Sulfo DBCO-PEG4-amine
- CAS No.
- 2055198-05-3
- Chemical Name:
- Sulfo DBCO-PEG4-amine
- Synonyms
- Sulfo DBCO-PEG4-NH2;12,15,18,21-Tetraoxa-4,8-diazatricosane-6-sulfonic acid, 23-amino-1-(11,12-dihydrodibenz[b,f]azocin-5(6H)-yl)-1,5,9-trioxo-
- CBNumber:
- CB03363995
- Molecular Formula:
- C32H42N4O10S
- Molecular Weight:
- 674.77
- MDL Number:
- MFCD30458045
- MOL File:
- 2055198-05-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Sulfo DBCO-PEG4-amine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114854 | Sulfo DBCO-PEG4-amine ≥97% | 2055198-05-3 | 5mg | $236 | 2026-06-04 | Buy |
| ChemScene | CS-0114854 | Sulfo DBCO-PEG4-amine ≥97% | 2055198-05-3 | 10mg | $379 | 2026-06-04 | Buy |
| BroadPharm | bp-23310 | Sulfo DBCO-PEG4-amine 95% | 2055198-05-3 | 25MG | $265 | 2026-05-24 | Buy |
| BroadPharm | bp-23310 | Sulfo DBCO-PEG4-amine 95% | 2055198-05-3 | 50MG | $420 | 2026-05-24 | Buy |
| BroadPharm | bp-23310 | Sulfo DBCO-PEG4-amine 95% | 2055198-05-3 | 100MG | $655 | 2026-05-24 | Buy |
Sulfo DBCO-PEG4-amine Chemical Properties, Uses, Production
Description
Sulfo DBCO-PEG4-Amine is a water-soluble carboxyl-reactive building block with extended PEG spacer arm. In the presence of of activators (e.g. EDC, or HATU), this reagent can be used to derivatize carboxyl groups or activated esters (e.g. The NHS ester) through a stable amide bond. The hydrophilic sulfonated spacer arm greatly improves water solubility of DBCO derivatized molecules and a provides a long and flexible connection. DBCO is commonly used for copper-free Click Chemistry reactions.
Uses
Sulfo DBCO-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Sulfo DBCO-PEG4-amine Preparation Products And Raw materials
Raw materials
Preparation Products
Sulfo DBCO-PEG4-amine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1978 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Hubei wei shi reagent group ltd., company | 027-59102966 18717199209 | 2853877583@qq.com | China | 2896 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| Guangzhou Weihua Biotechnology Co., Ltd | 020-37239396 18922496242 | weihuasw@foxmail.com | China | 5000 | 58 |
