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monophosphoryl lipid A

CAS No.
960324-04-3
Chemical Name:
monophosphoryl lipid A
Synonyms
phosphorylated hexaacyl disaccharide;α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-3-O-[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]-2-[[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]amino]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 3-[(3R)-3-hydroxytetradecanoate]
CBNumber:
CB03335400
Molecular Formula:
C96H181N2O22P
Molecular Weight:
1746.47
MDL Number:
MOL File:
960324-04-3.mol
Last updated:2025-04-18 09:51:34

monophosphoryl lipid A Properties

Density 1.09±0.1 g/cm3(Predicted)
pka 1.83±0.10(Predicted)
FDA UNII 6CY69F2AH3

monophosphoryl lipid A Chemical Properties,Uses,Production

Uses

Monophosphoryl lipid A (free acid) is a toll-like receptor 4 agonist. Monophosphoryl lipid A (free acid) is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A (free acid) can be used for the research of immunization and vaccine[1].

References

[1] Cheng R, et al. Recombination Monophosphoryl Lipid A-Derived Vacosome for the Development of Preventive Cancer Vaccines. ACS Appl Mater Interfaces. 2020;12(40):44554-44562. DOI:10.1021/acsami.0c15057

monophosphoryl lipid A Preparation Products And Raw materials

Raw materials

Preparation Products

monophosphoryl lipid A Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai AECOM Biotechnology Co. , Ltd. 021-021-20956531 18116226605 sui@neosunpharm.com China 349 55
phosphorylated hexaacyl disaccharide α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-3-O-[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]-2-[[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]amino]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 3-[(3R)-3-hydroxytetradecanoate] 960324-04-3 C96H181N2O22P