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POLYOXIN D

POLYOXIN D structure

CAS No.: 22976-86-9

Chemical Name:: POLYOXIN D

Synonyms: polyoxinz;polyoxorim;POLYOXIN D;POLYOXIN D, STREPTOMYCES CACAOI VAR ASOENSIS;Polyoxin D, Streptomyces cacaoi var. asoensis;Polyoxin D,?Streptomyces cacaoi var. asoensis CURRENTLY UNAVAILABLE;2,3,4-tetrahydro-2,4-dioxo-d-allofuranuronosyl)-monocarbamate(ester);1-(5-(2-amino-2-deoxy-l-xylonamido)-5-deoxy-beta-5-pyrimidinecarboxylicaci;Uridine, 5′-deoxy-5′-[[(4-methoxyphenyl)diphenylmethyl]amino]-2′-O-methyl-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite];1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranulonosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyridinecarboxylic acid

CBNumber:: CB0265177

Molecular Formula:: C17H23N5O14

Molecular Weight:: 521.39

MDL Number:: MFCD00166352

MOL File:: 22976-86-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-20 15:44:42

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POLYOXIN D Properties

Melting point	173-175 °C (decomp)
Density	1.864±0.06 g/cm3(Predicted)
storage temp.	10-30°C
solubility	aqueous buffer: soluble \|\| water: soluble
pka	2.67±0.10(Predicted)
form	solid
color	white
Water Solubility	aqueous buffer: soluble water: soluble
InChIKey	ZKAPMXOKBGSLTC-AGVSZMOESA-N
FDA UNII	A2468O1N7D
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

WGK Germany	WGK 1
Storage Class	11 - Combustible Solids

POLYOXIN D price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0129673	Polyoxin D	22976-86-9	1mg	$650	2026-06-04	Buy
ChemScene	CS-0129673	Polyoxin D	22976-86-9	5mg	$1625	2026-06-04	Buy
TRC	P688083	PolyoxinD, Streptomycescacaoivar.asoensisCURRENTLYUNAVAILABLE	22976-86-9	2.5mg	$500	2021-12-16	Buy
TRC	P688083	PolyoxinD, Streptomycescacaoivar.asoensisCURRENTLYUNAVAILABLE	22976-86-9	10mg	$1865	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0129673	1mg	$650	Buy
CS-0129673	5mg	$1625	Buy
P688083	2.5mg	$500	Buy
P688083	10mg	$1865	Buy

POLYOXIN D Chemical Properties, Uses, Production

Uses

Polyoxin D,Streptomyces cacaoi var. asoensis is a specific inhibitor of fungal chitin synthetase.

Definition

ChEBI: A member of the class of polyoxins that is isolated from the soil organism Streptomyces cacaoi var. asoensis. Polyoxorim exhibits fungicidal properties and may be used on rice, industrial grounds, golf courses and parks.

Enzyme inhibitor

This pyrimidin nucleoside analogue and antifungal antibiotic (FWfree-acid = 521.39 g/mol; CAS 22976-86-9; 33401-46-6 for the zinc salt), produced by soil organisms Streptomyces cacaoi and S. piomogenus, inhibits chitin biosynthesis, Ki = 6 μM, thereby blocking septum formation. The zinc salt of polyyoxin is used to control Rice Sheath Blight, caused by the fungus Rhizoctonia solani, as well as the turfgrass disease Brown Patch, caused by other Rhizoctonia species. Polyoxin D also inhibits Neurospora crassa, but is nontoxic to land mammals, insects, or birds, when applied to plants as the wettable powder form known as Endorse. Target(s): chitin synthase (1- 24); chitin synthase B; chitin synthase, canChs1A; WdChs4p, a chitin synthase 3 homologue.

POLYOXIN D Preparation Products And Raw materials

Raw materials

Preparation Products

POLYOXIN D Suppliers

Global Suppliers ( 28)

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang Huida Biotech Co., Ltd.	0571-89903022 18679456698	zilong@hizyme.com	China	7853	58
T&W GROUP	021-61551611 13296011611	contact@trustwe.com	China	9884	58
Shanghai Haozhixiang Biotechnology Co., Ltd	526763801 13301653310	526763801@qq.com	China	7983	55
NewCan Biotech Limited	+86-571-86912261 19975279805	sales@newcanbio.com	China	9984	58
Zhejiang Huida Biotech Co., LTD	008613515763466 8615669048680	wendy@huidabiotech.com	CHINA	87	58
BOC Sciences	16314854226	inquiry@bocsci.com	United States	9713	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19935	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413	contact@trustwe.com	China	5771	58
Zhejiang Huida Biotech Co., LTD	0571-89903022 18679456698	zilong@hizyme.com	China	8001	58
Energy Chemical	400-0056266	marketing1@energy-chemical.com	China	44927	58

Supplier	Advantage
Zhejiang Huida Biotech Co., Ltd.	58
T&W GROUP	58
Shanghai Haozhixiang Biotechnology Co., Ltd	55
NewCan Biotech Limited	58
Zhejiang Huida Biotech Co., LTD	58
BOC Sciences	58
BOC Sciences	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Zhejiang Huida Biotech Co., LTD	58
Energy Chemical	58

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POLYOXIN D POLYOXIN D, STREPTOMYCES CACAOI VAR ASOENSIS 1-(5-(2-amino-2-deoxy-l-xylonamido)-5-deoxy-beta-5-pyrimidinecarboxylicaci 2,3,4-tetrahydro-2,4-dioxo-d-allofuranuronosyl)-monocarbamate(ester) polyoxinz polyoxorim 1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranulonosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyridinecarboxylic acid 1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranuronosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid β-D-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1-(5-carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy- Polyoxin D,?Streptomyces cacaoi var. asoensis CURRENTLY UNAVAILABLE Polyoxin D, Streptomyces cacaoi var. asoensis Uridine, 5′-deoxy-5′-[[(4-methoxyphenyl)diphenylmethyl]amino]-2′-O-methyl-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] 22976-86-9 C17H23N5O14