-3-hydroxybenzoate >98% | M61610 | 1g | $80 |
| More product size | |||
| Melting point | 135-135.5 °C(Solv: ethyl acetate (141-78-6)) |
|---|---|
| Boiling point | 324.1±27.0 °C(Predicted) |
| Density | 1.310±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 7.36±0.10(Predicted) |
| Appearance | Off-white to yellow Solid |
| InChI | InChI=1S/C9H8O4/c1-13-9(12)6-2-3-7(5-10)8(11)4-6/h2-5,11H,1H3 |
| InChIKey | OMCTZIDLDSYPOA-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC=C(C=O)C(O)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319-H315-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
METHYL 4-FORMYL-3-HYDROXYBENZOATE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 294912 | Methyl 4-formyl-3-hydroxybenzoate | 24589-98-8 | 1.00g | $78 | 2026-05-19 | Buy |
| Matrix Scientific | 294912 | Methyl 4-formyl-3-hydroxybenzoate | 24589-98-8 | 5.00g | $245 | 2026-05-19 | Buy |
| Matrix Scientific | 294912 | Methyl 4-formyl-3-hydroxybenzoate | 24589-98-8 | 25.00g | $953 | 2026-05-19 | Buy |
| Synthonix | M61610 | Methyl 4-formyl-3-hydroxybenzoate >98% | 24589-98-8 | 250mg | $30 | 2026-05-06 | Buy |
| Synthonix | M61610 | Methyl 4-formyl-3-hydroxybenzoate >98% | 24589-98-8 | 1g | $80 | 2026-05-06 | Buy |
METHYL 4-FORMYL-3-HYDROXYBENZOATE Chemical Properties,Uses,Production
Uses
4-Carbomethoxysalicylaldehyde is used in the preparation of α-glucosidase inhibitors. Also used in the preparation of β-lactamase substrates.
Synthesis
67-56-1
619-12-5
24589-98-8
Step 1: Synthesis of methyl 4-formyl-3-hydroxybenzoate (239) 4-Formyl-3-hydroxybenzoic acid (1.2 g, 7.22 mmol) was dissolved in methanol (10 ml). Sulfoxide chloride (1.054 ml, 14.45 mmol) was added slowly and the reaction mixture was stirred at 60 °C for 3 h to ensure complete reaction. After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The crude product was ground with hexane and subsequently filtered to afford methyl 4-formyl-3-hydroxybenzoate (1.3 g, 7.22 mmol, 100% yield) as a white solid. Mass spectrometric analysis (MS/ESI+) showed the molecular ion peak m/z 181.04 [MH]+.
References
[1] Patent: US2014/155391, 2014, A1. Location in patent: Paragraph 0617; 0618
[2] Patent: US2012/245144, 2012, A1. Location in patent: Page/Page column 105
[3] Journal of the American Chemical Society, 1955, vol. 77, p. 973,979
[4] Journal of Medicinal Chemistry, 1969, vol. 12, # 3, p. 420 - 424
[5] Bioorganic and Medicinal Chemistry, 2001, vol. 9, # 5, p. 1175 - 1183
METHYL 4-FORMYL-3-HYDROXYBENZOATE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xiamen Shindano Biotechnology Co.,ltd | 0592-6266840 15750707980 | sales@chemsdano.com | China | 291 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Compound Net Biotechnology Inc. | +8615303909093 | sales@compound-net.com | China | 2914 | 58 |
| HANGZHOU HAILAN CHEMICAL CO.,LTD. | +86-57156122185 +86-15967590394 | sales@hailan-chem.com | China | 2998 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
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