Methyltetrazine-NHS Ester
- CAS No.
- 1644644-96-1
- Chemical Name:
- Methyltetrazine-NHS Ester
- Synonyms
- Methyltetrazine-Ph-NHS ester;2,5-dioxopyrrolidin-1-yl 2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl)acetate;Methyltetrazine-NHS Ester;Methyltetrazine-PAA-NHS Ester;Methyltetrazine-NHS ester >=95%;Methyltetrazine-NHS Ester (CCT-1128);2,5-Dioxo-1-pyrrolidinyl 2-[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl]acetate;2,5-dioxypyrolidine-1-yl2-(4-(6-methyl-1,2,4,5-tetrazine-3-yl)phenyl)acetic acidester;Benzeneacetic acid, 4-(6-methyl-1,2,4,5-tetrazin-3-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB03345049
- Molecular Formula:
- C15H13N5O4
- Molecular Weight:
- 327.29
- MDL Number:
- MFCD28334557
- MOL File:
- 1644644-96-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 563.1±60.0 °C(Predicted) |
|---|---|
| Density | 1.48±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| pka | 1.37±0.10(Predicted) |
| form | Solid |
| color | Purple to purplish red |
| InChI | 1S/C15H13N5O4/c1-9-16-18-15(19-17-9)11-4-2-10(3-5-11)8-14(23)24-20-12(21)6-7-13(20)22/h2-5H,6-8H2,1H3 |
| InChIKey | BIHJLZOOHNOUCG-UHFFFAOYSA-N |
| SMILES | O=C(ON1C(CCC1=O)=O)CC(C=C2)=CC=C2C3=NN=C(C)N=N3 |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
Methyltetrazine-NHS Ester price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 900914 | Methyltetrazine-NHS ester ≥95% | 1644644-96-1 | 100MG | $289 | 2026-04-30 | Buy |
| TCI Chemical | M3494 | Methyltetrazine-NHS Ester | 1644644-96-1 | 25MG | $110 | 2026-04-30 | Buy |
| Biosynth | UQC64496 | Methyltetrazine-NHS ester | 1644644-96-1 | 0.5g | $649 | 2026-06-05 | Buy |
| Biosynth | UQC64496 | Methyltetrazine-NHS ester | 1644644-96-1 | 1g | $1038.4 | 2026-06-05 | Buy |
| Biosynth | UQC64496 | Methyltetrazine-NHS ester | 1644644-96-1 | 2g | $1687.4 | 2026-06-05 | Buy |
Methyltetrazine-NHS Ester Chemical Properties,Uses,Production
Description
Methyltetrazine-NHS Ester is a NHS actived building block containing a methyltetrazine group. It can react with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).
Uses
Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.
reaction suitability
reaction type: click chemistry
reagent type: cross-linking reagent
IC 50
Alkyl/ether
Methyltetrazine-NHS Ester Preparation Products And Raw materials
Raw materials
Preparation Products
Methyltetrazine-NHS Ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 | 3927209986@qq.com | China | 9997 | 55 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Henan's chemical products co., LTD | 0371-60919097 15378766539; | 794449696@qq.com | China | 4990 | 58 |
View Lastest Price from Methyltetrazine-NHS Ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-15 | Methyltetrazine-Ph-NHS ester
1644644-96-1
|
10g | TargetMol Chemicals Inc. | ||||
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2025-06-07 | Methyltetrazine-NHS ester
1644644-96-1
|
100mg | >99.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-

- Methyltetrazine-Ph-NHS ester
1644644-96-1
- $0.00
- TargetMol Chemicals Inc.
-

- Methyltetrazine-NHS ester
1644644-96-1
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.




