DSPE-PEG5-propargyl
- CAS No.
- 2112737-93-4
- Chemical Name:
- DSPE-PEG5-propargyl
- Synonyms
- DSPE-PEG5-proparg;DSPE-PEG5-propargl;DSPE-PEG5-propargyl;Octadecanoic acid, (2R)-5-hydroxy-5-oxido-10-oxo-2-[(1-oxooctadecyl)oxy]-4,6,13,16,19,22,25-heptaoxa-9-aza-5-phosphaoctacos-27-yn-1-yl ester
- CBNumber:
- CB03373615
- Molecular Formula:
- C55H104NO14P
- Molecular Weight:
- 1034.39
- MDL Number:
- MFCD30828697
- MOL File:
- 2112737-93-4.mol
DSPE-PEG5-propargyl price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA019EBB | DSPE-PEG5-propargyl ≥95% | 2112737-93-4 | 25mg | $395 | 2026-05-29 | Buy |
| aablocks | AA019EBB | DSPE-PEG5-propargyl ≥95% | 2112737-93-4 | 50mg | $645 | 2026-05-29 | Buy |
| aablocks | AA019EBB | DSPE-PEG5-propargyl ≥95% | 2112737-93-4 | 100mg | $1120 | 2026-05-29 | Buy |
| BroadPharm | BP-23659 | DSPE-PEG5-propargyl 98% | 2112737-93-4 | 50mg | $480 | 2021-12-16 | Buy |
DSPE-PEG5-propargyl Chemical Properties, Uses, Production
Description
DSPE-PEG8-propargyl is a PEG linker with attached DSPE and propargyl groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The hydrophilic PEG linker increases the water solubility of the compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
Uses
DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DSPE-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
DSPE-PEG5-propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
DSPE-PEG5-propargyl Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 9957 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1977 | 58 |
| Hangzhou Taorui Biotechnology Co., Ltd | QQ1259737804 15268198094 | sales@torreybio.com | China | 4129 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38900 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | hanfangpharma@126.com 18017580634 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
View Latest Price from DSPE-PEG5-propargyl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | DSPE-PEG5-propargyl
2112737-93-4
|
100mg | >98.00% | 100mg | Xian confluore Biological Technology Co., Ltd. | ||
 |
2025-04-04 | DSPE-PEG5-propargyl
2112737-93-4
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- DSPE-PEG5-propargyl
2112737-93-4
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
-
- DSPE-PEG5-propargyl
2112737-93-4
- 98%
- Henan Aochuang Chemical Co.,Ltd.
