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GSK-LSD1 Dihydrochloride

GSK-LSD1 Dihydrochloride Structure
GSK-LSD1 Dihydrochloride structure
CAS No.
2102933-95-7
Chemical Name:
GSK-LSD1 Dihydrochloride
Synonyms
GSK-LSD1 2HCl ，S7574;GSK-LSD1 dihydrochloride, 10 mM in DMSO;GSK LSD1 dihydrochloride,Monoamine Oxidase,GSK-LSD-1 dihydrochloride,Inhibitor,inhibit,GSK-LSD1,MAO,GSKLSD1 dihydrochloride,Histone Demethylase
CBNumber:
CB03356155
Molecular Formula:
C14H21ClN2
Molecular Weight:
252.79
MDL Number:
MOL File:
2102933-95-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:50
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GSK-LSD1 Dihydrochloride Properties

storage temp. Store at -20°C
solubility DMF: 1 mg/ml; DMSO: 25 mg/ml; Ethanol: 0.1 mg/ml; PBS (pH 7.2): 10 mg/ml
form A crystalline solid
color White to light yellow

GSK-LSD1 Dihydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16439 GSK-LSD1 (hydrochloride) ≥98% 2102933-95-7 1mg $36 2026-04-30 Buy
Cayman Chemical 16439 GSK-LSD1 (hydrochloride) ≥98% 2102933-95-7 5mg $95 2026-04-30 Buy
Cayman Chemical 16439 GSK-LSD1 (hydrochloride) ≥98% 2102933-95-7 10mg $169 2026-04-30 Buy
Cayman Chemical 16439 GSK-LSD1 (hydrochloride) ≥98% 2102933-95-7 25mg $378 2026-04-30 Buy
Biosynth CJD93395 GSK-LSD1 dihydrochloride 2102933-95-7 5mg $250 2026-06-04 Buy
Product number Packaging Price Buy
16439 1mg $36 Buy
16439 5mg $95 Buy
16439 10mg $169 Buy
16439 25mg $378 Buy
CJD93395 5mg $250 Buy

GSK-LSD1 Dihydrochloride Chemical Properties, Uses, Production

Description

Lysine-specific demethylase 1 (LSD1) belongs to the family of flavin adenine dinucleotide (FAD)-dependent amine oxidases that include monoamine oxidases (MAOs) and polyamine oxidase (PAO).1 LSD1 specifically demethylates mono- and dimethylated histone H3 lysine 4, resulting in transcriptional repression.2 It also controls the tumor suppressor activity of p53 by demethylating a specific p53 lysine residue (LYS370).3 GSK-LSD1 is an irreversible, mechanism-based inhibitor of LSD1 (IC50 = 16 nM) that is >1,000-fold selective over the closely related FAD-utilizing enzymes LSD2, MAO-A, and MAO-B.4 GSK-LSD1 induces gene expression changes in various cancer cell lines, inhibiting their proliferation (EC50s <5 nM).4 See the Structural Genomics Consortium (SGC) website for more information.

Uses

GSK-LSD1 dihydrochloride is a potent, selective and irreversible lysine specific demethylase 1 (LSD1) inhibitor with an IC50 of 16 nM.

storage

Store at +4°C

References

1. Shi, Y., Lan, F., Matson, C., et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1 Cell 119(7),941-953(2004).
2. Forneris, F., Binda, C., Vanoni, M.A., et al. Human histone demethylase LSD1 reads the histone code J. Biol. Chem. 280(50),41360-41365(2005).
3. Huang, J., Sengupta, R., Espejo, A.B., et al. p53 is regulated by the lysine demethylase LSD1 Nature 449,105-108(2007).
4. Epigenetics probes collection ,(2014).

GSK-LSD1 Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

GSK-LSD1 Dihydrochloride Suppliers

Global Suppliers ( 35)
Supplier Tel Email Country ProdList Advantage
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Qingdao IniKem BioPharmaTech Co.,Ltd 0532-58268781 18561687109 sales@inikem.com China 299 55
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3307 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946 1461866103@qq.com China 16103 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5123 58
Supplier Advantage
MedChemexpress LLC 58
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Qingdao IniKem BioPharmaTech Co.,Ltd 55
Angel Pharmatech, Ltd. 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Beijing xinyanhui pharmaceutical research and development co., LTD 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai hongqu biomedical technology co. LTD 58

2102933-95-7 (GSK-LSD1 Dihydrochloride) Related Search:

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GSK LSD1 dihydrochloride,Monoamine Oxidase,GSK-LSD-1 dihydrochloride,Inhibitor,inhibit,GSK-LSD1,MAO,GSKLSD1 dihydrochloride,Histone Demethylase GSK-LSD1 dihydrochloride, 10 mM in DMSO GSK-LSD1 2HCl ，S7574 2102933-95-7