Viquidacin
- CAS No.
- 904302-98-3
- Chemical Name:
- Viquidacin
- Synonyms
- NXL 101;Viquidacin;USGHRRVFKSLEJT-WVBUVRCRSA-N;3-Piperidinecarboxylic acid, 4-[(3S)-3-(3-fluoro-6-methoxy-4-quinolinyl)-3-hydroxypropyl]-1-[2-(2-thienylthio)ethyl]-, (3R,4R)-
- CBNumber:
- CB02628521
- Molecular Formula:
- C25H29FN2O4S2
- Molecular Weight:
- 504.64
- MDL Number:
- MFCD13152405
- MOL File:
- 904302-98-3.mol
| Boiling point | 702.5±60.0 °C(Predicted) |
|---|---|
| Density | 1.37±0.1 g/cm3(Predicted) |
| pka | 3.81±0.40(Predicted) |
| FDA UNII | 0TA0YE45QE |
Viquidacin Chemical Properties,Uses,Production
Uses
Viquidacin (NXL 101) is an antibiotic with inhibitory activity against topoisomerase IV and DNA gyrase. Viquidacin exhibits antibacterial activity against gram positive bacterial by inhibiting the supercoiling, decatenation and relaxation in strains Staphylococcus aureus and Escherichia coli in micromolar levels. Viquidacin inhibits S. aureus wildtype and mutants with MIC of 2-128 mg/L[1].
References
[1] Black MT, et al., Mechanism of action of the antibiotic NXL101, a novel nonfluoroquinolone inhibitor of bacterial type II topoisomerases. Antimicrob Agents Chemother. 2008 Sep;52(9):3339-49. DOI:10.1128/AAC.00496-08
Viquidacin Preparation Products And Raw materials
Raw materials
Preparation Products
Viquidacin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12000 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 58 |