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DICHLORISONE ACETATE

DICHLORISONE ACETATE Structure
DICHLORISONE ACETATE structure
CAS No.
79-61-8
Chemical Name:
DICHLORISONE ACETATE
Synonyms
Sch 5005;DICHLORISONE ACETATE;dichlorisone 21-acetate;Dichlorisone Acetate, 10 mM in DMSO;21-Acetyloxy-9,11β-dichloro-17-hydroxypregna-1,4-diene-3,20-dione;1, 4-PREGNADIEN-9α, 11β-DICHLORO-17, 21-DIOL-3, 20-DIONE 21-ACETATE;9α,11β-Dichloro-17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate;1,4-PREGNADIEN-9-ALPHA, 11-BETA-DICHLORO-17,21-DIOL-3,20-DIONE 21-ACETATE;inhibit,Inhibitor,Dichlorisone,Endogenous Metabolite,Dichlorisone Acetate;Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11b)-
CBNumber:
CB0339584
Molecular Formula:
C23H28Cl2O5
Molecular Weight:
455.37
MDL Number:
MFCD00133265
MOL File:
79-61-8.mol
MSDS File:
SDS
Last updated:2025-10-09 14:55:14
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DICHLORISONE ACETATE Properties

Melting point 246-253 °C (decomp)
alpha D25 +162° (dioxane)
Boiling point 596.2±50.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 4.35 mg/mL (9.55 mM); Water: < 0.1 mg/mL (insoluble)
pka 11.94±0.70(Predicted)
form Solid
color White to off-white
FDA UNII 64FTA4579H

SAFETY

Risk and Safety Statements

WGK Germany  3

DICHLORISONE ACETATE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-7866 Dichlorisone acetate 99.77% 79-61-8 10mg $60 2021-12-16 Buy
ChemScene CS-7866 Dichlorisone acetate 99.77% 79-61-8 50mg $108 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000402 DICHLORISONE ACETATE 95.00% 79-61-8 500MG $597.4 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000402 DICHLORISONE ACETATE 95.00% 79-61-8 1G $695.39 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000402 DICHLORISONE ACETATE 95.00% 79-61-8 5G $1050.24 2021-12-16 Buy
Product number Packaging Price Buy
CS-7866 10mg $60 Buy
CS-7866 50mg $108 Buy
SHG0000402 500MG $597.4 Buy
SHG0000402 1G $695.39 Buy
SHG0000402 5G $1050.24 Buy

DICHLORISONE ACETATE Chemical Properties,Uses,Production

Originator

Diloderm ,Schering,US,1960

Uses

antipruretic

Definition

ChEBI: Dichlorisone is a corticosteroid hormone.

Manufacturing Process

A solution of 1.0 g of 1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione-21- acetate and 5.0 g of lithium chloride in 40 ml of glacial acetic acid is treated
with 0.410 g of N-chlorosuccinimide, followed by 0.104 g of anhydrous hydrogen chloride dissolved in 2.5 ml of tetrahydrofuran. The reaction mixture is stirred for 2 hours and poured into ice water. The crude product is filtered and washed with water to give 1.12 g of solid material, which is recrystallized from acetone-hexane to give substantially pure 9α,11β-dichloro-1,4- pregnadiene-17α,21-diol-3,20-dione-21-acetate; MP 246°C to 253°C (dec.).

brand name

Diloderm (Schering).

Therapeutic Function

Antipruritic, Antihistaminic, Appetite stimulant

DICHLORISONE ACETATE synthesis

84871-33-0
79-61-8
Synthesis of DICHLORISONE ACETATE from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

DICHLORISONE ACETATE Preparation Products And Raw materials

Raw materials

N-Chlorosuccinimide Triamcinolone acetonide 21-acetate Deltacortinene Acetate (Predisolone Acetate IMpurity)

Preparation Products

DICHLORISONE ACETATE Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32433 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39031 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19961 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
Target molecule Corp. 857-239-0968 service1@targetmol.com United States 2559 60
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
TargetMol Chemicals Inc. 		58
MedChemexpress LLC 58
Target molecule Corp. 60
Lynnchem 58
Novachemistry 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

View Lastest Price from DICHLORISONE ACETATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dichlorisone Acetate pictures 2025-10-09 Dichlorisone Acetate
79-61-8
 US $40.00-108.00 / mg 98.69% 10g TargetMol Chemicals Inc.
Dichlorisone Acetate pictures 2025-10-09 Dichlorisone Acetate
79-61-8
 US $40.00-108.00 / mg 98.69% 10g TargetMol Chemicals Inc.
Dichlorisone Acetate pictures 2025-05-13 Dichlorisone Acetate
79-61-8
 US $166.00-66.00 / mg 99.72% 10g TargetMol Chemicals Inc.

DICHLORISONE ACETATE Spectrum

DICHLORISONE ACETATE(79-61-8)1HNMR

79-61-8(DICHLORISONE ACETATE)Related Search:

2-CHLORO-2,3-DIMETHYL BUTANE 6-Chlorohexanol 6-Chloro-2-hexanone 1-Chlorotetradecane 6-Chlorohex-1-ene
1-CHLORO-1-METHYLCYCLOHEXANE 1,6-Dichlorohexane (R)-5-CHLORO-2-PENTANOL 1,10-Dichlorodecane 1,9-DICHLORONONANE
2,3-Dichlorobutane 9-chloronon-1-ene 1-CHLORO-3,3-DIMETHYLPENTANE 8-Chloro-1-octene 3-CHLORO-2,2,3-TRIMETHYLBUTANE
10-CHLORO-1-DECANOL CIS-6-CHLORO-2-HEXENE 7-CHLORO-1-HEPTENE

1of4

9ALPHA,11BETA-DICHLORO-17ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 21-ACETATE 1,4-PREGNADIEN-9-ALPHA, 11-BETA-DICHLORO-17,21-DIOL-3,20-DIONE 21-ACETATE dichlorisone 21-acetate 9α,11β-Dichloro-17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate 21-Acetyloxy-9,11β-dichloro-17-hydroxypregna-1,4-diene-3,20-dione Sch 5005 [2-[(9R,17R)-9,11-dichloro-17-hydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate [2-[(9R,17R)-9,11-dichloro-17-hydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate acetic acid [2-[(9R,17R)-9,11-dichloro-17-hydroxy-3-keto-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester DICHLORISONE ACETATE Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11β)- Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11b)- inhibit,Inhibitor,Dichlorisone,Endogenous Metabolite,Dichlorisone Acetate 1, 4-PREGNADIEN-9α, 11β-DICHLORO-17, 21-DIOL-3, 20-DIONE 21-ACETATE Dichlorisone Acetate, 10 mM in DMSO 79-61-8 C23H28Cl2O5 Inhibitors DILODERM