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1,4-Dichloro-2-butyne

1,4-Dichloro-2-butyne Structure
1,4-Dichloro-2-butyne structure
CAS No.
821-10-3
Chemical Name:
1,4-Dichloro-2-butyne
Synonyms
1,4-Dichlorobutyne;DK925;DKSI002;DKFELEX0248;Dichlorobutyne;1,4-Dichlorbut-2-in;1,4-dichloro-2-butyn;1,4-dichloro-1-butyne;1,4-DICHLORO-2-BUTYNE;1,4-dichlorobut-1-yne
CBNumber:
CB0276041
Molecular Formula:
C4H4Cl2
Molecular Weight:
122.98
MDL Number:
MFCD00000981
MOL File:
821-10-3.mol
MSDS File:
SDS
Last updated:2026-01-13 11:12:51
Product description Number Pack Size Price
1,4-Dichloro-2-butyne 99% D59607 5g $98.8
1,4-Dichloro-2-butyne 99% D59607 25g $272
1,4-Dichloro-2-butyne >97.0%(GC) D1528 5g $32
1,4-Dichloro-2-butyne >97.0%(GC) D1528 25g $100
1,4-Dichloro-2-butyne 99% D59607 100g $995
More product size
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1,4-Dichloro-2-butyne Properties

Melting point 162-165 °C
Boiling point 165-168 °C (lit.)
Density 1.258 g/mL at 25 °C (lit.)
refractive index n20/D 1.505(lit.)
Flash point 320 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Oil
color Clear Colourless
Sensitive Light Sensitive
BRN 635740
InChI 1S/C4H4Cl2/c5-3-1-2-4-6/h3-4H2
InChIKey RCHDLEVSZBOHOS-UHFFFAOYSA-N
SMILES ClCC#CCCl
CAS DataBase Reference 821-10-3(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference 2-Butyne, 1,4-dichloro-(821-10-3)
EPA Substance Registry System 1,4-Dichloro-2-butyne (821-10-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS07
Signal word  Warning
Hazard statements  H301-H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P264-P270-P280-P301+P310+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P405-P501
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,T
Risk Statements  36/37/38-40-23/24/25
Safety Statements  26-36-45-38-36/37/39-28A
RIDADR  UN 2810
WGK Germany  3
RTECS  ER9600000
F  8-10
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  II
HS Code  29032900
Storage Class 10 - Combustible liquids
Limited Quantities 100ml (liquid) or 0.5 Kg (solid)
Excepted Quantities Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
2 0

1,4-Dichloro-2-butyne price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D59607 1,4-Dichloro-2-butyne 99% 821-10-3 5g $98.8 2026-03-19 Buy
Sigma-Aldrich D59607 1,4-Dichloro-2-butyne 99% 821-10-3 25g $272 2026-03-19 Buy
TCI Chemical D1528 1,4-Dichloro-2-butyne >97.0%(GC) 821-10-3 5g $32 2026-03-19 Buy
TCI Chemical D1528 1,4-Dichloro-2-butyne >97.0%(GC) 821-10-3 25g $100 2026-03-19 Buy
Sigma-Aldrich D59607 1,4-Dichloro-2-butyne 99% 821-10-3 100g $995 2026-03-19 Buy
Product number Packaging Price Buy
D59607 5g $98.8 Buy
D59607 25g $272 Buy
D1528 5g $32 Buy
D1528 25g $100 Buy
D59607 100g $995 Buy

1,4-Dichloro-2-butyne Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLORLESS TO YELLOWISH LIQUID

Uses

1,4-Dichloro-2-butyne used in the synthesis of 1,4-disubstituted 1,2,3-triazoles. Also, it is used in the approach of the 20S-camptothecin family of antitumor agents.

Preparation

1,4-Dichloro-2-butyne could be conveniently prepared by treating 1,4-butynediol with Thionyl Chloride. However, as a precautionary measure, the medium is diluted with CH2Cl2 and cooled to 30°C before adding thionyl chloride to avoid hazards associated with the exothermicity of the reaction.

