ChemicalBook >> CAS DataBase List >>Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride
Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride
![Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride Structure](CAS/20180527/GIF/161416-61-1.gif)
- CAS No.
- 161416-61-1
- Chemical Name:
- Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride
- Synonyms
- ABT 089 dihydrochloride;Pozanicline dihydrochloride;ABT 089 dihydrochloride (ABT089;2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride;(S)-2-Methyl-3-(pyrrolidin-2-ylmethoxy)pyridine dihydrochloride;Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride;receptor,nAChR,nicotinic,acetylcholine,ABT 089,inhibit,Pozanicline,Nicotinic acetylcholine receptors,Parkinson,disease,ABT-089,Pozanicline dihydrochloride,dopamine,Alzheimer,ABT089,Inhibitor
- CBNumber:
- CB03197833
- Molecular Formula:
- C11H17ClN2O
- Molecular Weight:
- 228.72
- MDL Number:
- MFCD00929191
- MOL File:
- 161416-61-1.mol
Last updated:2025-10-14 17:28:59
| Product description | Number | Pack Size | Price |
| ABT-089 dihydrochloride ≥98%(HPLC) | 5079 | 10 | $171 |
| ABT-089 dihydrochloride ≥98%(HPLC) | 5079 | 50 | $716 |
| 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridineDihydrochloride | M327430 | 10mg | $170 |
| Pozanicline(dihydrochloride) >99.0% | CS-0033022 | 5mg | $345 |
| Pozanicline(dihydrochloride) >99.0% | CS-0033022 | 10mg | $580 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 5079 | ABT-089 dihydrochloride ≥98%(HPLC) | 161416-61-1 | 10 | $171 | 2021-12-16 | Buy |
| Tocris | 5079 | ABT-089 dihydrochloride ≥98%(HPLC) | 161416-61-1 | 50 | $716 | 2021-12-16 | Buy |
| TRC | M327430 | 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridineDihydrochloride | 161416-61-1 | 10mg | $170 | 2021-12-16 | Buy |
| ChemScene | CS-0033022 | Pozanicline(dihydrochloride) >99.0% | 161416-61-1 | 5mg | $345 | 2021-12-16 | Buy |
| ChemScene | CS-0033022 | Pozanicline(dihydrochloride) >99.0% | 161416-61-1 | 10mg | $580 | 2021-12-16 | Buy |
Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride Chemical Properties,Uses,Production
Uses
2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridine Dihydrochloride is a selective neuronal nicotinic receptor (NNR) modulator and a neuroprotective agent that has therapeutic potential for treating cognitive disorders. 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridine Dihydrochloride is selective for the neuronal nicotinic acetylcholine receptors (nAChRs) subtype, which modulate the release of neurotransmitters (acetylcholine and dopamine).
in vivo
Pozanicline (ABT-089; 0.3 mg/kg and 0.6 mg/kg) reverses nicotine withdrawal-induced deficits in contextual fear conditioning[3].
| Animal Model: | Adult male C57BL6/J mice at 8-12 weeks of age[3]. |
| Dosage: | 0.3 mg/kg and 0.6 mg/kg |
| Administration: | Treated 5 min before training and testing for contextual fear conditioning |
| Result: | A dose of 0.3 mg/kg and 0.6 mg/kg ameliorated nicotine withdrawal-induced cognitive deficits in contextual fear conditioning. |
storage
Desiccate at RT
Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride Suppliers
Global( 31)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32436 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 8508 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 4979 | 55 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
View Lastest Price from Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-18 | Pozanicline dihydrochloride
161416-61-1
|
US $79.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Pozanicline dihydrochloride
161416-61-1
- US $79.00 / mg
- TargetMol Chemicals Inc.
Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-, dihydrochloride
2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride
ABT 089 dihydrochloride
(ABT089
ABT 089 dihydrochloride
Pozanicline dihydrochloride
receptor,nAChR,nicotinic,acetylcholine,ABT 089,inhibit,Pozanicline,Nicotinic acetylcholine receptors,Parkinson,disease,ABT-089,Pozanicline dihydrochloride,dopamine,Alzheimer,ABT089,Inhibitor
(S)-2-Methyl-3-(pyrrolidin-2-ylmethoxy)pyridine dihydrochloride
161416-61-1
