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1-Boc-4-amino-4-piperidineacetic acid

1-Boc-4-amino-4-piperidineacetic acid Structure
1-Boc-4-amino-4-piperidineacetic acid structure
CAS No.
1159983-30-8
Chemical Name:
1-Boc-4-amino-4-piperidineacetic acid
Synonyms
2-(4-Amino-1-(tert-butoxycarbonyl);1-Boc-4-amino-4-piperidineacetic acid;4-Amino-N1-BOC-4-piperidineacetic acid;2-(1-Boc-4-amino-4-piperidyl)acetic Acid;2-(4-Amino-1-boc-piperidin-4-yl)acetic Acid;2-(4-AMINO-1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)ACETIC ACID;4-Amino-1-[(1,1-dimethylethoxy)carbonyl]-4-piperidineacetic acid;4-Piperidineacetic acid, 4-amino-1-[(1,1-dimethylethoxy)carbonyl]-;2-[4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid
CBNumber:
CB0274067
Molecular Formula:
C12H22N2O4
Molecular Weight:
258.31
MDL Number:
MFCD08460439
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-05-27 17:33:34
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1-Boc-4-amino-4-piperidineacetic acid Properties

Boiling point 398.9±27.0 °C(Predicted)
Density 1.158±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 4.66±0.10(Predicted)
InChI InChI=1S/C12H22N2O4/c1-11(2,3)18-10(17)14-6-4-12(13,5-7-14)8-9(15)16/h4-8,13H2,1-3H3,(H,15,16)
InChIKey BGBMNGXKKOJOSX-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(N)(CC(O)=O)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

1-Boc-4-amino-4-piperidineacetic acid price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 302206 2-(4-Amino-1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid 1159983-30-8 100.00mg $71 2026-05-19 Buy
Matrix Scientific 302206 2-(4-Amino-1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid 1159983-30-8 250.00mg $126 2026-05-19 Buy
Matrix Scientific 302206 2-(4-Amino-1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid 1159983-30-8 1.00g $256 2026-05-19 Buy
Synthonix A37078 2-(4-Amino-1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid 90+% 1159983-30-8 100mg $140 2026-05-06 Buy
Synthonix A37078 2-(4-Amino-1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid 90+% 1159983-30-8 250mg $220 2026-05-06 Buy
Product number Packaging Price Buy
302206 100.00mg $71 Buy
302206 250.00mg $126 Buy
302206 1.00g $256 Buy
A37078 100mg $140 Buy
A37078 250mg $220 Buy

1-Boc-4-amino-4-piperidineacetic acid Chemical Properties, Uses, Production

Uses

1-Boc-4-amino-4-piperidineacetic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Synthesis_1159983-30-8
A mixture of 4-oxo-piperidine- 1 -carboxylic acid tert-butyl ester (3.5 g, 17.55 mmol) (Sigma- Aldrich), malonic acid (2.0 g, 19.30 mmol) and ammonium acetate (3.1 g, 40.36 mmol) in n-BuOH was refluxed for 3 h. After cooled, white solid was collected, rinsed with EtOAc and dried in vacuo to provide the title compound 1.61 g (6.2 mmol) in 36% yield.

References

[1] Patent: WO2013/134660, 2013, A1. Location in patent: Paragraph 0373
[2] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 10, p. 1071 - 1074

1-Boc-4-amino-4-piperidineacetic acid synthesis

141-82-2
79099-07-3
1159983-30-8
Synthesis of 1-Boc-4-amino-4-piperidineacetic acid from Malonic acid and N-(tert-Butoxycarbonyl)-4-piperidone

1-Boc-4-amino-4-piperidineacetic acid Preparation Products And Raw materials

Raw materials

Malonic acid N-(tert-Butoxycarbonyl)-4-piperidone tert-Butanol Ammonium acetate

Preparation Products

1-Boc-4-amino-4-piperidineacetic acid Suppliers

Global Suppliers ( 43)
Supplier Tel Email Country ProdList Advantage
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16306 64
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Zhengzhou HSH Science & Technology Co., Ltd. 0371-55932928 18937192232; 1282296214@qq.com China 499 55
Tianjin Anhao Biological Technology Co., Ltd. sales@ahpharmatech.com China 5734 55
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 027-65388397 18164111589 3321478047@qq.com China 2002 55
Shanghai GL Peptide Ltd. +86-21-61263310 13764994101 fisherwang@glschina.com China 8059 55
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9729 58
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58
Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9957 58
Supplier Advantage
Tetranov Biopharm 64
Nanjing Chemlin Chemical Co., Ltd 64
Hangzhou Sage Chemical Co., Ltd. 58
Zhengzhou HSH Science & Technology Co., Ltd. 55
Tianjin Anhao Biological Technology Co., Ltd. 55
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 55
Shanghai GL Peptide Ltd. 55
Shanghai Chaolan Chemical Technology Center 58
Amatek Scientific Co. Ltd. 58
Hangzhou Molcore Biopharmatech Co.,Ltd 58

1159983-30-8 (1-Boc-4-amino-4-piperidineacetic acid) Related Search:

4-(Boc-amino)-4-piperidineacetic acid (4-Aminopiperidin-4-yl)aceticacid,N1-BOC4-FMOCprotected 2-(4-amino-1-methylpiperidin-4-yl)acetic acid 1-Cbz-4-amino-4-piperidineacetic acid 2-(1-((benzyloxy)carbonyl)-4-((tert-butoxycarbonyl)amino)piperidin-4-yl)acetic acid
2-(1-Boc-4-(Cbz-amino)-piperidin-4-yl)acetic acid

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2-(4-AMINO-1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)ACETIC ACID 1-Boc-4-amino-4-piperidineacetic acid 2-(4-Amino-1-(tert-butoxycarbonyl) 2-[4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid 2-(1-Boc-4-amino-4-piperidyl)acetic Acid 4-Piperidineacetic acid, 4-amino-1-[(1,1-dimethylethoxy)carbonyl]- 2-(4-Amino-1-boc-piperidin-4-yl)acetic Acid 4-Amino-1-[(1,1-dimethylethoxy)carbonyl]-4-piperidineacetic acid 4-Amino-N1-BOC-4-piperidineacetic acid 1159983-30-8 CHIRAL CHEMICALS