Cbz-N-amido-PEG5-acid
- CAS No.
- 1347750-74-6
- Chemical Name:
- Cbz-N-amido-PEG5-acid
- Synonyms
- CbzNH-P5-COOH;CBZ-NH-PEG5-COOH;Cbz-NH-PEG5-C2-acid;CbzNH-PEG5-CH2CH2COOH;CBZ-N-AMIDO-PEG5-COOH;Cbz-N-amido-PEG5-acid;CBZ-NH-PEG5-propionic acid;CBZ-18-amino-4,7,10,13,16-pentaoxaoctadecanoic acid;3-oxo-1-phenyl-2,7,10,13,16,19-hexaoxa-4-azadocosan-22-oic acid;5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid, 1-(phenylmethyl) ester
- CBNumber:
- CB03062461
- Molecular Formula:
- C21H33NO9
- Molecular Weight:
- 443.49
- MDL Number:
- MFCD28142482
- MOL File:
- 1347750-74-6.mol
| Product description | Number | Pack Size | Price |
| Cbz-N-Amido-PEG5-Acid | C227218 | 10mg | $45 |
| CbzNH-PEG5-CH2CH2COOH 95+% | AS104152 | 1g | $413 |
| Cbz-N-amido-PEG5-acid 98% | BP-22314 | 2g | $645 |
| CbzNH-PEG5-CH2CH2COOH 95+% | AS104152 | 5G | $1197 |
| CbzNH-PEG5-CH2CH2COOH 97% | B-1099 | 5g | $907.5 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
Cbz-N-amido-PEG5-acid price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C227218 | Cbz-N-Amido-PEG5-Acid | 1347750-74-6 | 10mg | $45 | 2021-12-16 | Buy |
| Activate Scientific | AS104152 | CbzNH-PEG5-CH2CH2COOH 95+% | 1347750-74-6 | 1g | $413 | 2021-12-16 | Buy |
| BroadPharm | BP-22314 | Cbz-N-amido-PEG5-acid 98% | 1347750-74-6 | 2g | $645 | 2021-12-16 | Buy |
| Activate Scientific | AS104152 | CbzNH-PEG5-CH2CH2COOH 95+% | 1347750-74-6 | 5G | $1197 | 2021-12-16 | Buy |
| Acrotein | B-1099 | CbzNH-PEG5-CH2CH2COOH 97% | 1347750-74-6 | 5g | $907.5 | 2021-12-16 | Buy |
Cbz-N-amido-PEG5-acid Chemical Properties,Uses,Production
Description
Cbz-N-amido-PEG5-acid is a PEG linker containing a CBZ-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions.
Uses
Cbz-NH-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Cbz-N-amido-PEG5-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5743 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Alabiochem Tech.Co., Ltd. | 512-58900862 400-0707518 | sales@alabiochem.com | China | 970 | 59 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9895 | 58 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 | sales@huatengsci.com | China | 5872 | 58 |
