Azido-PEG4-4-nitrophenyl carbonate
- CAS No.
- 1422540-98-4
- Chemical Name:
- Azido-PEG4-4-nitrophenyl carbonate
- Synonyms
- N3-PEG4-NPC;N3-PEG4-4-NPC;Reaxys ID: 23366082;Azido-PEG4-4-nitrophenyl carbonate;2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethyl (4-nitrophenyl) carbonate
- CBNumber:
- CB03062355
- Molecular Formula:
- C15H20N4O8
- Molecular Weight:
- 384.35
- MDL Number:
- MFCD28976674
- MOL File:
- 1422540-98-4.mol
- MSDS File:
- SDS
Azido-PEG4-4-nitrophenyl carbonate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | XGC54098 | Azido-PEG4-4-nitrophenyl carbonate | 1422540-98-4 | 500mg | $990 | 2026-06-05 | Buy |
| ChemScene | CS-0115226 | Azido-PEG4-4-nitrophenyl carbonate ≥97% | 1422540-98-4 | 100mg | $49 | 2026-06-04 | Buy |
| ChemScene | CS-0115226 | Azido-PEG4-4-nitrophenyl carbonate ≥97% | 1422540-98-4 | 250mg | $115 | 2026-06-04 | Buy |
| ChemScene | CS-0115226 | Azido-PEG4-4-nitrophenyl carbonate ≥97% | 1422540-98-4 | 1g | $299 | 2026-06-04 | Buy |
| BroadPharm | bp-22841 | Azido-PEG3-4-nitrophenyl carbonate 98% | 1422540-98-4 | 250MG | $360 | 2026-05-24 | Buy |
Azido-PEG4-4-nitrophenyl carbonate Chemical Properties, Uses, Production
Description
Azido-PEG4-4-nitrophenyl carbonate is a PEG linker containing an azide group and an reactive nitrophenyl carbonate(NPC group). The NPC group is reactive towards the amino group of lysine by means of stable urethane linkages. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Azido-PEG4-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-4-nitrophenyl carbonate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG4-4-nitrophenyl carbonate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
View Latest Price from Azido-PEG4-4-nitrophenyl carbonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | Azido-PEG4-4-nitrophenyl carbonate
1422540-98-4
|
$33.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | Azido-PEG4-4-nitrophenyl carbonate
1422540-98-4
|
1g | >99.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Azido-PEG4-4-nitrophenyl carbonate
1422540-98-4
- $33.00
- TargetMol Chemicals Inc.
-
- Azido-PEG4-4-nitrophenyl carbonate
1422540-98-4
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