Reactions

1,4-Dichloro-2-butyne can be converted into other compounds such as amides, ethers, and esters using ethyl diazoacetate.

Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic fumes of Cl-. Probably a dangerous fKe and explosion hazard. See also ACETYLENE COMPOUNDS and CHLORINATED HYDROCARBONS, ALIPHATIC

1,4-Dichloro-2-butyne synthesis

110-65-6
821-10-3
Synthesis of 1,4-Dichloro-2-butyne from 2-Butyne-1,4-diol

1,4-Dichloro-2-butyne Preparation Products And Raw materials

Raw materials

2-Butyne-1,4-diol Pyridine Benzene Thionyl chloride

Preparation Products

4-CHLORO-2-BUTYN-1-OL 5-methyl-1H-pyrrole-2-carbonitrile(SALTDATA: FREE) 2-Chloro-1-buten-3-yne 1-METHOXY-1-BUTEN-3-YNE

1,4-Dichloro-2-butyne Suppliers

Global( 235)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zhuangming Biopharma Co., Ltd.
inquiry@zmsilane.com China 728 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13815 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29821 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
HaBo Hong Kong Co., Limited. 		+86-25-18512596065 info@habotech.com CHINA 933 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
zhangjiagang vinsce bio-pharm. limited. 		86-512-58389969 sales1@swellxin.com CHINA 111 58
Supplier Advantage
Shanghai Zhuangming Biopharma Co., Ltd.
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
career henan chemical co 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
HaBo Hong Kong Co., Limited. 		58
CONIER CHEM AND PHARMA LIMITED 		58
zhangjiagang vinsce bio-pharm. limited. 		58

View Lastest Price from 1,4-Dichloro-2-butyne manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,4-Dichloro-2-butyne pictures 2026-03-20 1,4-Dichloro-2-butyne
821-10-3
 US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
1,4-Dichloro-2-butyne pictures 2025-12-01 1,4-Dichloro-2-butyne
821-10-3
 US $0.00-0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
1,4-Dichloro-2-butyne pictures 2025-09-25 1,4-Dichloro-2-butyne
821-10-3
 US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd

1,4-Dichloro-2-butyne Spectrum

1,4-Dichloro-2-butyne(821-10-3)MS1,4-Dichloro-2-butyne(821-10-3)1HNMR1,4-Dichloro-2-butyne(821-10-3)13CNMR1,4-Dichloro-2-butyne(821-10-3)IR11,4-Dichloro-2-butyne(821-10-3)Raman

821-10-3(1,4-Dichloro-2-butyne)Related Search:

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Propyne 1,4-Dichloro-2-butyne

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1,4-DICHLORO-2-BUTYNE 1,4-dichloro-2-butyn 1,4-dichloro-but-2-yne 1,4-Dichlorobutyne Dichlorobutyne 2-Butyne, 1,4-dichloro- bis(chloromethyl)acetylene 1,4-Dichloro-2-butyne, 99% 25ML 1,4-Dichloro-2-butyne,99% 1,4-Dichlorobut-2-yne 98+% 1,4-dichloro-1-butyne 1,4-dichlorobut-1-yne 1,4-Dichloro-2-butyne> 1,4-Dichloro-2-butyne ISO 9001：2015 REACH DK925 1,4-Dichlorbut-2-in DKFELEX0248 DKSI002 821-10-3 820-10-3 ClCH2C8801CCH2Cl C4H4Cl2 ClCH2CCCH2Cl Functionalized Acetylenes Acetylenes Building Blocks Alkynyl Halogenated Hydrocarbons Organic Building Blocks Building Blocks Chemical Synthesis Halogenated Hydrocarbons Organic Building Blocks Acetylenes Functionalized Acetylenes Alkynyl Halogenated Hydrocarbons Organic Building Blocks